Symbol
Name
ID
|
|
|
Synonyms
|
Acas1, Facl2
|
|
Genetic Map
|
|
Chromosome 8
|
cytoband B2
|
|
|
|
Mapping data(
2)
|
|
|
|
Sequence Map
|
|
Mammalian
homology
|
|
|
Sequences
|
All sequences(28)
|
Alleles
and
phenotypes
|
All alleles(4) :
Targeted, other(1)
Gene trapped(3)
| iver acyl-CoA levels are reduced when this gene is conditionally knocked out in the liver. |
|
|
Polymorphisms
|
SNPs within 2kb(328 from dbSNP Build 128)
|
Gene Ontology
(GO)
classifications
|
|
|
Expression
|
Literature Summary: (4 records)
Data Summary:
Assays (5)
Results (109)
Tissues (97)
Images (16)
Theiler Stages: 21,22,24,28
| |
Assay Type |
Assays |
|
Results |
| |
RT-PCR |
3 |
|
14 |
| |
RNA in situ |
2 |
|
95 |
cDNA source data(184)
External Resources:
Allen Brain Atlas
GEO
ArrayExpress
|
Molecular
reagents
|
All nucleic(187)
cDNA(184)
Primer pair(3)
Microarray probesets(5)
|
|
Pathways
|
|
Other database
links
|
|
Protein
domains
|
| InterPro ID |
Description |
| IPR000873 |
AMP-dependent synthetase/ligase |
| IPR020845 |
AMP-binding, conserved site |
Graphical View
of Protein Domain Structure
|
|
References
|
(Earliest)
J:2016
Weiner FR et al.,
"Regulation of gene expression by insulin and tumor necrosis factor alpha in 3T3-L1 cells. Modulation of the transcription of genes encoding acyl-CoA synthetase and stearoyl-CoA desaturase-1."
J Biol Chem 1991 Dec 15;266(35):23525-8
(Latest)
J:155714
Li LO et al.,
"Liver-specific loss of long chain acyl-CoA synthetase-1 decreases triacylglycerol synthesis and beta-oxidation and alters phospholipid fatty acid composition."
J Biol Chem 2009 Oct 9;284(41):27816-26
|
All references(13)
|
Other
accession IDs
|
MGD-MRK-1026, MGD-MRK-19705, MGI:87869
|
Analysis Tools
MGI BioMart