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Mammalian Phenotype Browser
Term Detail
MP term:decreased interleukin-21 secretion
Synonym: decreased IL-21 secretion
Synonym: decreased IL21 secretion
Synonym: reduced IL-21 secretion
Synonym: reduced IL21 secretion
Synonym: reduced interleukin-21 secretion
MP id: MP:0009058
Definition: reduction in the production or release of a pleiotropic cytokine that regulates immunoglobulin production, plasma cell and Th17 T cell differentiation, CD8+ T cell expansion, and inhibits antigen presentation by dendritic cells
Number of paths to term: 1

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship

mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system physiology
                        is-aabnormal immune serum protein physiology
                                is-aabnormal cytokine secretion
                                        is-aabnormal interleukin secretion
                                                is-aabnormal interleukin-21 secretion
                                                        is-adecreased interleukin-21 secretion [MP:0009058] (7 genotypes, 7 annotations)
                                                        is-aincreased interleukin-21 secretion

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.08
The Jackson Laboratory