| MP term: | abnormal pancreatic beta cell differentiation |
| Synonym: | abnormal insulin-secreting cell differentiation |
| Synonym: | abnormal pancreatic B cell differentiation |
| MP id: | MP:0009175 |
| Definition: | atypical production of or inability to produce the cells that secrete insulin and are located towards the center of the islets of Langerhans in the pancreas, and/or accumulation of pancreatic beta cell precursors |
| Number of paths to term: | 3 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
cellular phenotypeabnormal cell physiologyabnormal cell differentiationabnormal airway basal cell differentiationabnormal Bergmann glial cell differentiationabnormal dendritic cell differentiation +abnormal enterocyte differentiationabnormal fat cell differentiation +abnormal granulocyte differentiation +abnormal keratinocyte differentiation +abnormal megakaryocyte differentiationabnormal mesenchymal cell differentiation involved in lung developmentabnormal mononuclear cell differentiation +abnormal myoblast differentiationabnormal neuron differentiation +abnormal organ of Corti supporting cell differentiation +abnormal osteoblast differentiation +abnormal osteoclast differentiationabnormal pancreatic alpha cell differentiationabnormal pancreatic beta cell differentiation [MP:0009175] (15 genotypes, 15 annotations)abnormal pancreatic delta cell differentiationabnormal pancreatic epsilon cell differentiationabnormal PP cell differentiationabnormal vascular endothelial cell differentiationimpaired granulosa cell differentiation +impaired luteal cell differentiationendocrine/exocrine gland phenotypeabnormal gland morphologyabnormal pancreas morphologyabnormal endocrine pancreas morphologyabnormal pancreatic islet morphologyabnormal pancreatic beta cell morphologyabnormal pancreatic beta cell differentiation [MP:0009175] (15 genotypes, 15 annotations)abnormal pancreatic beta cell mass +decreased pancreatic beta cell number +degranulated pancreatic beta cellsincreased pancreatic beta cell numberendocrine/exocrine gland phenotypeabnormal gland morphologyabnormal pancreas morphologyabnormal pancreas developmentabnormal endocrine pancreas developmentabnormal pancreatic alpha cell differentiationabnormal pancreatic beta cell differentiation [MP:0009175] (15 genotypes, 15 annotations)abnormal pancreatic delta cell differentiationabnormal pancreatic epsilon cell differentiationabnormal PP cell differentiationMouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 06/12/2013 MGI 5.14 |
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