| MP term: | abnormal spleen marginal zone macrophage morphology |
| Synonym: | abnormal ER-TR9 positive cells |
| Synonym: | abnormal splenic marginal zone macrophage morphology |
| MP id: | MP:0008240 |
| Definition: | any structural anomaly of the cells present in the splenic marginal zone and are involved in the recognition and clearance of material, such as pathogen-derived material, from the splenic circulation |
| Number of paths to term: | 9 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
hematopoietic system phenotypeabnormal hematopoietic system morphology/developmentabnormal blood cell morphology/developmentabnormal hematopoiesisabnormal leukocyte morphologyabnormal mononuclear cell morphologyabnormal mononuclear phagocyte morphologyabnormal macrophage morphologyabnormal alveolar macrophage morphologyabnormal Kupffer cell morphologyabnormal macrophage derived foam cell morphology +abnormal macrophage differentiationabnormal metallophilic macrophage morphologyabnormal microglial cell morphology +abnormal osteoclast morphology +abnormal peritoneal macrophage morphologyabnormal perivascular macrophage morphologyabnormal spleen marginal zone macrophage morphology [MP:0008240] (9 genotypes, 9 annotations)decreased macrophage cell number +increased macrophage cell number +hematopoietic system phenotypeabnormal hematopoietic system morphology/developmentabnormal blood cell morphology/developmentabnormal hematopoiesisabnormal leukocyte morphologyabnormal myeloid leukocyte morphologyabnormal phagocyte morphologyabnormal mononuclear phagocyte morphologyabnormal macrophage morphologyabnormal alveolar macrophage morphologyabnormal Kupffer cell morphologyabnormal macrophage derived foam cell morphology +abnormal macrophage differentiationabnormal metallophilic macrophage morphologyabnormal microglial cell morphology +abnormal osteoclast morphology +abnormal peritoneal macrophage morphologyabnormal perivascular macrophage morphologyabnormal spleen marginal zone macrophage morphology [MP:0008240] (9 genotypes, 9 annotations)decreased macrophage cell number +increased macrophage cell number +hematopoietic system phenotypeabnormal hematopoietic system morphology/developmentabnormal blood cell morphology/developmentabnormal leukocyte morphologyabnormal mononuclear cell morphologyabnormal mononuclear phagocyte morphologyabnormal macrophage morphologyabnormal alveolar macrophage morphologyabnormal Kupffer cell morphologyabnormal macrophage derived foam cell morphology +abnormal macrophage differentiationabnormal metallophilic macrophage morphologyabnormal microglial cell morphology +abnormal osteoclast morphology +abnormal peritoneal macrophage morphologyabnormal perivascular macrophage morphologyabnormal spleen marginal zone macrophage morphology [MP:0008240] (9 genotypes, 9 annotations)decreased macrophage cell number +increased macrophage cell number +hematopoietic system phenotypeabnormal hematopoietic system morphology/developmentabnormal blood cell morphology/developmentabnormal leukocyte morphologyabnormal myeloid leukocyte morphologyabnormal phagocyte morphologyabnormal mononuclear phagocyte morphologyabnormal macrophage morphologyabnormal alveolar macrophage morphologyabnormal Kupffer cell morphologyabnormal macrophage derived foam cell morphology +abnormal macrophage differentiationabnormal metallophilic macrophage morphologyabnormal microglial cell morphology +abnormal osteoclast morphology +abnormal peritoneal macrophage morphologyabnormal perivascular macrophage morphologyabnormal spleen marginal zone macrophage morphology [MP:0008240] (9 genotypes, 9 annotations)decreased macrophage cell number +increased macrophage cell number +hematopoietic system phenotypeabnormal hematopoietic system morphology/developmentabnormal spleen morphologyabnormal spleen white pulp morphologyabnormal spleen marginal zone morphologyabnormal marginal zone B cell morphology +abnormal spleen marginal zone macrophage morphology [MP:0008240] (9 genotypes, 9 annotations)absent spleen marginal zoneimmune system phenotypeabnormal immune system morphologyabnormal immune system cell morphologyabnormal leukocyte morphologyabnormal mononuclear cell morphologyabnormal mononuclear phagocyte morphologyabnormal macrophage morphologyabnormal alveolar macrophage morphologyabnormal Kupffer cell morphologyabnormal macrophage derived foam cell morphology +abnormal macrophage differentiationabnormal metallophilic macrophage morphologyabnormal microglial cell morphology +abnormal osteoclast morphology +abnormal peritoneal macrophage morphologyabnormal perivascular macrophage morphologyabnormal spleen marginal zone macrophage morphology [MP:0008240] (9 genotypes, 9 annotations)decreased macrophage cell number +increased macrophage cell number +immune system phenotypeabnormal immune system morphologyabnormal immune system cell morphologyabnormal leukocyte morphologyabnormal myeloid leukocyte morphologyabnormal phagocyte morphologyabnormal mononuclear phagocyte morphologyabnormal macrophage morphologyabnormal alveolar macrophage morphologyabnormal Kupffer cell morphologyabnormal macrophage derived foam cell morphology +abnormal macrophage differentiationabnormal metallophilic macrophage morphologyabnormal microglial cell morphology +abnormal osteoclast morphology +abnormal peritoneal macrophage morphologyabnormal perivascular macrophage morphologyabnormal spleen marginal zone macrophage morphology [MP:0008240] (9 genotypes, 9 annotations)decreased macrophage cell number +increased macrophage cell number +immune system phenotypeabnormal immune system morphologyabnormal immune system cell morphologyabnormal professional antigen presenting cell morphologyabnormal macrophage morphologyabnormal alveolar macrophage morphologyabnormal Kupffer cell morphologyabnormal macrophage derived foam cell morphology +abnormal macrophage differentiationabnormal metallophilic macrophage morphologyabnormal microglial cell morphology +abnormal osteoclast morphology +abnormal peritoneal macrophage morphologyabnormal perivascular macrophage morphologyabnormal spleen marginal zone macrophage morphology [MP:0008240] (9 genotypes, 9 annotations)decreased macrophage cell number +increased macrophage cell number +immune system phenotypeabnormal immune system morphologyabnormal immune system organ morphologyabnormal spleen morphologyabnormal spleen white pulp morphologyabnormal spleen marginal zone morphologyabnormal marginal zone B cell morphology +abnormal spleen marginal zone macrophage morphology [MP:0008240] (9 genotypes, 9 annotations)absent spleen marginal zoneMouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/08/2013 MGI 5.13 |
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