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Mammalian Phenotype Browser
Term Detail
MP term:abnormal CD8-positive T cell number
Synonym: abnormal CD8+ T cell number
MP id: MP:0008077
Definition: anomaly in the number of the regulatory subset of T lymphocytes that are involved in MHC class I restricted interactions
Number of paths to term: 9

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal blood cell morphology/development
                                is-aabnormal hematopoiesis
                                        is-aabnormal hematopoietic cell number
                                                is-aabnormal leukocyte cell number
                                                        is-aabnormal lymphocyte cell number
                                                                is-aabnormal T cell number
                                                                        is-aabnormal CD4-positive T cell number +
                                                                        is-aabnormal CD8-positive T cell number [MP:0008077] (595 genotypes, 613 annotations)
                                                                                is-adecreased CD8-positive T cell number +
                                                                                is-aincreased CD8-positive T cell number +
                                                                        is-aabnormal gamma-delta T cell number +
                                                                        is-aabnormal intraepithelial T cell number +
                                                                        is-aabnormal memory T cell number +
                                                                        is-aabnormal NK T cell number +
                                                                        is-aabnormal regulatory T cell number +
                                                                        is-aabnormal T cell subpopulation ratio
                                                                        is-adecreased T cell number +
                                                                        is-aincreased T cell number +


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal blood cell morphology/development
                                is-aabnormal hematopoiesis
                                        is-aabnormal leukocyte morphology
                                                is-aabnormal leukocyte cell number
                                                        is-aabnormal lymphocyte cell number
                                                                is-aabnormal T cell number
                                                                        is-aabnormal CD4-positive T cell number +
                                                                        is-aabnormal CD8-positive T cell number [MP:0008077] (595 genotypes, 613 annotations)
                                                                                is-adecreased CD8-positive T cell number +
                                                                                is-aincreased CD8-positive T cell number +
                                                                        is-aabnormal gamma-delta T cell number +
                                                                        is-aabnormal intraepithelial T cell number +
                                                                        is-aabnormal memory T cell number +
                                                                        is-aabnormal NK T cell number +
                                                                        is-aabnormal regulatory T cell number +
                                                                        is-aabnormal T cell subpopulation ratio
                                                                        is-adecreased T cell number +
                                                                        is-aincreased T cell number +


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal blood cell morphology/development
                                is-aabnormal hematopoiesis
                                        is-aabnormal leukocyte morphology
                                                is-aabnormal mononuclear cell morphology
                                                        is-aabnormal lymphocyte morphology
                                                                is-aabnormal lymphocyte cell number
                                                                        is-aabnormal T cell number
                                                                                is-aabnormal CD4-positive T cell number +
                                                                                is-aabnormal CD8-positive T cell number [MP:0008077] (595 genotypes, 613 annotations)
                                                                                        is-adecreased CD8-positive T cell number +
                                                                                        is-aincreased CD8-positive T cell number +
                                                                                is-aabnormal gamma-delta T cell number +
                                                                                is-aabnormal intraepithelial T cell number +
                                                                                is-aabnormal memory T cell number +
                                                                                is-aabnormal NK T cell number +
                                                                                is-aabnormal regulatory T cell number +
                                                                                is-aabnormal T cell subpopulation ratio
                                                                                is-adecreased T cell number +
                                                                                is-aincreased T cell number +


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal blood cell morphology/development
                                is-aabnormal hematopoiesis
                                        is-aabnormal leukocyte morphology
                                                is-aabnormal mononuclear cell morphology
                                                        is-aabnormal lymphocyte morphology
                                                                is-aabnormal T cell morphology
                                                                        is-aabnormal effector T cell morphology
                                                                                is-aabnormal CD8-positive T cell morphology
                                                                                        is-aabnormal CD8 positive, alpha-beta intraepithelial T cell morphology
                                                                                        is-aabnormal CD8-positive T cell differentiation
                                                                                        is-aabnormal CD8-positive T cell number [MP:0008077] (595 genotypes, 613 annotations)
                                                                                                is-adecreased CD8-positive T cell number +
                                                                                                is-aincreased CD8-positive T cell number +
                                                                                        is-aabnormal CD8-positive, alpha-beta cytotoxic T cell morphology
                                                                                        is-aabnormal CD8-positive, alpha-beta memory T cell morphology +
                                                                                        is-aabnormal CD8-positive, alpha-beta regulatory T cell morphology
                                                                                        is-aabnormal Tc17 cell morphology +


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal blood cell morphology/development
                                is-aabnormal hematopoiesis
                                        is-aabnormal leukocyte morphology
                                                is-aabnormal mononuclear cell morphology
                                                        is-aabnormal lymphocyte morphology
                                                                is-aabnormal T cell morphology
                                                                        is-aabnormal T cell number
                                                                                is-aabnormal CD4-positive T cell number +
                                                                                is-aabnormal CD8-positive T cell number [MP:0008077] (595 genotypes, 613 annotations)
                                                                                        is-adecreased CD8-positive T cell number +
                                                                                        is-aincreased CD8-positive T cell number +
                                                                                is-aabnormal gamma-delta T cell number +
                                                                                is-aabnormal intraepithelial T cell number +
                                                                                is-aabnormal memory T cell number +
                                                                                is-aabnormal NK T cell number +
                                                                                is-aabnormal regulatory T cell number +
                                                                                is-aabnormal T cell subpopulation ratio
                                                                                is-adecreased T cell number +
                                                                                is-aincreased T cell number +


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal leukocyte cell number
                                                is-aabnormal lymphocyte cell number
                                                        is-aabnormal T cell number
                                                                is-aabnormal CD4-positive T cell number +
                                                                is-aabnormal CD8-positive T cell number [MP:0008077] (595 genotypes, 613 annotations)
                                                                        is-adecreased CD8-positive T cell number +
                                                                        is-aincreased CD8-positive T cell number +
                                                                is-aabnormal gamma-delta T cell number +
                                                                is-aabnormal intraepithelial T cell number +
                                                                is-aabnormal memory T cell number +
                                                                is-aabnormal NK T cell number +
                                                                is-aabnormal regulatory T cell number +
                                                                is-aabnormal T cell subpopulation ratio
                                                                is-adecreased T cell number +
                                                                is-aincreased T cell number +


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal mononuclear cell morphology
                                                is-aabnormal lymphocyte morphology
                                                        is-aabnormal lymphocyte cell number
                                                                is-aabnormal T cell number
                                                                        is-aabnormal CD4-positive T cell number +
                                                                        is-aabnormal CD8-positive T cell number [MP:0008077] (595 genotypes, 613 annotations)
                                                                                is-adecreased CD8-positive T cell number +
                                                                                is-aincreased CD8-positive T cell number +
                                                                        is-aabnormal gamma-delta T cell number +
                                                                        is-aabnormal intraepithelial T cell number +
                                                                        is-aabnormal memory T cell number +
                                                                        is-aabnormal NK T cell number +
                                                                        is-aabnormal regulatory T cell number +
                                                                        is-aabnormal T cell subpopulation ratio
                                                                        is-adecreased T cell number +
                                                                        is-aincreased T cell number +


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal mononuclear cell morphology
                                                is-aabnormal lymphocyte morphology
                                                        is-aabnormal T cell morphology
                                                                is-aabnormal effector T cell morphology
                                                                        is-aabnormal CD8-positive T cell morphology
                                                                                is-aabnormal CD8 positive, alpha-beta intraepithelial T cell morphology
                                                                                is-aabnormal CD8-positive T cell differentiation
                                                                                is-aabnormal CD8-positive T cell number [MP:0008077] (595 genotypes, 613 annotations)
                                                                                        is-adecreased CD8-positive T cell number +
                                                                                        is-aincreased CD8-positive T cell number +
                                                                                is-aabnormal CD8-positive, alpha-beta cytotoxic T cell morphology
                                                                                is-aabnormal CD8-positive, alpha-beta memory T cell morphology +
                                                                                is-aabnormal CD8-positive, alpha-beta regulatory T cell morphology
                                                                                is-aabnormal Tc17 cell morphology +


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal mononuclear cell morphology
                                                is-aabnormal lymphocyte morphology
                                                        is-aabnormal T cell morphology
                                                                is-aabnormal T cell number
                                                                        is-aabnormal CD4-positive T cell number +
                                                                        is-aabnormal CD8-positive T cell number [MP:0008077] (595 genotypes, 613 annotations)
                                                                                is-adecreased CD8-positive T cell number +
                                                                                is-aincreased CD8-positive T cell number +
                                                                        is-aabnormal gamma-delta T cell number +
                                                                        is-aabnormal intraepithelial T cell number +
                                                                        is-aabnormal memory T cell number +
                                                                        is-aabnormal NK T cell number +
                                                                        is-aabnormal regulatory T cell number +
                                                                        is-aabnormal T cell subpopulation ratio
                                                                        is-adecreased T cell number +
                                                                        is-aincreased T cell number +

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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory