Symbol
Name
ID
|
|
|
Synonyms
|
Gads, GRAP-2, Grb2-related adaptor downstream of Sch, GRB2L, GrbX, Grf40, GRID, GrpL, Mona, P38
|
|
Genetic Map
|
|
Chromosome 15
|
cytoband E2
|
|
|
|
Mapping data(
2)
|
|
|
|
Sequence Map
|
|
Mammalian
homology
|
|
|
Sequences
|
All sequences(26)
|
Alleles
and
phenotypes
|
All alleles(2) :
Targeted, knock-out(2)
| Mice homozygous for disruptions in this gene are grossly healthy but display abnormal T cell development. |
|
|
Polymorphisms
|
SNPs within 2kb(141 from dbSNP Build 128)
|
Gene Ontology
(GO)
classifications
|
|
|
Expression
|
Literature Summary: (1 records)
Data Summary:
Assays (4)
Results (26)
Tissues (17)
Theiler Stages: 28
| |
Assay Type |
Assays |
|
Results |
| |
Western blot |
2 |
|
17 |
| |
RT-PCR |
1 |
|
6 |
| |
Northern blot |
1 |
|
3 |
cDNA source data(28)
External Resources:
Allen Brain Atlas
GEO
ArrayExpress
|
Molecular
reagents
|
All nucleic(30)
cDNA(29)
Primer pair(1)
Antibodies(1)
Microarray probesets(3)
|
Other database
links
|
| Ensembl Gene Model |
ENSMUSG00000042351 |
| DoTS |
DT.527370, DT.530391, DT.530393, DT.55247001, DT.94236868 |
| Consensus CDS Project |
CCDS27663.1 |
| UniGene |
12947 |
| PDB |
1H3H, 1OEB, 1R1P, 1R1Q, 1R1S, 1UTI, 2D0N, 2W10 |
| DFCI |
TC1587299, TC1594489, TC1597412, TC1642610 |
| NIA Mouse Gene Index |
U016450 |
| Entrez Gene |
17444 |
| International Mouse Knockout Project Status |
Grap2 |
|
Protein
domains
|
Graphical View
of Protein Domain Structure
|
|
References
|
(Earliest)
J:51801
Bourette RP et al.,
"Mona, a novel hematopoietic-specific adaptor interacting with the macrophage colony-stimulating factor receptor, is implicated in monocyte/macrophage development."
EMBO J 1998 Dec 15;17(24):7273-81
(Latest)
J:151601
Reeve JL et al.,
"SLP-76 couples Syk to the osteoclast cytoskeleton."
J Immunol 2009 Aug 1;183(3):1804-12
|
All references(18)
|
Analysis Tools
MGI BioMart