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Mammalian Phenotype Browser
Term Detail
MP term:podocyte foot process effacement
MP id: MP:0008140
Definition: a podocyte reaction to injury or damage characterized by flattening of foot processes due to gradual simplification of the interdigitating foot process; the whole podocyte looks flat due to retraction, widening, and shortening of the processes of each podocyte while the frequency of filtration slits is reduced, giving the appearance of a continuous cytoplasmic sheet covering the glomerular basement membrane
Number of paths to term: 2

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-arenal/urinary system phenotype
                is-aabnormal renal/urinary system morphology
                        is-aabnormal kidney morphology
                                is-aabnormal kidney cortex morphology
                                        is-aabnormal renal corpuscle morphology
                                                is-aabnormal renal glomerular capsule morphology
                                                        is-aabnormal glomerular capsule visceral layer morphology
                                                                is-aabnormal podocyte morphology
                                                                        is-aabnormal podocyte foot process morphology
                                                                                is-aabsent podocyte foot process
                                                                                is-afused podocyte foot processes
                                                                                is-apodocyte foot process effacement [MP:0008140] (67 genotypes, 67 annotations)


mammalian phenotype
        is-arenal/urinary system phenotype
                is-aabnormal renal/urinary system morphology
                        is-aabnormal kidney morphology
                                is-aabnormal nephron morphology
                                        is-aabnormal renal corpuscle morphology
                                                is-aabnormal renal glomerular capsule morphology
                                                        is-aabnormal glomerular capsule visceral layer morphology
                                                                is-aabnormal podocyte morphology
                                                                        is-aabnormal podocyte foot process morphology
                                                                                is-aabsent podocyte foot process
                                                                                is-afused podocyte foot processes
                                                                                is-apodocyte foot process effacement [MP:0008140] (67 genotypes, 67 annotations)

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last database update
11/11/2014
MGI 5.20
The Jackson Laboratory