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Mammalian Phenotype Browser
Term Detail
MP term:renal tubule atrophy
Synonym: atrophic renal tubules
MP id: MP:0011346
Definition: acquired diminution of the size of the loops of Henle, the proximal convoluted tubule or the distal convoluted tubule associated with wasting as from death and reabsorbtion of cells, diminished cellular proliferation, decreased cellular volume, pressure, ischemia, malnutrition, reduced function or malfunction, or hormonal changes
Number of paths to term: 2

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-arenal/urinary system phenotype
                is-aabnormal renal/urinary system morphology
                        is-aabnormal kidney morphology
                                is-aabnormal kidney size
                                        is-asmall kidney
                                                is-akidney atrophy
                                                        is-akidney cortex atrophy
                                                        is-akidney medulla atrophy
                                                        is-arenal glomerulus atrophy
                                                        is-arenal tubule atrophy [MP:0011346] (42 genotypes, 42 annotations)


mammalian phenotype
        is-arenal/urinary system phenotype
                is-aabnormal renal/urinary system morphology
                        is-aabnormal kidney morphology
                                is-aabnormal nephron morphology
                                        is-aabnormal renal tubule morphology
                                                is-aabnormal distal convoluted tubule morphology +
                                                is-aabnormal loop of Henle morphology +
                                                is-aabnormal proximal convoluted tubule morphology +
                                                is-aabnormal renal tubule epithelium morphology +
                                                is-aaccumulation of giant lysosomes in kidney/renal tubule cells
                                                is-adecreased renal tubule number
                                                is-adilated renal tubules +
                                                is-arenal tubular necrosis
                                                is-arenal tubule atrophy [MP:0011346] (42 genotypes, 42 annotations)
                                                is-arenal tubule hypertrophy
                                                is-atubular nephritis

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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory