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Reln Gene Detail
 Symbol
Name
ID
Reln
reelin
MGI:103022


Nomenclature History
Genetic Map
Chromosome 5
8.0 cM, cytoband A3-B1
Detailed Genetic Map ± 1 cM
 
Mapping data( 29)

Sequence Map
Chr5:21390272-21850520 bp, - strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Reln ± 2 cM)
TreeFam: TF106479
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000030584 VEGA Gene Model | MGI Sequence Detail 460249 C57BL/6J ± Kb
transcript NM_011261 RefSeq | MGI Sequence Detail 11702 C57BL/6
polypeptide Q60841 UniProt | EBI | MGI Sequence Detail 3461 Not Applicable
For the selected sequences
All sequences(37)
Alleles
and
phenotypes
All alleles(14) : Targeted, other(2) Transgenic(1) Spontaneous(7) Chemically induced(4)
Phenotype Images (2)  
Polymorphisms All PCR and RFLP(7) : PCR(2) RFLP(5) SNPs within 2kb(3547 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications(31)
Process axon guidance, brain development...
Component cytoplasm, dendrite...
Function calcium ion binding, hydrolase activity...
External Resources: MouseFunc
Expression Literature Summary: (196 records)
Data Summary: Assays (21)    Results (158)    Tissues (124)    Images (53)
Theiler Stages: 15,19,20,21,22,23,25,26,28
  Assay Type Assays   Results
      RT-PCR 5   10
      RNA in situ 9   133
      Immunohistochemistry 3   8
      Northern blot 4   7
cDNA source data(112)
External Resources: Allen Brain Atlas  GEO 
Molecular
reagents
All nucleic(155) Genomic(24) cDNA(117) Primer pair(10) Other(4) Antibodies(3)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000042453
DoTS DT.486700, DT.91310973, DT.91311417, DT.91356456, DT.91370906, DT.91395221
UniGene 425236
PDB 2DDU, 2E26
DFCI TC1578722, TC1595889, TC1596615, TC1672277
NIA Mouse Gene Index U025970
Entrez Gene 19699
VEGA Gene Model OTTMUSG00000030584
International Mouse Knockout Project Status Reln
Protein
domains
InterPro ID Description
IPR000742 EGF-like, type 3
IPR002861 Reeler domain
IPR006210 EGF-like
IPR011040 Neuraminidase
IPR013032 EGF-like region, conserved site
IPR013111 EGF, extracellular
Graphical View of Protein Domain Structure
References
(Earliest) J:13038 Falconer DS, "Two new mutants, "trembler" and "reeler," with neurological actions in the house mouse." J Genet 1951;50():192-201
(Latest) J:153209 Tissir F et al., "DeltaNp73 regulates neuronal survival in vivo." Proc Natl Acad Sci U S A 2009 Sep 29;106(39):16871-6
All references(416)
Other
accession IDs
MGD-MRK-13895, MGD-MRK-23859

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/20/2009
MGI_4.31
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The Jackson Laboratory