| MP term: | podocyte foot process effacement |
| MP id: | MP:0008140 |
| Definition: | a podocyte reaction to injury or damage characterized by flattening of foot processes due to gradual simplification of the interdigitating foot process; the whole podocyte looks flat due to retraction, widening, and shortening of the processes of each podocyte while the frequency of filtration slits is reduced, giving the appearance of a continuous cytoplasmic sheet covering the glomerular basement membrane |
| Number of paths to term: | 2 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
renal/urinary system phenotypeabnormal renal/urinary system morphologyabnormal kidney morphologyabnormal kidney cortex morphologyabnormal renal corpuscle morphologyabnormal renal glomerular capsule morphologyabnormal glomerular capsule visceral layer morphologyabnormal podocyte morphologyabnormal podocyte foot process morphologyabsent podocyte foot processfused podocyte foot processespodocyte foot process effacement [MP:0008140] (60 genotypes, 60 annotations)renal/urinary system phenotypeabnormal renal/urinary system morphologyabnormal kidney morphologyabnormal nephron morphologyabnormal renal corpuscle morphologyabnormal renal glomerular capsule morphologyabnormal glomerular capsule visceral layer morphologyabnormal podocyte morphologyabnormal podocyte foot process morphologyabsent podocyte foot processfused podocyte foot processespodocyte foot process effacement [MP:0008140] (60 genotypes, 60 annotations)Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/22/2013 MGI 5.13 |
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