About   Help   FAQ
Mammalian Phenotype Browser
Term Detail
MP term:increased germinal center B cell number
MP id: MP:0008177
Definition: greater number of rapidly cycling mature B cells which have downregulated IgD expression and exhibit high levels of binding by peanut agglutinin (PNA), and are involved in T-dependent immune responses; germinal center B cells are found typically in the germinal centers of lymph nodes and spleen
Number of paths to term: 22

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal blood cell morphology/development
                                is-aabnormal hematopoiesis
                                        is-aabnormal hematopoietic cell number
                                                is-aabnormal leukocyte cell number
                                                        is-aabnormal lymphocyte cell number
                                                                is-aabnormal B cell number
                                                                        is-aincreased B cell number
                                                                                is-aincreased mature B cell number
                                                                                        is-aincreased B-1 B cell number +
                                                                                        is-aincreased B-2 B cell number
                                                                                        is-aincreased follicular B cell number
                                                                                        is-aincreased germinal center B cell number [MP:0008177] (38 genotypes, 38 annotations)
                                                                                        is-aincreased marginal zone B cell number
                                                                                        is-aincreased memory B cell number
                                                                                        is-aincreased plasma cell number


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal blood cell morphology/development
                                is-aabnormal hematopoiesis
                                        is-aabnormal hematopoietic cell number
                                                is-aabnormal leukocyte cell number
                                                        is-aabnormal lymphocyte cell number
                                                                is-aincreased lymphocyte cell number
                                                                        is-aincreased B cell number
                                                                                is-aincreased mature B cell number
                                                                                        is-aincreased B-1 B cell number +
                                                                                        is-aincreased B-2 B cell number
                                                                                        is-aincreased follicular B cell number
                                                                                        is-aincreased germinal center B cell number [MP:0008177] (38 genotypes, 38 annotations)
                                                                                        is-aincreased marginal zone B cell number
                                                                                        is-aincreased memory B cell number
                                                                                        is-aincreased plasma cell number


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal blood cell morphology/development
                                is-aabnormal hematopoiesis
                                        is-aabnormal hematopoietic cell number
                                                is-aabnormal leukocyte cell number
                                                        is-aincreased leukocyte cell number
                                                                is-aincreased lymphocyte cell number
                                                                        is-aincreased B cell number
                                                                                is-aincreased mature B cell number
                                                                                        is-aincreased B-1 B cell number +
                                                                                        is-aincreased B-2 B cell number
                                                                                        is-aincreased follicular B cell number
                                                                                        is-aincreased germinal center B cell number [MP:0008177] (38 genotypes, 38 annotations)
                                                                                        is-aincreased marginal zone B cell number
                                                                                        is-aincreased memory B cell number
                                                                                        is-aincreased plasma cell number


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal blood cell morphology/development
                                is-aabnormal hematopoiesis
                                        is-aabnormal hematopoietic cell number
                                                is-aincreased hematopoietic cell number
                                                        is-aincreased leukocyte cell number
                                                                is-aincreased lymphocyte cell number
                                                                        is-aincreased B cell number
                                                                                is-aincreased mature B cell number
                                                                                        is-aincreased B-1 B cell number +
                                                                                        is-aincreased B-2 B cell number
                                                                                        is-aincreased follicular B cell number
                                                                                        is-aincreased germinal center B cell number [MP:0008177] (38 genotypes, 38 annotations)
                                                                                        is-aincreased marginal zone B cell number
                                                                                        is-aincreased memory B cell number
                                                                                        is-aincreased plasma cell number


