About   Help   FAQ
Mammalian Phenotype Browser
Term Detail
MP term:increased circulating interleukin-12 level
Synonym: increased circulating cytotoxic lymphocyte maturation factor level
Synonym: increased circulating IL-12 level
Synonym: increased circulating IL12 level
Synonym: increased circulating IL-12 p70 level
Synonym: increased circulating interleukin-12 p70 level
Synonym: increased circulating natural killer cell stimulatory factor level
MP id: MP:0008617
Definition: increase in the amount in the blood of a heterodimeric cytokine that plays a role in innate and adaptive immune responses; it is produced by dendritic cells, macrophages and a variety of other immune cells and plays a role in the stimulation of interferon-gamma production by T-cells and natural killer cells
Number of paths to term: 6

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-ahomeostasis/metabolism phenotype
                is-aabnormal homeostasis
                        is-aabnormal blood homeostasis
                                is-aabnormal circulating protein level
                                        is-aabnormal circulating cytokine level
                                                is-aabnormal circulating interleukin level
                                                        is-aabnormal circulating interleukin-12 level
                                                                is-aabnormal circulating interleukin-12a level +
                                                                is-adecreased circulating interleukin-12 level
                                                                is-aincreased circulating interleukin-12 level [MP:0008617] (26 genotypes, 26 annotations)


mammalian phenotype
        is-ahomeostasis/metabolism phenotype
                is-aabnormal homeostasis
                        is-aabnormal protein level
                                is-aabnormal circulating protein level
                                        is-aabnormal circulating cytokine level
                                                is-aabnormal circulating interleukin level
                                                        is-aabnormal circulating interleukin-12 level
                                                                is-aabnormal circulating interleukin-12a level +
                                                                is-adecreased circulating interleukin-12 level
                                                                is-aincreased circulating interleukin-12 level [MP:0008617] (26 genotypes, 26 annotations)


mammalian phenotype
        is-ahomeostasis/metabolism phenotype
                is-aabnormal homeostasis
                        is-aabnormal protein level
                                is-aabnormal intercellular signaling peptide or protein level
                                        is-aabnormal cytokine level
                                                is-aabnormal circulating cytokine level
                                                        is-aabnormal circulating interleukin level
                                                                is-aabnormal circulating interleukin-12 level
                                                                        is-aabnormal circulating interleukin-12a level +
                                                                        is-adecreased circulating interleukin-12 level
                                                                        is-aincreased circulating interleukin-12 level [MP:0008617] (26 genotypes, 26 annotations)


mammalian phenotype
        is-ahomeostasis/metabolism phenotype
                is-aabnormal homeostasis
                        is-aabnormal protein level
                                is-aabnormal intercellular signaling peptide or protein level
                                        is-aabnormal cytokine level
                                                is-aabnormal interleukin level
                                                        is-aabnormal circulating interleukin level
                                                                is-aabnormal circulating interleukin-12 level
                                                                        is-aabnormal circulating interleukin-12a level +
                                                                        is-adecreased circulating interleukin-12 level
                                                                        is-aincreased circulating interleukin-12 level [MP:0008617] (26 genotypes, 26 annotations)


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system physiology
                        is-aabnormal immune serum protein physiology
                                is-aabnormal cytokine level
                                        is-aabnormal circulating cytokine level
                                                is-aabnormal circulating interleukin level
                                                        is-aabnormal circulating interleukin-12 level
                                                                is-aabnormal circulating interleukin-12a level +
                                                                is-adecreased circulating interleukin-12 level
                                                                is-aincreased circulating interleukin-12 level [MP:0008617] (26 genotypes, 26 annotations)


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system physiology
                        is-aabnormal immune serum protein physiology
                                is-aabnormal cytokine level
                                        is-aabnormal interleukin level
                                                is-aabnormal circulating interleukin level
                                                        is-aabnormal circulating interleukin-12 level
                                                                is-aabnormal circulating interleukin-12a level +
                                                                is-adecreased circulating interleukin-12 level
                                                                is-aincreased circulating interleukin-12 level [MP:0008617] (26 genotypes, 26 annotations)

Back to entry page

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
12/09/2014
MGI 5.20
The Jackson Laboratory