Symbol
Name
ID
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Synonyms
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CD195, Cmkbr5
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Genetic Map
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Sequence Map
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Mammalian
homology
|
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Sequences
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All sequences(31)
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Alleles
and
phenotypes
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All alleles(5) :
Targeted, knock-out(3)
Targeted, other(2)
| Mice that are homozygous for null alleles have leukocytes with defective migration and adhesion, are more susceptibility to fungal & bacterial infections, have increased length of allograft survival, and have decreased susceptibility to endotoxin shock. |
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Polymorphisms
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RFLP(1)
SNPs within 2kb(110 from dbSNP Build 128)
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Gene Ontology
(GO)
classifications
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Expression
|
Literature Summary: (3 records)
Data Summary:
Assays (2)
Results (51)
Tissues (50)
Images (2)
Theiler Stages: 13,20,23,28
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Assay Type |
Assays |
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Results |
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RT-PCR |
1 |
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46 |
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RNase protection |
1 |
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5 |
cDNA source data(44)
External Resources:
Allen Brain Atlas
GENSAT
GEO
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Molecular
reagents
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All nucleic(49)
Genomic(2)
cDNA(44)
Primer pair(1)
Other(2)
Microarray probesets(5)
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Other database
links
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Protein
domains
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Graphical View
of Protein Domain Structure
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References
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(Earliest)
J:32263
Boring L et al.,
"Molecular cloning and functional expression of murine JE (monocyte chemoattractant protein 1) and murine macrophage inflammatory protein 1alpha receptors: evidence for two closely linked C-C chemokine receptors on chromosome 9."
J Biol Chem 1996 Mar 29;271(13):7551-8
(Latest)
J:153059
Passos GF et al.,
"Role of the macrophage inflammatory protein-1alpha/CC chemokine receptor 5 signaling pathway in the neuroinflammatory response and cognitive deficits induced by beta-amyloid peptide."
Am J Pathol 2009 Oct;175(4):1586-97
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All references(119)
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Other
accession IDs
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MGD-MRK-35643
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