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal blood cell morphology/development
                                is-aabnormal hematopoiesis
                                        is-aabnormal leukocyte morphology
                                                is-aabnormal leukocyte cell number
                                                        is-aabnormal lymphocyte cell number
                                                                is-aabnormal B cell number
                                                                        is-aincreased B cell number
                                                                                is-aincreased mature B cell number
                                                                                        is-aincreased B-1 B cell number +
                                                                                        is-aincreased B-2 B cell number
                                                                                        is-aincreased follicular B cell number
                                                                                        is-aincreased germinal center B cell number [MP:0008177] (38 genotypes, 38 annotations)
                                                                                        is-aincreased marginal zone B cell number
                                                                                        is-aincreased memory B cell number
                                                                                        is-aincreased plasma cell number


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal blood cell morphology/development
                                is-aabnormal hematopoiesis
                                        is-aabnormal leukocyte morphology
                                                is-aabnormal leukocyte cell number
                                                        is-aabnormal lymphocyte cell number
                                                                is-aincreased lymphocyte cell number
                                                                        is-aincreased B cell number
                                                                                is-aincreased mature B cell number
                                                                                        is-aincreased B-1 B cell number +
                                                                                        is-aincreased B-2 B cell number
                                                                                        is-aincreased follicular B cell number
                                                                                        is-aincreased germinal center B cell number [MP:0008177] (38 genotypes, 38 annotations)
                                                                                        is-aincreased marginal zone B cell number
                                                                                        is-aincreased memory B cell number
                                                                                        is-aincreased plasma cell number


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal blood cell morphology/development
                                is-aabnormal hematopoiesis
                                        is-aabnormal leukocyte morphology
                                                is-aabnormal leukocyte cell number
                                                        is-aincreased leukocyte cell number
                                                                is-aincreased lymphocyte cell number
                                                                        is-aincreased B cell number
                                                                                is-aincreased mature B cell number
                                                                                        is-aincreased B-1 B cell number +
                                                                                        is-aincreased B-2 B cell number
                                                                                        is-aincreased follicular B cell number
                                                                                        is-aincreased germinal center B cell number [MP:0008177] (38 genotypes, 38 annotations)
                                                                                        is-aincreased marginal zone B cell number
                                                                                        is-aincreased memory B cell number
                                                                                        is-aincreased plasma cell number


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal blood cell morphology/development
                                is-aabnormal hematopoiesis
                                        is-aabnormal leukocyte morphology
                                                is-aabnormal mononuclear cell morphology
                                                        is-aabnormal lymphocyte morphology
                                                                is-aabnormal B cell morphology
                                                                        is-aabnormal B cell number
                                                                                is-aincreased B cell number
                                                                                        is-aincreased mature B cell number
                                                                                                is-aincreased B-1 B cell number +
                                                                                                is-aincreased B-2 B cell number
                                                                                                is-aincreased follicular B cell number
                                                                                                is-aincreased germinal center B cell number [MP:0008177] (38 genotypes, 38 annotations)
                                                                                                is-aincreased marginal zone B cell number
                                                                                                is-aincreased memory B cell number
                                                                                                is-aincreased plasma cell number


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal blood cell morphology/development
                                is-aabnormal hematopoiesis
                                        is-aabnormal leukocyte morphology
                                                is-aabnormal mononuclear cell morphology
                                                        is-aabnormal lymphocyte morphology
                                                                is-aabnormal B cell morphology
                                                                        is-aabnormal mature B cell morphology
                                                                                is-aabnormal germinal center B cell morphology
                                                                                        is-adecreased germinal center B cell number +
                                                                                        is-aincreased germinal center B cell number [MP:0008177] (38 genotypes, 38 annotations)


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal blood cell morphology/development
                                is-aabnormal hematopoiesis
                                        is-aabnormal leukocyte morphology
                                                is-aabnormal mononuclear cell morphology
                                                        is-aabnormal lymphocyte morphology
                                                                is-aabnormal B cell morphology
                                                                        is-aabnormal mature B cell morphology
                                                                                is-aincreased mature B cell number
                                                                                        is-aincreased B-1 B cell number +
                                                                                        is-aincreased B-2 B cell number
                                                                                        is-aincreased follicular B cell number
                                                                                        is-aincreased germinal center B cell number [MP:0008177] (38 genotypes, 38 annotations)
                                                                                        is-aincreased marginal zone B cell number
                                                                                        is-aincreased memory B cell number
                                                                                        is-aincreased plasma cell number


