Symbol
Name
ID
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Nfkb2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100
MGI:1099800
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Nomenclature History
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Synonyms
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NF kappaB2, p52
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Genetic Map
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Sequence Map
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Mammalian
homology
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Sequences
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All sequences(42)
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Alleles
and
phenotypes
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All alleles(7) :
Targeted, knock-out(5)
Chemically induced(2)
| Homozygotes for targeted null mutations exhibit gastric hyperplasia, enlarged lymph nodes, enhanced cytokine production by activated T cells, absence of Peyer's patches, increased susceptibility to Leishmania major, and early postnatal mortality. |
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Polymorphisms
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PCR(1)
SNPs within 2kb(27 from dbSNP Build 128)
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Gene Ontology
(GO)
classifications
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Expression
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Literature Summary: (9 records)
Data Summary:
Assays (3)
Results (32)
Tissues (30)
Images (2)
Theiler Stages: 2,3,4,5,17,18,21,28
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Assay Type |
Assays |
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Results |
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RT-PCR |
1 |
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15 |
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RNA in situ |
2 |
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17 |
cDNA source data(70)
External Resources:
Allen Brain Atlas
GEO
ArrayExpress
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Molecular
reagents
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All nucleic(85)
Genomic(12)
cDNA(70)
Primer pair(2)
Other(1)
Microarray probesets(2)
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Other database
links
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Protein
domains
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Graphical View
of Protein Domain Structure
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References
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(Earliest)
J:54118
Verma IM et al.,
"Rel/NF-kappa B/I kappa B family: intimate tales of association and dissociation."
Genes Dev 1995 Nov 15;9(22):2723-35
(Latest)
J:154633
Yao Z et al.,
"NF-kappaB p100 limits TNF-induced bone resorption in mice by a TRAF3-dependent mechanism."
J Clin Invest 2009 Oct;119(10):3024-34
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All references(81)
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Analysis Tools
MGI BioMart
