Symbol
Name
ID
|
|
|
Synonyms
|
IDX-1, IPF-1, Ipf1, Mody4, pdx-1, STF-1
|
|
Genetic Map
|
|
|
Sequence Map
|
|
Mammalian
homology
|
|
|
Sequences
|
All sequences(16)
|
Alleles
and
phenotypes
|
All alleles(10) :
Targeted, knock-out(3)
Targeted, other(6)
Gene trapped(1)
| Mice homozygous for a knock-out allele exhibit postnatal lethality, abnormal pancreatic and liver development, and increased plasma glucose levels. Mice heterozygous for a knock-out allele exhibit abnormal pancreatic development and abnormal glucose homeostasis. |
Associated Human Diseases (4)
Alleles Annotated to Human Diseases (3)
|
|
Polymorphisms
|
All PCR and RFLP(2) :
PCR(1)
RFLP(1)
SNPs within 2kb(2 from dbSNP Build 128)
|
Gene Ontology
(GO)
classifications
|
|
|
Expression
|
Literature Summary: (182 records)
Data Summary:
Assays (38)
Results (369)
Tissues (104)
Images (78)
Theiler Stages: 11,12,13,14,15,16,17,18,19,20,21,22,23,24,25,26,28
| |
Assay Type |
Assays |
|
Results |
| |
RT-PCR |
15 |
|
272 |
| |
RNA in situ |
5 |
|
18 |
| |
Immunohistochemistry |
16 |
|
70 |
| |
Northern blot |
2 |
|
9 |
cDNA source data(12)
External Resources:
Allen Brain Atlas
GEO
ArrayExpress
|
Molecular
reagents
|
All nucleic(30)
Genomic(1)
cDNA(14)
Primer pair(11)
Other(4)
Antibodies(9)
Microarray probesets(3)
|
Other database
links
|
|
Protein
domains
|
Graphical View
of Protein Domain Structure
|
|
References
|
(Earliest)
J:15273
Ohlsson H et al.,
"IPF1, a homeodomain-containing transactivator of the insulin gene."
EMBO J 1993 Nov;12(11):4251-9
(Latest)
J:155929
Soyer J et al.,
"Rfx6 is an Ngn3-dependent winged helix transcription factor required for pancreatic islet cell development."
Development 2010 Jan;137(2):203-12
|
All references(256)
|
Other
accession IDs
|
MGD-MRK-11442, MGD-MRK-23684
|
Analysis Tools
MGI BioMart
