About   Help   FAQ
Tour our new Quick Search
Cenpf Gene Detail
 Symbol
Name
ID
Cenpf
centromere protein F
MGI:1313302

Nomenclature History
Synonyms 6530404A22Rik, Lek1, mitosin
Genetic Map
Chromosome 1
106.3 cM
Detailed Genetic Map ± 1 cM
 
Mapping data( 3)

Sequence Map
Chr1:191464495-191511965 bp, - strand
(From Ensembl annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Cenpf ± 2 cM)
TreeFam: TF101133
Sequences
Representative Sequences Length Strain/Species Flank
genomic ENSMUSG00000026605 Ensembl Gene Model | MGI Sequence Detail 47471 C57BL/6J ± Kb
transcript NM_001081363 RefSeq | MGI Sequence Detail 11130 -
polypeptide NP_001074832 RefSeq | MGI Sequence Detail 2997 -
For the selected sequences
All sequences(37)
Alleles
and
phenotypes 		All alleles(12) : Gene trapped(12)
Polymorphisms RFLP(1) SNPs within 2kb(200 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (30 annotations)
Process heart development, negative regulation of apoptosis...
Component centrosome, chromosome, centromeric region...
Function protein binding
External Resources: FuncBase
Expression Literature Summary: (2 records)
Data Summary: Assays (3)    Results (30)    Tissues (20)    Images (10)
Theiler Stages: 13,15,21,23,24,26,28
  Assay Type Assays   Results
      Immunohistochemistry 1   9
      Northern blot 2   21
cDNA source data(145)
External Resources: Allen Brain Atlas  GEO  ArrayExpress 
Molecular
reagents 		All nucleic(147) Genomic(1) cDNA(145) Primer pair(1) Antibodies(1)
Microarray probesets(3)
Other database
links
Ensembl Gene Model ENSMUSG00000026605
DoTS DT.101380922, DT.103567373, DT.489527
Consensus CDS Project CCDS35820.1
UniGene 129746
DFCI TC1597488, TC1609295
NIA Mouse Gene Index U022190
Entrez Gene 108000
International Mouse Knockout Project Status Cenpf
Protein
domains
InterPro ID Description
IPR018302 Centromere protein Cenp-F, Rb protein-binding domain
IPR018463 Centromere protein Cenp-F, N-terminal
IPR019513 Centromere protein Cenp-F, leucine-rich repeat-containing domain
References
(Earliest) J:124853 Zhu X et al., "The C terminus of mitosin is essential for its nuclear localization, centromere/kinetochore targeting, and dimerization." J Biol Chem 1995 Aug 18;270(33):19545-50
(Latest) J:140958 Pooley RD et al., "Murine CENPF interacts with syntaxin 4 in the regulation of vesicular transport." J Cell Sci 2008 Oct 15;121(Pt 20):3413-21
All references(25)
Other
accession IDs 		MGI:1344369, MGI:1915046, MGI:2138210
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support. 		last database update
02/06/2010
MGI_4.32
Web browser compatibility 		The Jackson Laboratory