About   Help   FAQ
Tour our new Quick Search
Adipoq Gene Detail
 Symbol
Name
ID
Adipoq
adiponectin, C1Q and collagen domain containing
MGI:106675

Nomenclature History
Synonyms Acdc, Acrp30, adipo, adiponectin, apM1, APN, GBP28
Genetic Map
Chromosome 16
16.0 cM, cytoband B3-B4
Detailed Genetic Map ± 1 cM
 
Mapping data( 3)

Sequence Map
Chr16:23146692-23157813 bp, + strand
(From Ensembl annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Adipoq ± 2 cM)
Protein SuperFamily: complement subcomponent C1q chain A
TreeFam: TF329591
Sequences
Representative Sequences Length Strain/Species Flank
genomic ENSMUSG00000022878 Ensembl Gene Model | MGI Sequence Detail 11122 C57BL/6J ± Kb
transcript NM_009605 RefSeq | MGI Sequence Detail 1233 C57BL/6
polypeptide Q60994 UniProt | EBI | MGI Sequence Detail 247 Not Applicable
For the selected sequences
All sequences(21)
Alleles
and
phenotypes 		All alleles(8) : Targeted, knock-out(6) Targeted, other(2)
Homozygotes for targeted null mutations exhibit increased beta-oxidation in muscle and liver, impaired free fatty acid clearance, and moderate insulin resistance. Heterozygotes show mild insulin resistance.
Polymorphisms SNPs within 2kb(57 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (27 annotations)
Process brown fat cell differentiation, fatty acid beta-oxidation...
Component endoplasmic reticulum, extracellular region...
Function hormone activity, protein binding...
External Resources: FuncBase
Expression Literature Summary: (9 records)
Data Summary: Assays (7)    Results (38)    Tissues (25)    Images (3)
Theiler Stages: 10,18,21,23,25,28
  Assay Type Assays   Results
      Western blot 1   2
      RT-PCR 3   27
      Northern blot 3   9
cDNA source data(69)
External Resources: Allen Brain Atlas  GEO  ArrayExpress 
Molecular
reagents 		All nucleic(74) Genomic(1) cDNA(71) Primer pair(2) Antibodies(1)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000022878
DoTS DT.536006
Consensus CDS Project CCDS28075.1
UniGene 3969
PDB 1C28, 1C3H
DFCI TC1578928
NIA Mouse Gene Index U016957
Entrez Gene 11450
International Mouse Knockout Project Status Adipoq
Protein
domains
InterPro ID Description
IPR001073 Complement C1q protein
IPR008160 Collagen triple helix repeat
IPR008983 Tumour necrosis factor-like
Graphical View of Protein Domain Structure
References
(Earliest) J:32963 Scherer PE et al., "A novel serum protein similar to C1q, produced exclusively in adipocytes." J Biol Chem 1995 Nov 10;270(45):26746-9
(Latest) J:154402 Halberg N et al., "Systemic fate of the adipocyte-derived factor adiponectin." Diabetes 2009 Sep;58(9):1961-70
All references(93)
Other
accession IDs 		MGD-MRK-35134
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support. 		last database update
02/06/2010
MGI_4.32
Web browser compatibility 		The Jackson Laboratory