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Mammalian Phenotype Browser
Term Detail
MP term:abnormal gastroesophageal sphincter physiology
Synonym: abnormal cardiac sphincter physiology
Synonym: abnormal constrictor cardiae physiology
Synonym: abnormal esophageal sphincter physiology
Synonym: abnormal inferior esophageal sphincter physiology
Synonym: abnormal lower esophageal sphincter physiology
MP id: MP:0010154
Definition: any functional anomaly of the thick circular layer of gastric musculature encircling the gastroesophageal junction that functions to reduce backflow into the esophagus from the stomach
Number of paths to term: 2

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-adigestive/alimentary phenotype
                is-aabnormal digestive system physiology
                        is-aabnormal defecation +
                        is-aabnormal digestion +
                        is-aabnormal exocrine pancreas physiology +
                        is-aabnormal feces composition +
                        is-aabnormal gastroesophageal sphincter physiology [MP:0010154] (1 genotype, 1 annotation)
                                is-aesophageal achalasia
                                is-agastroesophageal reflux
                        is-aabnormal gastrointestinal motility +
                        is-aabnormal gut flora balance
                        is-aabnormal intestine physiology +
                        is-aabnormal salivary gland physiology +
                        is-aabnormal stomach pH +
                        is-adysphagia
                        is-aesophageal inflammation
                        is-agastrointestinal hemorrhage +
                        is-ameteorism
                        is-apalate inflammation
                        is-aperitoneal inflammation
                        is-astomach inflammation
                        is-astomatitis


mammalian phenotype
        is-amuscle phenotype
                is-aabnormal muscle physiology
                        is-aabnormal cardiomyocyte apoptosis +
                        is-aabnormal fetal cardiomyocyte proliferation +
                        is-aabnormal gastroesophageal sphincter physiology [MP:0010154] (1 genotype, 1 annotation)
                                is-aesophageal achalasia
                                is-agastroesophageal reflux
                        is-aabnormal muscle cell glucose uptake +
                        is-aabnormal muscle contractility +
                        is-aabnormal muscle electrophysiology
                        is-aabnormal muscle precursor cell physiology +
                        is-aabnormal muscle regeneration +
                        is-aabnormal muscle relaxation +
                        is-aabnormal muscle tone +
                        is-aabnormal skeletal muscle cell apoptosis +
                        is-aabnormal skeletal muscle satellite cell proliferation
                        is-aabnormal tendon stiffness +
                        is-aabnormal vascular smooth muscle physiology +
                        is-acardiomyopathy +
                        is-adecreased skeletal muscle glycogen level
                        is-aincreased muscle free fatty acid level
                        is-aincreased skeletal muscle glycogen level
                        is-amuscle fatigue
                        is-amuscle twitch +
                        is-amuscle weakness +
                        is-amyopathy
                        is-amyositis
                        is-aophthalmoplegia

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory