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Mammalian Phenotype Browser
Term Detail
MP term:retinal ganglion cell degeneration
MP id: MP:0008067
Definition: degeneration or loss of ganglion neurons located in the innermost nuclear layer of the retina of that receive visual information from photoreceptors via various intermediate cells such as bipolar cells, amacrine cells, and horizontal cells; axons from these cells form the optic nerve and connect mainly to the lateral geniculate nucleus (LGN) and to the suprachiasmatic nucleus in the brain
Number of paths to term: 5

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-anervous system phenotype
                is-aabnormal nervous system morphology
                        is-aabnormal neuron morphology
                                is-aabnormal sensory neuron morphology
                                        is-aabnormal retinal ganglion cell morphology
                                                is-adecreased retinal ganglion cell number +
                                                is-aincreased retinal ganglion cell number
                                                is-aretinal ganglion cell degeneration [MP:0008067] (25 genotypes, 25 annotations)


mammalian phenotype
        is-anervous system phenotype
                is-aabnormal nervous system morphology
                        is-aabnormal neuron morphology
                                is-aneuron degeneration
                                        is-aamacrine cell degeneration
                                        is-acochlear hair cell degeneration +
                                        is-ahippocampal neuron degeneration
                                        is-amotor neuron degeneration
                                        is-aPurkinje cell degeneration +
                                        is-aretinal ganglion cell degeneration [MP:0008067] (25 genotypes, 25 annotations)
                                        is-aretinal photoreceptor degeneration +
                                        is-avestibular hair cell degeneration


mammalian phenotype
        is-anervous system phenotype
                is-aabnormal nervous system morphology
                        is-aabnormal somatic nervous system morphology
                                is-aabnormal somatic sensory system morphology
                                        is-aabnormal sensory neuron morphology
                                                is-aabnormal retinal ganglion cell morphology
                                                        is-adecreased retinal ganglion cell number +
                                                        is-aincreased retinal ganglion cell number
                                                        is-aretinal ganglion cell degeneration [MP:0008067] (25 genotypes, 25 annotations)


mammalian phenotype
        is-anervous system phenotype
                is-aabnormal nervous system morphology
                        is-aneurodegeneration
                                is-aneuron degeneration
                                        is-aamacrine cell degeneration
                                        is-acochlear hair cell degeneration +
                                        is-ahippocampal neuron degeneration
                                        is-amotor neuron degeneration
                                        is-aPurkinje cell degeneration +
                                        is-aretinal ganglion cell degeneration [MP:0008067] (25 genotypes, 25 annotations)
                                        is-aretinal photoreceptor degeneration +
                                        is-avestibular hair cell degeneration


mammalian phenotype
        is-avision/eye phenotype
                is-aabnormal eye morphology
                        is-aabnormal posterior eye segment morphology
                                is-aabnormal ocular fundus morphology
                                        is-aabnormal retina morphology
                                                is-aabnormal retinal layer morphology
                                                        is-aabnormal retinal neuronal layer morphology
                                                                is-aabnormal retinal ganglion layer morphology
                                                                        is-aabnormal retinal ganglion cell morphology
                                                                                is-adecreased retinal ganglion cell number +
                                                                                is-aincreased retinal ganglion cell number
                                                                                is-aretinal ganglion cell degeneration [MP:0008067] (25 genotypes, 25 annotations)

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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory