About   Help   FAQ
Apbb1 Gene Detail
 Symbol
Name
ID
Apbb1
amyloid beta (A4) precursor protein-binding, family B, member 1
MGI:107765


Nomenclature History
Synonyms Fe65, Rir
Genetic Map
Chromosome 7
46.6 cM
Detailed Genetic Map ± 1 cM
 
Mapping data( 5)

Sequence Map
Chr7:112707000-112729735 bp, - strand
(From Ensembl annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Apbb1 ± 2 cM)
TreeFam: TF314331
Sequences
Representative Sequences Length Strain/Species Flank
genomic ENSMUSG00000037032 Ensembl Gene Model | MGI Sequence Detail 22736 C57BL/6J ± Kb
transcript NM_009685 RefSeq | MGI Sequence Detail 2593 C57BL/6
polypeptide Q9QXJ1 UniProt | EBI | MGI Sequence Detail 710 Not Applicable
For the selected sequences
All sequences(29)
Alleles
and
phenotypes
All alleles(4) : Targeted, knock-out(4)
Polymorphisms PCR(1) SNPs within 2kb(38 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications(28)
Process actin filament-based movement, apoptosis...
Component cytoplasm, membrane...
Function beta-amyloid binding, histone acetyltransferase binding...
External Resources: MouseFunc
Expression Literature Summary: (5 records)
Data Summary: Assays (1)    Results (92)    Tissues (92)    Images (11)
Theiler Stages: 22
  Assay Type Assays   Results
      RNA in situ 1   92
cDNA source data(112)
External Resources: Allen Brain Atlas  GEO 
Molecular
reagents
All nucleic(113) cDNA(112) Primer pair(1)
Microarray probesets(3)
Other database
links
Ensembl Gene Model ENSMUSG00000037032
DoTS DT.101736491, DT.101736492, DT.491464, DT.99864594
UniGene 38469
DFCI TC1573997, TC1588669, TC1591584
NIA Mouse Gene Index U029038
Entrez Gene 11785
International Mouse Knockout Project Status Apbb1
Protein
domains
InterPro ID Description
IPR001202 WW/Rsp5/WWP
IPR006020 Phosphotyrosine interaction domain
IPR011993 Pleckstrin homology-type
Graphical View of Protein Domain Structure
References
(Earliest) J:37182 Simeone A et al., "Expression of the neuron-specific FE65 gene marks the development of embryo ganglionic derivatives." Dev Neurosci 1994;16(1-2):53-60
(Latest) J:147140 Stante M et al., "Fe65 is required for Tip60-directed histone H4 acetylation at DNA strand breaks." Proc Natl Acad Sci U S A 2009 Mar 31;106(13):5093-8
All references(27)
Other
accession IDs
MGD-MRK-36342

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/20/2009
MGI_4.31
Web browser compatibility
The Jackson Laboratory