Symbol
Name
ID
|
|
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Synonyms
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B7-1, B7.1, Cd28l, Ly-53, Ly53
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Genetic Map
|
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Sequence Map
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Mammalian
homology
|
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Sequences
|
All sequences(42)
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Alleles
and
phenotypes
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All alleles(20) :
Targeted, knock-out(2)
Gene trapped(18)
| Homozygous mutation of this gene results in a 70% reduction in the mixed lymphocyte response in LPS- and dextran sulfate-stimulated B cells. |
Associated Human Diseases (1)
Alleles Annotated to Human Diseases (1)
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Polymorphisms
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RFLP(2)
SNPs within 2kb(142 from dbSNP Build 128)
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Gene Ontology
(GO)
classifications
|
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Expression
|
Literature Summary: (1 records)
Data Summary:
Assays (1)
Results (1)
Tissues (1)
Theiler Stages: 26
| |
Assay Type |
Assays |
|
Results |
| |
Immunohistochemistry |
1 |
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1 |
cDNA source data(17)
External Resources:
Allen Brain Atlas
GEO
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Molecular
reagents
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All nucleic(30)
Genomic(12)
cDNA(18)
Antibodies(1)
Microarray probesets(4)
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Other database
links
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Protein
domains
|
Graphical View
of Protein Domain Structure
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References
|
(Earliest)
J:10835
Kubota H et al.,
"Identification and gene cloning of a new phosphatidylinositol-linked antigen expressed on mature lymphocytes. Down-regulation by lymphocyte activation."
J Immunol 1990 Dec 1;145(11):3924-31
(Latest)
J:154179
Ruffner MA et al.,
"B7-1/2, but not PD-L1/2 molecules, are required on IL-10-treated tolerogenic DC and DC-derived exosomes for in vivo function."
Eur J Immunol 2009 Sep 15;39(11):3084-3090
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All references(172)
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Other
accession IDs
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MGD-MRK-11996, MGD-MRK-12039, MGD-MRK-1846, MGD-MRK-18582
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