Symbol
Name
ID
|
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Synonyms
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Prop-1, prophet of Pit-1, prophet of Pit1
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Genetic Map
|
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Sequence Map
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Mammalian
homology
|
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Sequences
|
All sequences(12)
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Alleles
and
phenotypes
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All alleles(3) :
Targeted, knock-out(2)
Spontaneous(1)
| Homozygotes for a spontaneous mutation exhibit severe proportional dwarfism, hypothyroidism, and sterility. Mutants fail to develop the anterior pituitary cells that secrete growth hormone, prolactin, and thyroid stimulating hormone. |
Associated Human Diseases (1)
Alleles Annotated to Human Diseases (1)
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Polymorphisms
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SNPs within 2kb(4 from dbSNP Build 128)
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Gene Ontology
(GO)
classifications
|
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Expression
|
Literature Summary: (24 records)
Data Summary:
Assays (4)
Results (23)
Tissues (12)
Theiler Stages: 15,17,18,19,20,21,22,23,24,25,28
| |
Assay Type |
Assays |
|
Results |
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RT-PCR |
1 |
|
2 |
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RNA in situ |
2 |
|
19 |
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Immunohistochemistry |
1 |
|
2 |
cDNA source data(1)
External Resources:
Allen Brain Atlas
GEO
|
Molecular
reagents
|
All nucleic(18)
Genomic(14)
cDNA(1)
Primer pair(1)
Other(2)
Antibodies(1)
Microarray probesets(2)
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Other database
links
|
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Protein
domains
|
Graphical View
of Protein Domain Structure
|
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References
|
(Earliest)
J:64260
Schaible RH et al.,
"df - Ames dwarf"
Mouse News Lett 1961;25():35
(Latest)
J:147778
Bilodeau S et al.,
"Distinct developmental roles of cell cycle inhibitors p57Kip2 and p27Kip1 distinguish pituitary progenitor cell cycle exit from cell cycle reentry of differentiated cells."
Mol Cell Biol 2009 Apr;29(7):1895-908
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All references(122)
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Other
accession IDs
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MGD-MRK-38375, MGD-MRK-8832
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