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal blood cell morphology/development
                                is-aabnormal hematopoiesis
                                        is-aabnormal leukocyte morphology
                                                is-aabnormal mononuclear cell morphology
                                                        is-aabnormal lymphocyte morphology
                                                                is-aabnormal lymphocyte cell number
                                                                        is-aabnormal B cell number
                                                                                is-aincreased B cell number
                                                                                        is-aincreased mature B cell number
                                                                                                is-aincreased B-1 B cell number +
                                                                                                is-aincreased B-2 B cell number
                                                                                                is-aincreased follicular B cell number
                                                                                                is-aincreased germinal center B cell number [MP:0008177] (38 genotypes, 38 annotations)
                                                                                                is-aincreased marginal zone B cell number
                                                                                                is-aincreased memory B cell number
                                                                                                is-aincreased plasma cell number


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal blood cell morphology/development
                                is-aabnormal hematopoiesis
                                        is-aabnormal leukocyte morphology
                                                is-aabnormal mononuclear cell morphology
                                                        is-aabnormal lymphocyte morphology
                                                                is-aabnormal lymphocyte cell number
                                                                        is-aincreased lymphocyte cell number
                                                                                is-aincreased B cell number
                                                                                        is-aincreased mature B cell number
                                                                                                is-aincreased B-1 B cell number +
                                                                                                is-aincreased B-2 B cell number
                                                                                                is-aincreased follicular B cell number
                                                                                                is-aincreased germinal center B cell number [MP:0008177] (38 genotypes, 38 annotations)
                                                                                                is-aincreased marginal zone B cell number
                                                                                                is-aincreased memory B cell number
                                                                                                is-aincreased plasma cell number


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal leukocyte cell number
                                                is-aabnormal lymphocyte cell number
                                                        is-aabnormal B cell number
                                                                is-aincreased B cell number
                                                                        is-aincreased mature B cell number
                                                                                is-aincreased B-1 B cell number +
                                                                                is-aincreased B-2 B cell number
                                                                                is-aincreased follicular B cell number
                                                                                is-aincreased germinal center B cell number [MP:0008177] (38 genotypes, 38 annotations)
                                                                                is-aincreased marginal zone B cell number
                                                                                is-aincreased memory B cell number
                                                                                is-aincreased plasma cell number


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal leukocyte cell number
                                                is-aabnormal lymphocyte cell number
                                                        is-aincreased lymphocyte cell number
                                                                is-aincreased B cell number
                                                                        is-aincreased mature B cell number
                                                                                is-aincreased B-1 B cell number +
                                                                                is-aincreased B-2 B cell number
                                                                                is-aincreased follicular B cell number
                                                                                is-aincreased germinal center B cell number [MP:0008177] (38 genotypes, 38 annotations)
                                                                                is-aincreased marginal zone B cell number
                                                                                is-aincreased memory B cell number
                                                                                is-aincreased plasma cell number


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal leukocyte cell number
                                                is-aincreased leukocyte cell number
                                                        is-aincreased lymphocyte cell number
                                                                is-aincreased B cell number
                                                                        is-aincreased mature B cell number
                                                                                is-aincreased B-1 B cell number +
                                                                                is-aincreased B-2 B cell number
                                                                                is-aincreased follicular B cell number
                                                                                is-aincreased germinal center B cell number [MP:0008177] (38 genotypes, 38 annotations)
                                                                                is-aincreased marginal zone B cell number
                                                                                is-aincreased memory B cell number
                                                                                is-aincreased plasma cell number


