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Mammalian Phenotype Browser
Term Detail
MP term:abnormal pancreatic beta cell differentiation
Synonym: abnormal insulin-secreting cell differentiation
Synonym: abnormal pancreatic B cell differentiation
MP id: MP:0009175
Definition: atypical production of or inability to produce the cells that secrete insulin and are located towards the center of the islets of Langerhans in the pancreas, and/or accumulation of pancreatic beta cell precursors
Number of paths to term: 3

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-acellular phenotype
                is-aabnormal cell physiology
                        is-aabnormal cell differentiation
                                is-aabnormal airway basal cell differentiation
                                is-aabnormal Bergmann glial cell differentiation
                                is-aabnormal dendritic cell differentiation +
                                is-aabnormal enterocyte differentiation
                                is-aabnormal fat cell differentiation +
                                is-aabnormal granulocyte differentiation +
                                is-aabnormal keratinocyte differentiation +
                                is-aabnormal megakaryocyte differentiation
                                is-aabnormal mesenchymal cell differentiation involved in lung development
                                is-aabnormal mononuclear cell differentiation +
                                is-aabnormal myoblast differentiation
                                is-aabnormal myofibroblast differentiation +
                                is-aabnormal neuron differentiation +
                                is-aabnormal organ of Corti supporting cell differentiation +
                                is-aabnormal osteoblast differentiation +
                                is-aabnormal osteoclast differentiation
                                is-aabnormal pancreatic alpha cell differentiation
                                is-aabnormal pancreatic beta cell differentiation [MP:0009175] (18 genotypes, 18 annotations)
                                is-aabnormal pancreatic delta cell differentiation
                                is-aabnormal pancreatic epsilon cell differentiation
                                is-aabnormal PP cell differentiation
                                is-aabnormal vascular endothelial cell differentiation
                                is-aimpaired granulosa cell differentiation +
                                is-aimpaired luteal cell differentiation
                                is-aimpaired neural crest cell differentiation +


mammalian phenotype
        is-aendocrine/exocrine gland phenotype
                is-aabnormal gland morphology
                        is-aabnormal pancreas morphology
                                is-aabnormal endocrine pancreas morphology
                                        is-aabnormal pancreatic islet morphology
                                                is-aabnormal pancreatic beta cell morphology
                                                        is-aabnormal pancreatic beta cell differentiation [MP:0009175] (18 genotypes, 18 annotations)
                                                        is-aabnormal pancreatic beta cell mass +
                                                        is-adecreased pancreatic beta cell number +
                                                        is-adegranulated pancreatic beta cells
                                                        is-aincreased pancreatic beta cell number


mammalian phenotype
        is-aendocrine/exocrine gland phenotype
                is-aabnormal gland morphology
                        is-aabnormal pancreas morphology
                                is-aabnormal pancreas development
                                        is-aabnormal endocrine pancreas development
                                                is-aabnormal pancreatic alpha cell differentiation
                                                is-aabnormal pancreatic beta cell differentiation [MP:0009175] (18 genotypes, 18 annotations)
                                                is-aabnormal pancreatic delta cell differentiation
                                                is-aabnormal pancreatic epsilon cell differentiation
                                                is-aabnormal PP cell differentiation

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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory