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Mammalian Phenotype Browser
Term Detail
MP term:abnormal interferon level
MP id: MP:0008750
Definition: deviation from the normal levels of proteins secreted by vertebrate cells in response to a wide variety of inducers; they confer resistance against many different viruses, inhibit proliferation of normal and malignant cells, impede multiplication of intracellular parasites, enhance macrophage and granulocyte phagocytosis, augment natural killer cell activity, and show several other immunomodulatory functions
Number of paths to term: 2

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-ahomeostasis/metabolism phenotype
                is-aabnormal homeostasis
                        is-aabnormal protein level
                                is-aabnormal intercellular signaling peptide or protein level
                                        is-aabnormal cytokine level
                                                is-aabnormal chemokine level +
                                                is-aabnormal circulating cytokine level +
                                                is-aabnormal interferon level [MP:0008750] (151 genotypes, 169 annotations)
                                                        is-aabnormal circulating interferon level +
                                                is-aabnormal interleukin level +
                                                is-aabnormal tumor necrosis factor level +


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system physiology
                        is-aabnormal immune serum protein physiology
                                is-aabnormal cytokine level
                                        is-aabnormal chemokine level +
                                        is-aabnormal circulating cytokine level +
                                        is-aabnormal interferon level [MP:0008750] (151 genotypes, 169 annotations)
                                                is-aabnormal circulating interferon level +
                                        is-aabnormal interleukin level +
                                        is-aabnormal tumor necrosis factor level +

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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory