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Mammalian Phenotype Browser
Term Detail
MP term:abnormal circulating complement protein level
Synonym: abnormal circulating complement component level
MP id: MP:0010215
Definition: deviation from the normal levels of the serum proteins that act sequentially to allow for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes
Number of paths to term: 5

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-ahomeostasis/metabolism phenotype
                is-aabnormal homeostasis
                        is-aabnormal blood homeostasis
                                is-aabnormal circulating protein level
                                        is-aabnormal circulating angiotensinogen level +
                                        is-aabnormal circulating antithrombin level +
                                        is-aabnormal circulating apolipoprotein level +
                                        is-aabnormal circulating C-reactive protein level
                                        is-aabnormal circulating complement protein level [MP:0010215] (6 genotypes, 6 annotations)
                                                is-adecreased circulating complement protein level
                                                is-aincreased circulating complement protein level
                                        is-aabnormal circulating cytokine level +
                                        is-aabnormal circulating enzyme level +
                                        is-aabnormal circulating factor VIII level +
                                        is-aabnormal circulating ferritin level +
                                        is-aabnormal circulating fibrinogen level +
                                        is-aabnormal circulating fibronectin level +
                                        is-aabnormal circulating prothrombin level +
                                        is-aabnormal circulating retinol binding protein level
                                        is-aabnormal circulating serum albumin level +
                                        is-aabnormal circulating serum amyloid protein level
                                        is-aabnormal circulating thrombin level +
                                        is-aabnormal circulating total protein level +
                                        is-aabnormal circulating transferrin level +
                                        is-aabnormal glycosylated hemoglobin level +
                                        is-adecreased circulating ceruloplasmin level
                                        is-adecreased circulating haptoglobin level
                                        is-ahemoglobinemia
                                        is-aincreased circulating ceruloplasmin level
                                        is-aincreased circulating haptoglobin level


mammalian phenotype
        is-ahomeostasis/metabolism phenotype
                is-aabnormal homeostasis
                        is-aabnormal protein level
                                is-aabnormal circulating protein level
                                        is-aabnormal circulating angiotensinogen level +
                                        is-aabnormal circulating antithrombin level +
                                        is-aabnormal circulating apolipoprotein level +
                                        is-aabnormal circulating C-reactive protein level
                                        is-aabnormal circulating complement protein level [MP:0010215] (6 genotypes, 6 annotations)
                                                is-adecreased circulating complement protein level
                                                is-aincreased circulating complement protein level
                                        is-aabnormal circulating cytokine level +
                                        is-aabnormal circulating enzyme level +
                                        is-aabnormal circulating factor VIII level +
                                        is-aabnormal circulating ferritin level +
                                        is-aabnormal circulating fibrinogen level +
                                        is-aabnormal circulating fibronectin level +
                                        is-aabnormal circulating prothrombin level +
                                        is-aabnormal circulating retinol binding protein level
                                        is-aabnormal circulating serum albumin level +
                                        is-aabnormal circulating serum amyloid protein level
                                        is-aabnormal circulating thrombin level +
                                        is-aabnormal circulating total protein level +
                                        is-aabnormal circulating transferrin level +
                                        is-aabnormal glycosylated hemoglobin level +
                                        is-adecreased circulating ceruloplasmin level
                                        is-adecreased circulating haptoglobin level
                                        is-ahemoglobinemia
                                        is-aincreased circulating ceruloplasmin level
                                        is-aincreased circulating haptoglobin level


mammalian phenotype
        is-ahomeostasis/metabolism phenotype
                is-aabnormal homeostasis
                        is-aabnormal protein level
                                is-aabnormal complement protein level
                                        is-aabnormal circulating complement protein level [MP:0010215] (6 genotypes, 6 annotations)
                                                is-adecreased circulating complement protein level
                                                is-aincreased circulating complement protein level
                                        is-aabnormal complement C5 level +


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system physiology
                        is-aabnormal humoral immune response
                                is-aabnormal complement pathway
                                        is-aabnormal complement protein level
                                                is-aabnormal circulating complement protein level [MP:0010215] (6 genotypes, 6 annotations)
                                                        is-adecreased circulating complement protein level
                                                        is-aincreased circulating complement protein level
                                                is-aabnormal complement C5 level +


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system physiology
                        is-aabnormal innate immunity
                                is-aabnormal complement pathway
                                        is-aabnormal complement protein level
                                                is-aabnormal circulating complement protein level [MP:0010215] (6 genotypes, 6 annotations)
                                                        is-adecreased circulating complement protein level
                                                        is-aincreased circulating complement protein level
                                                is-aabnormal complement C5 level +

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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory