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Acaa2 Gene Detail
 Symbol
Name
ID
Acaa2
acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase)
MGI:1098623

Nomenclature History
Synonyms 0610011L04Rik, D18Ertd240e
Genetic Map
Chromosome 18
45.0 cM
Detailed Genetic Map ± 1 cM
 
Mapping data( 4)

Sequence Map
Chr18:74938866-74965861 bp, + strand
(From NCBI annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Acaa2 ± 2 cM)
Protein SuperFamily: acetyl-CoA acetyltransferase
TreeFam: TF105696
Sequences
Representative Sequences Length Strain/Species Flank
genomic 52538 NCBI Gene Model | MGI Sequence Detail 26996 C57BL/6J ± Kb
transcript NM_177470 RefSeq | MGI Sequence Detail 1500 C57BL/6
polypeptide Q8BWT1 UniProt | EBI | MGI Sequence Detail 397 Not Applicable
For the selected sequences
All sequences(25)
Alleles
and
phenotypes 		All alleles(5) : Gene trapped(5)
Polymorphisms SNPs within 2kb(86 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (10 annotations)
Process fatty acid metabolic process, lipid metabolic process...
Component mitochondrial inner membrane, mitochondrion...
Function acetyl-CoA C-acyltransferase activity, acyltransferase activity...
External Resources: FuncBase
Expression Literature Summary: (1 records)
Data Summary: Assays (1)    Results (94)    Tissues (94)    Images (21)
Theiler Stages: 22
  Assay Type Assays   Results
      RNA in situ 1   94
cDNA source data(357)
External Resources: Allen Brain Atlas  GEO  ArrayExpress 
Molecular
reagents 		All nucleic(359) cDNA(357) Primer pair(2)
Microarray probesets(3)
Pathways
fatty acid β-oxidation I
fatty acid β-oxidation II (core pathway)
Other database
links
EC 2.3.1.16
Ensembl Gene Model ENSMUSG00000036880
DoTS DT.101370397, DT.99868467
Consensus CDS Project CCDS29342.1
UniGene 245724
DFCI TC1573252
NIA Mouse Gene Index U018898
Entrez Gene 52538
International Mouse Knockout Project Status Acaa2
Protein
domains
InterPro ID Description
IPR002155 Thiolase
IPR016038 Thiolase-like, subgroup
IPR016039 Thiolase-like
IPR020610 Thiolase, active site
IPR020613 Thiolase, conserved site
IPR020615 Thiolase, acyl-enzyme intermediate active site
IPR020616 Thiolase, N-terminal
IPR020617 Thiolase, C-terminal
Graphical View of Protein Domain Structure
References
(Earliest) J:60984 Ko MS et al., "Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development." Development 2000 Apr;127(8):1737-49
(Latest) J:151002 Pagliarini DJ et al., "A mitochondrial protein compendium elucidates complex I disease biology." Cell 2008 Jul 11;134(1):112-23
All references(11)
Other
accession IDs 		MGI:1915593, MGI:2147202, MGI:2147205
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
02/06/2010
MGI_4.32
Web browser compatibility 		The Jackson Laboratory