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Nfkbib Gene Detail
 Symbol
Name
ID
Nfkbib
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
MGI:104752

Nomenclature History
Synonyms IKappaBbeta, IkB, MGC:36057
Genetic Map
Chromosome 7
cytoband A3-B3
 
Mapping data( 3)
Sequence Map
Chr7:29543270-29552531 bp, - strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
Protein SuperFamily: NF-kappaB inhibitor
TreeFam: TF320166
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000016845 VEGA Gene Model | MGI Sequence Detail 9262 C57BL/6J ± Kb
transcript NM_010908 RefSeq | MGI Sequence Detail 1945 C57BL/6
polypeptide Q60778 UniProt | EBI | MGI Sequence Detail 359 Not Applicable
For the selected sequences
All sequences(26)
Alleles
and
phenotypes 		All alleles(6) : Targeted, knock-out(1) Gene trapped(5)
Polymorphisms SNPs within 2kb(52 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (2 annotations)
Component cytoplasm, nucleus...
External Resources: FuncBase
Expression Literature Summary: (4 records)
cDNA source data(5)
External Resources: Allen Brain Atlas  GEO  ArrayExpress 
Molecular
reagents 		All nucleic(7) Genomic(1) cDNA(5) Other(1)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000030595
DoTS DT.101382542, DT.111009960, DT.492670
Consensus CDS Project CCDS21054.1
PDB 1K3Z, 1OY3
DFCI TC1578970, TC1592802
NIA Mouse Gene Index U028331
Entrez Gene 18036
VEGA Gene Model OTTMUSG00000016845
International Mouse Knockout Project Status Nfkbib
Protein
domains
InterPro ID Description
IPR002110 Ankyrin repeat
IPR015681 Nuclear Factor kappaB inhibitor
IPR020683 Ankyrin repeat-containing domain
Graphical View of Protein Domain Structure
References
(Earliest) J:23294 Thompson JE et al., "I kappa B-beta regulates the persistent response in a biphasic activation of NF-kappa B." Cell 1995 Feb 24;80(4):573-82
(Latest) J:136288 Molotski N et al., "Teratogen-induced distortions in the classical NF-kappaB activation pathway: correlation with the ability of embryos to survive teratogenic stress." Toxicol Appl Pharmacol 2008 Jun 1;229(2):197-205
All references(23)
Other
accession IDs 		MGD-MRK-28043
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
02/06/2010
MGI_4.32
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