Symbol
Name
ID
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Synonyms
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9530021D13Rik, Nr1f1
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Genetic Map
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Sequence Map
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Mammalian
homology
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Sequences
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All sequences(35)
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Alleles
and
phenotypes
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All alleles(6) :
Targeted, knock-out(1)
Targeted, other(2)
Gene trapped(1)
Spontaneous(1)
Chemically induced(1)
| Homozygotes for null mutations exhibit ataxia, cerebellar dysgenesis, impaired Purkinje and granule cell development, olfactory defects, hypoalphalipoproteinemia, and death around 4 weeks. Heterozygotes show slow Purkinje cell dedritic atrophy and loss. |
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Polymorphisms
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RFLP(1)
SNPs within 2kb(4503 from dbSNP Build 128)
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Gene Ontology
(GO)
classifications
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Expression
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Literature Summary: (28 records)
Data Summary:
Assays (13)
Results (295)
Tissues (189)
Images (28)
Theiler Stages: 2,3,4,5,17,18,21,22,23,25,28
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Assay Type |
Assays |
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Results |
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RT-PCR |
3 |
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62 |
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RNA in situ |
8 |
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222 |
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Northern blot |
2 |
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11 |
cDNA source data(26)
External Resources:
GENSAT
GEO
|
Molecular
reagents
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All nucleic(43)
Genomic(11)
cDNA(26)
Primer pair(4)
Other(2)
Microarray probesets(4)
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Other database
links
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Protein
domains
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| InterPro ID |
Description |
| IPR000536 |
Nuclear hormone receptor, ligand-binding, core |
| IPR001628 |
Zinc finger, nuclear hormone receptor-type |
| IPR001723 |
Steroid hormone receptor |
| IPR003079 |
Nuclear receptor ROR |
| IPR008946 |
Nuclear hormone receptor, ligand-binding |
| IPR013088 |
Zinc finger, NHR/GATA-type |
Graphical View
of Protein Domain Structure
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References
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(Earliest)
J:13140
SIDMAN RL et al.,
"Staggerer, a new mutation in the mouse affecting the cerebellum."
Science 1962 Aug 24;137():610-2
(Latest)
J:152678
Maricich SM et al.,
"Atoh1-lineal neurons are required for hearing and for the survival of neurons in the spiral ganglion and brainstem accessory auditory nuclei."
J Neurosci 2009 Sep 9;29(36):11123-33
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All references(168)
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Other
accession IDs
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MGD-MRK-14383, MGD-MRK-26101, MGI:2442931, MGI:3054678
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