Symbol
Name
ID
|
|
|
Synonyms
|
ATF-2, CRE-BP, Creb2, D130078H02Rik, mXBP
|
|
Genetic Map
|
|
Chromosome 2
|
Syntenic
|
|
|
|
Mapping data(
2)
|
|
|
|
Sequence Map
|
|
Mammalian
homology
|
|
|
Sequences
|
All sequences(61)
|
Alleles
and
phenotypes
|
All alleles(57) :
Targeted, knock-out(3)
Targeted, other(2)
Gene trapped(51)
Transgenic(1)
| Homozygous mutation of this gene results in increased postnatal lethality, skeletal development defects, runting, decreased hearing, inner ear and brain abnormalities, hyperactivity, and ataxia. |
Phenotype Images (1)
|
|
Polymorphisms
|
SNPs within 2kb(126 from dbSNP Build 128)
|
Gene Ontology
(GO)
classifications
|
|
|
Expression
|
Literature Summary: (14 records)
Data Summary:
Assays (8)
Results (94)
Tissues (54)
Images (8)
Theiler Stages: 2,3,4,5,14,15,17,20,21,22,24,26,28
| |
Assay Type |
Assays |
|
Results |
| |
RT-PCR |
2 |
|
17 |
| |
RNA in situ |
5 |
|
75 |
| |
Northern blot |
1 |
|
2 |
cDNA source data(195)
External Resources:
Allen Brain Atlas
GEO
|
Molecular
reagents
|
All nucleic(205)
Genomic(2)
cDNA(201)
Primer pair(2)
Microarray probesets(5)
|
Other database
links
|
| Ensembl Gene Model |
ENSMUSG00000027104 |
| DoTS |
DT.101136302, DT.101381516, DT.101381517, DT.110698614, DT.110698636, DT.110698643, DT.488504, DT.91302302, DT.91342314, DT.91375433 |
| UniGene |
209903 |
| DFCI |
TC1576367, TC1583588, TC1588023, TC1594955, TC1606143, TC1715346 |
| NIA Mouse Gene Index |
U022749 |
| Entrez Gene |
11909 |
| VEGA Gene Model |
OTTMUSG00000013179 |
| International Mouse Knockout Project Status |
Atf2 |
|
Protein
domains
|
| InterPro ID |
Description |
| IPR004827 |
Basic-leucine zipper (bZIP) transcription factor |
| IPR007087 |
Zinc finger, C2H2-type |
| IPR011616 |
bZIP transcription factor, bZIP-1 |
| IPR015880 |
Zinc finger, C2H2-like |
| IPR016378 |
Transcription factor, cyclic AMP-dependent |
Graphical View
of Protein Domain Structure
|
|
References
|
(Earliest)
J:40530
Hai TW et al.,
"Transcription factor ATF cDNA clones: an extensive family of leucine zipper proteins able to selectively form DNA-binding heterodimers [published erratum appears in Genes Dev 1990 Apr;4(4):682]"
Genes Dev 1989 Dec;3(12B):2083-90
(Latest)
J:153077
Satake H et al.,
"Spatio-temporal expression of activating transcription factor 5 in the skeletal development of mouse limb."
Dev Growth Differ 2009 Sep;51(7):669-76
|
All references(51)
|
Other
accession IDs
|
MGD-MRK-23723, MGD-MRK-38394, MGI:2139537, MGI:2441951, MGI:2678345
|
|
