About   Help   FAQ
Tour our new Quick Search
Wnt8a Gene Detail
 Symbol
Name
ID
Wnt8a
wingless-related MMTV integration site 8A
MGI:107924

Nomenclature History
Synonyms Stra11
Genetic Map
Chromosome 18
cytoband B3
 
Mapping data( 2)
Sequence Map
Chr18:34701967-34707927 bp, + strand
(From NCBI annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
Protein SuperFamily: int-1 transforming protein
TreeFam: TF105310
Sequences
Representative Sequences Length Strain/Species Flank
genomic 20890 NCBI Gene Model | MGI Sequence Detail 5961 C57BL/6J ± Kb
transcript NM_009290 RefSeq | MGI Sequence Detail 1519 C57BL/6
polypeptide Q64527 UniProt | EBI | MGI Sequence Detail 354 Not Applicable
For the selected sequences
All sequences(14)
Alleles
and
phenotypes 		All alleles(1) : Targeted, knock-out(1)
Polymorphisms SNPs within 2kb(31 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (8 annotations)
Process multicellular organismal development, Wnt receptor signaling pathway...
Component extracellular region, proteinaceous extracellular matrix...
Function signal transducer activity
External Resources: FuncBase
Expression Literature Summary: (37 records)
Data Summary: Assays (11)    Results (179)    Tissues (156)    Images (27)
Theiler Stages: 5,8,9,11,12,13,15,17,19,20,21,22,23,24,26,28
  Assay Type Assays   Results
      RT-PCR 3   9
      RNA in situ 7   168
      RNase protection 1   2
cDNA source data(8)
External Resources: Allen Brain Atlas  GEO  ArrayExpress 
Molecular
reagents 		All nucleic(18) cDNA(10) Primer pair(6) Other(2)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000012282
DoTS DT.40157754, DT.94226319
Consensus CDS Project CCDS29129.1
UniGene 558
DFCI TC1595915
NIA Mouse Gene Index U018541
Entrez Gene 20890
International Mouse Knockout Project Status Wnt8a
Protein
domains
InterPro ID Description
IPR005816 Secreted growth factor Wnt protein
IPR005817 Wnt superfamily
IPR013301 Wnt-8 protein
IPR018161 Secreted growth factor Wnt protein, conserved site
Graphical View of Protein Domain Structure
References
(Earliest) J:28316 Bouillet P et al., "Efficient cloning of cDNAs of retinoic acid-responsive genes in P19 embryonal carcinoma cells and characterization of a novel mouse gene, Stra1 (mouse LERK-2/Eplg2)." Dev Biol 1995 Aug;170(2):420-33
(Latest) J:155074 Agalliu D et al., "Motor neurons with axial muscle projections specified by Wnt4/5 signaling." Neuron 2009 Mar 12;61(5):708-20
All references(40)
Other
accession IDs 		MGD-MRK-36504
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support. 		last database update
02/06/2010
MGI_4.32
Web browser compatibility 		The Jackson Laboratory