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Wnt2b Gene Detail
 Symbol
Name
ID
Wnt2b
wingless related MMTV integration site 2b
MGI:1261834


Nomenclature History
Synonyms Wnt13
Genetic Map
Chromosome 3
49.0 cM
Detailed Genetic Map ± 1 cM
 
Mapping data( 2)

Sequence Map
Chr3:104747723-104764627 bp, - strand
(From NCBI annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Wnt2b ± 2 cM)
Protein SuperFamily: int-1 transforming protein
TreeFam: TF105310
Sequences
Representative Sequences Length Strain/Species Flank
genomic 22414 NCBI Gene Model | MGI Sequence Detail 16905 C57BL/6J ± Kb
transcript NM_009520 RefSeq | MGI Sequence Detail 3573 C57BL/6
polypeptide O70283 UniProt | EBI | MGI Sequence Detail 389 Not Applicable
For the selected sequences
All sequences(16)
Alleles
and
phenotypes
All alleles(3) : Targeted, knock-out(2) Targeted, other(1)
Mice homozygous for a knock-out allele exhibit no discernable phenotype.
Polymorphisms SNPs within 2kb(79 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process cell-cell signaling, lung induction...
Component extracellular region, proteinaceous extracellular matrix...
Function receptor binding, signal transducer activity...
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression Literature Summary: (65 records)
Data Summary: Assays (20)    Results (309)    Tissues (175)    Images (84)
Theiler Stages: 1,2,3,4,5,8,9,10,11,12,13,14,15,16,17,19,20,21,22,23,24,25,26,28
  Assay Type Assays   Results
      RT-PCR 6   31
      RNA in situ 13   276
      RNase protection 1   2
cDNA source data(12)
External Resources: Allen Brain Atlas  GENSAT  GEO  ArrayExpress 
Molecular
reagents
All nucleic(28) Genomic(1) cDNA(14) Primer pair(8) Other(5)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000027840
DoTS DT.55110411
Consensus CDS Project CCDS17706.1
UniGene 10740
DFCI TC1587834
NIA Mouse Gene Index U024469
Entrez Gene 22414
International Mouse Knockout Project Status Wnt2b
Protein
domains
InterPro ID Description
IPR005816 Secreted growth factor Wnt protein
IPR005817 Wnt superfamily
IPR009140 Wnt-2 protein
IPR018161 Secreted growth factor Wnt protein, conserved site
Graphical View of Protein Domain Structure
References
(Earliest) J:47698 Zakin LD et al., "Structure and expression of Wnt13, a novel mouse Wnt2 related gene." Mech Dev 1998 Apr;73(1):107-16
(Latest) J:155332 Fotaki V et al., "Loss of Wnt8b has no overt effect on hippocampus development but leads to altered Wnt gene expression levels in dorsomedial telencephalon." Dev Dyn 2010 Jan;239(1):284-96
All references(70)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
02/06/2010
MGI_4.32
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The Jackson Laboratory