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Ppp3r2 Gene Detail
 Symbol
Name
ID
Ppp3r2
protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type II)
MGI:107171

Nomenclature History
Synonyms PP2B beta 2
Genetic Map
Chromosome 4
cytoband B3
 
Mapping data( 1)
Sequence Map
Chr4:49691619-49694896 bp, - strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
Protein SuperFamily: calmodulin
TreeFam: TF105558
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000006951 VEGA Gene Model | MGI Sequence Detail 3278 C57BL/6J ± Kb
transcript NM_001004025 RefSeq | MGI Sequence Detail 2985 C57BL/6
polypeptide Q63811 UniProt | EBI | MGI Sequence Detail 179 Not Applicable
For the selected sequences
All sequences(16)
Alleles
and
phenotypes 		All alleles(1) : Targeted, knock-out(1)
Polymorphisms SNPs within 2kb(57 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (6 annotations)
Process defense response, glycogen metabolic process...
Function calcium ion binding, calcium-dependent protein serine/threonine phosphatase activity...
External Resources: FuncBase
Expression Literature Summary: (1 records)
Data Summary: Assays (1)    Results (2)    Tissues (2)    Images (1)
Theiler Stages: 21,24
  Assay Type Assays   Results
      RT-PCR 1   2
cDNA source data(40)
External Resources: Allen Brain Atlas  GEO  ArrayExpress 
Molecular
reagents 		All nucleic(42) Genomic(1) cDNA(40) Primer pair(1)
Microarray probesets(1)
Other database
links
Ensembl Gene Model ENSMUSG00000028310
DoTS DT.94162542
Consensus CDS Project CCDS18179.1
UniGene 46125
DFCI TC1580052
Entrez Gene 19059
VEGA Gene Model OTTMUSG00000006951
International Mouse Knockout Project Status Ppp3r2
Protein
domains
InterPro ID Description
IPR002048 Calcium-binding EF-hand
IPR011992 EF-hand-like domain
IPR018247 EF-Hand 1, calcium-binding site
IPR018248 EF-Hand domain
IPR018249 EF-HAND 2
Graphical View of Protein Domain Structure
References
(Earliest) J:2181 Ueki K et al., "Structure and expression of two isoforms of the murine calmodulin-dependent protein phosphatase regulatory subunit (calcineurin B)." Biochem Biophys Res Commun 1992 Aug 31;187(1):537-43
(Latest) J:119549 Yang XY et al., "Dosage-dependent transcriptional regulation by the calcineurin/NFAT signaling in developing myocardium transition." Dev Biol 2007 Mar 15;303(2):825-37
All references(6)
Other
accession IDs 		MGD-MRK-35632
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
02/06/2010
MGI_4.32
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