Tg(APP695)3Dbo Other Genome Feature Detail
Symbol
Name
ID
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Synonyms
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APP695, APP695swe, APPswe, line C3-3, Mo/HuAPPswe
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Genetic Map
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Alleles
and
phenotypes
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All alleles(1) :
Transgenic(1)
| Aged mice show dramatically increased levels of amyloid peptide levels concurrent with first formation of amyloid deposits, but show no signs of cognitive impairment. |
Associated Human Diseases (3)
Alleles Annotated to Human Diseases (1)
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References
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(Earliest)
J:12201
Simpson RJ,
"Effect of hypoxic exposure on iron absorption in heterozygous hypotransferrinaemic mice."
Ann Hematol 1992 Dec;65(6):260-4
(Latest)
J:152965
Li L et al.,
"Hypoxia increases Abeta generation by altering beta- and gamma-cleavage of APP."
Neurobiol Aging 2009 Jul;30(7):1091-8
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All references(51)
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