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal mononuclear cell morphology
                                                is-aabnormal lymphocyte morphology
                                                        is-aabnormal B cell morphology
                                                                is-aabnormal B cell number
                                                                        is-aincreased B cell number
                                                                                is-aincreased mature B cell number
                                                                                        is-aincreased B-1 B cell number +
                                                                                        is-aincreased B-2 B cell number
                                                                                        is-aincreased follicular B cell number
                                                                                        is-aincreased germinal center B cell number [MP:0008177] (38 genotypes, 38 annotations)
                                                                                        is-aincreased marginal zone B cell number
                                                                                        is-aincreased memory B cell number
                                                                                        is-aincreased plasma cell number


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal mononuclear cell morphology
                                                is-aabnormal lymphocyte morphology
                                                        is-aabnormal B cell morphology
                                                                is-aabnormal mature B cell morphology
                                                                        is-aabnormal germinal center B cell morphology
                                                                                is-adecreased germinal center B cell number +
                                                                                is-aincreased germinal center B cell number [MP:0008177] (38 genotypes, 38 annotations)


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal mononuclear cell morphology
                                                is-aabnormal lymphocyte morphology
                                                        is-aabnormal B cell morphology
                                                                is-aabnormal mature B cell morphology
                                                                        is-aincreased mature B cell number
                                                                                is-aincreased B-1 B cell number +
                                                                                is-aincreased B-2 B cell number
                                                                                is-aincreased follicular B cell number
                                                                                is-aincreased germinal center B cell number [MP:0008177] (38 genotypes, 38 annotations)
                                                                                is-aincreased marginal zone B cell number
                                                                                is-aincreased memory B cell number
                                                                                is-aincreased plasma cell number


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal mononuclear cell morphology
                                                is-aabnormal lymphocyte morphology
                                                        is-aabnormal lymphocyte cell number
                                                                is-aabnormal B cell number
                                                                        is-aincreased B cell number
                                                                                is-aincreased mature B cell number
                                                                                        is-aincreased B-1 B cell number +
                                                                                        is-aincreased B-2 B cell number
                                                                                        is-aincreased follicular B cell number
                                                                                        is-aincreased germinal center B cell number [MP:0008177] (38 genotypes, 38 annotations)
                                                                                        is-aincreased marginal zone B cell number
                                                                                        is-aincreased memory B cell number
                                                                                        is-aincreased plasma cell number


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal mononuclear cell morphology
                                                is-aabnormal lymphocyte morphology
                                                        is-aabnormal lymphocyte cell number
                                                                is-aincreased lymphocyte cell number
                                                                        is-aincreased B cell number
                                                                                is-aincreased mature B cell number
                                                                                        is-aincreased B-1 B cell number +
                                                                                        is-aincreased B-2 B cell number
                                                                                        is-aincreased follicular B cell number
                                                                                        is-aincreased germinal center B cell number [MP:0008177] (38 genotypes, 38 annotations)
                                                                                        is-aincreased marginal zone B cell number
                                                                                        is-aincreased memory B cell number
                                                                                        is-aincreased plasma cell number


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal professional antigen presenting cell morphology
                                        is-aabnormal mature B cell morphology
                                                is-aabnormal germinal center B cell morphology
                                                        is-adecreased germinal center B cell number +
                                                        is-aincreased germinal center B cell number [MP:0008177] (38 genotypes, 38 annotations)


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal professional antigen presenting cell morphology
                                        is-aabnormal mature B cell morphology
                                                is-aincreased mature B cell number
                                                        is-aincreased B-1 B cell number +
                                                        is-aincreased B-2 B cell number
                                                        is-aincreased follicular B cell number
                                                        is-aincreased germinal center B cell number [MP:0008177] (38 genotypes, 38 annotations)
                                                        is-aincreased marginal zone B cell number
                                                        is-aincreased memory B cell number
                                                        is-aincreased plasma cell number

Back to entry page

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/18/2014
MGI 5.20
The Jackson Laboratory