Symbol
Name
ID
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Synonyms
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MAT, matrilysin
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Genetic Map
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Sequence Map
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Mammalian
homology
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Sequences
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All sequences(22)
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Alleles
and
phenotypes
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All alleles(1) :
Targeted, knock-out(1)
| Mice homozygous for a knock-out allele exhibit increased sensitivity to induced colitis and corneal wound neovascularization, decreased sensitivity to myocardial infarction and pancreatic duct ligation, impaired tracheal wound healing, and altered tumor susceptibility. |
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Polymorphisms
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RFLP(1)
SNPs within 2kb(68 from dbSNP Build 128)
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Gene Ontology
(GO)
classifications
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Expression
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Literature Summary: (16 records)
Data Summary:
Assays (6)
Results (58)
Tissues (53)
Images (4)
Theiler Stages: 17,19,20,21,22,23,26,28
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Assay Type |
Assays |
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Results |
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RT-PCR |
6 |
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58 |
cDNA source data(15)
External Resources:
Allen Brain Atlas
GEO
ArrayExpress
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Molecular
reagents
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All nucleic(28)
Genomic(7)
cDNA(16)
Primer pair(5)
Microarray probesets(2)
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Other database
links
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Protein
domains
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| InterPro ID |
Description |
| IPR001818 |
Peptidase M10A/M12B, matrixin/adamalysin |
| IPR002477 |
Peptidoglycan binding-like |
| IPR006026 |
Peptidase, metallopeptidases |
Graphical View
of Protein Domain Structure
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References
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(Earliest)
J:26885
Wilson CL et al.,
"The metalloproteinase matrilysin is preferentially expressed by epithelial cells in a tissue-restricted pattern in the mouse."
Mol Biol Cell 1995 Jul;6(7):851-69
(Latest)
J:155734
Ogden SR et al.,
"Matrix metalloproteinase-7 and premalignant host responses in Helicobacter pylori-infected mice."
Cancer Res 2010 Jan 1;70(1):30-5
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All references(63)
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Other
accession IDs
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MGD-MRK-24057
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Analysis Tools
MGI BioMart
