MGI 5.13 - Phenotype Browser

Mammalian Phenotype Browser
Term Detail

MP term:	mesangiolysis
Synonym:	dissolution of the mesangial matrix
Synonym:	mesangial cell degeneration
MP id:	MP:0011430
Definition:	an injurious glomerular process that affects primarily the mesangium, starting with loosening and detachment of its matrix and progressing to dissolution/attenuation with degeneration of mesangial cells; mesangial cells may show only edema and vacuolization, or may undergo severe degeneration and necrosis
Number of paths to term:	2

denotes an 'is-a' relationship
denotes a 'part-of' relationship

mammalian phenotype

renal/urinary system phenotype

abnormal renal/urinary system morphology

abnormal kidney morphology

abnormal kidney cortex morphology

abnormal renal corpuscle morphology

abnormal renal glomerulus morphology

abnormal glomerular mesangium morphology

abnormal mesangial cell morphology +

abnormal mesangial matrix morphology +

mesangiolysis [MP:0011430] (16 genotypes, 16 annotations)