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Term Detail
MP term:decreased susceptibility to neuronal excitotoxicity
Synonym: decreased susceptibility to neurotoxicity-induced cell death
Synonym: increased resistance to neuronal excitotoxicity
Synonym: reduced susceptibility to neuronal excitotoxicity
MP id: MP:0008236
Definition: less than normal amount of neuronal cell death following exposure to a neurotoxic compound, such as kainate-induced neuronal cell death mediated via a glutamate excitotoxic process
Number of paths to term: 5

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-acellular phenotype
                is-aabnormal cell physiology
                        is-aabnormal cell death
                                is-aabnormal apoptosis
                                        is-aabnormal neuron apoptosis
                                                is-adecreased neuron apoptosis
                                                        is-adecreased susceptibility to neuronal excitotoxicity [MP:0008236] (50 genotypes, 50 annotations)
                                                                is-adecreased susceptibility to dopaminergic neuron neurotoxicity


mammalian phenotype
        is-acellular phenotype
                is-aabnormal cell physiology
                        is-aabnormal cell death
                                is-aabnormal apoptosis
                                        is-adecreased apoptosis
                                                is-adecreased neuron apoptosis
                                                        is-adecreased susceptibility to neuronal excitotoxicity [MP:0008236] (50 genotypes, 50 annotations)
                                                                is-adecreased susceptibility to dopaminergic neuron neurotoxicity


mammalian phenotype
        is-acellular phenotype
                is-aabnormal cell physiology
                        is-aabnormal cell death
                                is-adecreased cell death
                                        is-adecreased apoptosis
                                                is-adecreased neuron apoptosis
                                                        is-adecreased susceptibility to neuronal excitotoxicity [MP:0008236] (50 genotypes, 50 annotations)
                                                                is-adecreased susceptibility to dopaminergic neuron neurotoxicity


mammalian phenotype
        is-ahomeostasis/metabolism phenotype
                is-aabnormal physiological response to xenobiotic
                        is-adecreased physiological sensitivity to xenobiotic
                                is-adecreased bronchoconstrictive response
                                is-adecreased incidence of tumors by chemical induction
                                is-adecreased susceptibility to neuronal excitotoxicity [MP:0008236] (50 genotypes, 50 annotations)
                                        is-adecreased susceptibility to dopaminergic neuron neurotoxicity


mammalian phenotype
        is-anervous system phenotype
                is-aabnormal nervous system physiology
                        is-aabnormal neuron physiology
                                is-aabnormal neuron apoptosis
                                        is-adecreased neuron apoptosis
                                                is-adecreased susceptibility to neuronal excitotoxicity [MP:0008236] (50 genotypes, 50 annotations)
                                                        is-adecreased susceptibility to dopaminergic neuron neurotoxicity

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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory