| MP term: | increased circulating interleukin-12 level |
| Synonym: | increased circulating cytotoxic lymphocyte maturation factor level |
| Synonym: | increased circulating IL-12 level |
| Synonym: | increased circulating IL12 level |
| Synonym: | increased circulating IL-12 p70 level |
| Synonym: | increased circulating interleukin-12 p70 level |
| Synonym: | increased circulating natural killer cell stimulatory factor level |
| MP id: | MP:0008617 |
| Definition: | increase in the amount in the blood of a heterodimeric cytokine that plays a role in innate and adaptive immune responses; it is produced by dendritic cells, macrophages and a variety of other immune cells and plays a role in the stimulation of interferon-gamma production by T-cells and natural killer cells |
| Number of paths to term: | 6 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
homeostasis/metabolism phenotypeabnormal homeostasisabnormal blood homeostasisabnormal circulating protein levelabnormal circulating cytokine levelabnormal circulating interleukin levelabnormal circulating interleukin-12 levelabnormal circulating interleukin-12a level +decreased circulating interleukin-12 levelincreased circulating interleukin-12 level [MP:0008617] (23 genotypes, 23 annotations)homeostasis/metabolism phenotypeabnormal homeostasisabnormal protein levelabnormal circulating protein levelabnormal circulating cytokine levelabnormal circulating interleukin levelabnormal circulating interleukin-12 levelabnormal circulating interleukin-12a level +decreased circulating interleukin-12 levelincreased circulating interleukin-12 level [MP:0008617] (23 genotypes, 23 annotations)homeostasis/metabolism phenotypeabnormal homeostasisabnormal protein levelabnormal intercellular signaling peptide or protein levelabnormal cytokine levelabnormal circulating cytokine levelabnormal circulating interleukin levelabnormal circulating interleukin-12 levelabnormal circulating interleukin-12a level +decreased circulating interleukin-12 levelincreased circulating interleukin-12 level [MP:0008617] (23 genotypes, 23 annotations)homeostasis/metabolism phenotypeabnormal homeostasisabnormal protein levelabnormal intercellular signaling peptide or protein levelabnormal cytokine levelabnormal interleukin levelabnormal circulating interleukin levelabnormal circulating interleukin-12 levelabnormal circulating interleukin-12a level +decreased circulating interleukin-12 levelincreased circulating interleukin-12 level [MP:0008617] (23 genotypes, 23 annotations)immune system phenotypeabnormal immune system physiologyabnormal immune serum protein physiologyabnormal cytokine levelabnormal circulating cytokine levelabnormal circulating interleukin levelabnormal circulating interleukin-12 levelabnormal circulating interleukin-12a level +decreased circulating interleukin-12 levelincreased circulating interleukin-12 level [MP:0008617] (23 genotypes, 23 annotations)immune system phenotypeabnormal immune system physiologyabnormal immune serum protein physiologyabnormal cytokine levelabnormal interleukin levelabnormal circulating interleukin levelabnormal circulating interleukin-12 levelabnormal circulating interleukin-12a level +decreased circulating interleukin-12 levelincreased circulating interleukin-12 level [MP:0008617] (23 genotypes, 23 annotations)Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/08/2013 MGI 5.13 |
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