MGI 5.13 - Phenotype Browser

Mammalian Phenotype Browser
Term Detail

MP term:	decreased NK cell number
Synonym:	decreased natural killer cell number
Synonym:	reduced natural killer cell number
Synonym:	reduced NK cell number
MP id:	MP:0008045
Definition:	reduction in the number of lymphocytes that can spontaneously kill a variety of target cells without prior antigenic activation via germline encoded activation receptors, and also regulate immune responses via cytokine release and direct contact with other cells
Number of paths to term:	22

denotes an 'is-a' relationship
denotes a 'part-of' relationship

mammalian phenotype

hematopoietic system phenotype

abnormal hematopoietic system morphology/development

abnormal blood cell morphology/development

abnormal hematopoiesis

abnormal hematopoietic cell number

abnormal leukocyte cell number

abnormal lymphocyte cell number

abnormal NK cell number

decreased NK cell number [MP:0008045] (112 genotypes, 113 annotations)

absent NK cells +

increased NK cell number

mammalian phenotype

hematopoietic system phenotype

abnormal hematopoietic system morphology/development

abnormal blood cell morphology/development

abnormal hematopoiesis

abnormal hematopoietic cell number

abnormal leukocyte cell number

abnormal lymphocyte cell number

decreased lymphocyte cell number

absent lymphocyte +

decreased B cell number +

decreased NK cell number [MP:0008045] (112 genotypes, 113 annotations)

absent NK cells +

decreased T cell number +

mammalian phenotype

hematopoietic system phenotype

abnormal hematopoietic system morphology/development

abnormal blood cell morphology/development

abnormal hematopoiesis

abnormal hematopoietic cell number

abnormal leukocyte cell number

decreased leukocyte cell number

decreased lymphocyte cell number

absent lymphocyte +

decreased B cell number +

decreased NK cell number [MP:0008045] (112 genotypes, 113 annotations)

absent NK cells +

decreased T cell number +

mammalian phenotype

hematopoietic system phenotype

abnormal hematopoietic system morphology/development

abnormal blood cell morphology/development

abnormal hematopoiesis

abnormal hematopoietic cell number

decreased hematopoietic cell number

decreased leukocyte cell number

decreased lymphocyte cell number

absent lymphocyte +

decreased B cell number +

decreased NK cell number [MP:0008045] (112 genotypes, 113 annotations)

absent NK cells +

decreased T cell number +

mammalian phenotype

hematopoietic system phenotype

abnormal hematopoietic system morphology/development

abnormal blood cell morphology/development

abnormal hematopoiesis

abnormal leukocyte morphology

abnormal leukocyte cell number

abnormal lymphocyte cell number

abnormal NK cell number

decreased NK cell number [MP:0008045] (112 genotypes, 113 annotations)

absent NK cells +

increased NK cell number

mammalian phenotype

hematopoietic system phenotype

abnormal hematopoietic system morphology/development

abnormal blood cell morphology/development

abnormal hematopoiesis

abnormal leukocyte morphology

abnormal leukocyte cell number

abnormal lymphocyte cell number

decreased lymphocyte cell number

absent lymphocyte +

decreased B cell number +

decreased NK cell number [MP:0008045] (112 genotypes, 113 annotations)

absent NK cells +

decreased T cell number +

mammalian phenotype

hematopoietic system phenotype

abnormal hematopoietic system morphology/development

abnormal blood cell morphology/development

abnormal hematopoiesis

abnormal leukocyte morphology

abnormal leukocyte cell number

decreased leukocyte cell number

decreased lymphocyte cell number

absent lymphocyte +

decreased B cell number +

decreased NK cell number [MP:0008045] (112 genotypes, 113 annotations)

absent NK cells +

decreased T cell number +

mammalian phenotype

hematopoietic system phenotype

abnormal hematopoietic system morphology/development

abnormal blood cell morphology/development

abnormal hematopoiesis

abnormal leukocyte morphology

abnormal mononuclear cell morphology

abnormal lymphocyte morphology

abnormal lymphocyte cell number

abnormal NK cell number

decreased NK cell number [MP:0008045] (112 genotypes, 113 annotations)

absent NK cells +

increased NK cell number

mammalian phenotype

hematopoietic system phenotype

abnormal hematopoietic system morphology/development

abnormal blood cell morphology/development

abnormal hematopoiesis

abnormal leukocyte morphology

abnormal mononuclear cell morphology

abnormal lymphocyte morphology

abnormal lymphocyte cell number

decreased lymphocyte cell number

absent lymphocyte +

decreased B cell number +

decreased NK cell number [MP:0008045] (112 genotypes, 113 annotations)

absent NK cells +

decreased T cell number +

mammalian phenotype

hematopoietic system phenotype

abnormal hematopoietic system morphology/development

abnormal blood cell morphology/development

abnormal hematopoiesis

abnormal leukocyte morphology

abnormal mononuclear cell morphology

abnormal lymphocyte morphology

abnormal NK cell morphology

abnormal NK cell number

decreased NK cell number [MP:0008045] (112 genotypes, 113 annotations)

absent NK cells +

increased NK cell number

mammalian phenotype

hematopoietic system phenotype

abnormal hematopoietic system morphology/development

abnormal blood cell morphology/development

abnormal leukocyte morphology

abnormal leukocyte cell number

abnormal lymphocyte cell number

abnormal NK cell number

decreased NK cell number [MP:0008045] (112 genotypes, 113 annotations)

absent NK cells +

increased NK cell number

mammalian phenotype

hematopoietic system phenotype

abnormal hematopoietic system morphology/development

abnormal blood cell morphology/development

abnormal leukocyte morphology

abnormal leukocyte cell number

abnormal lymphocyte cell number

decreased lymphocyte cell number

absent lymphocyte +

decreased B cell number +

decreased NK cell number [MP:0008045] (112 genotypes, 113 annotations)

absent NK cells +

decreased T cell number +

mammalian phenotype

hematopoietic system phenotype

abnormal hematopoietic system morphology/development

abnormal blood cell morphology/development

abnormal leukocyte morphology

abnormal leukocyte cell number

decreased leukocyte cell number

decreased lymphocyte cell number

absent lymphocyte +

decreased B cell number +

decreased NK cell number [MP:0008045] (112 genotypes, 113 annotations)

absent NK cells +

decreased T cell number +

mammalian phenotype

hematopoietic system phenotype

abnormal hematopoietic system morphology/development

abnormal blood cell morphology/development

abnormal leukocyte morphology

abnormal mononuclear cell morphology

abnormal lymphocyte morphology

abnormal lymphocyte cell number

abnormal NK cell number

decreased NK cell number [MP:0008045] (112 genotypes, 113 annotations)

absent NK cells +

increased NK cell number

mammalian phenotype

hematopoietic system phenotype

abnormal hematopoietic system morphology/development

abnormal blood cell morphology/development

abnormal leukocyte morphology

abnormal mononuclear cell morphology

abnormal lymphocyte morphology

abnormal lymphocyte cell number

decreased lymphocyte cell number

absent lymphocyte +

decreased B cell number +

decreased NK cell number [MP:0008045] (112 genotypes, 113 annotations)

absent NK cells +

decreased T cell number +

mammalian phenotype

hematopoietic system phenotype

abnormal hematopoietic system morphology/development

abnormal blood cell morphology/development

abnormal leukocyte morphology

abnormal mononuclear cell morphology

abnormal lymphocyte morphology

abnormal NK cell morphology

abnormal NK cell number

decreased NK cell number [MP:0008045] (112 genotypes, 113 annotations)

absent NK cells +

increased NK cell number

mammalian phenotype

immune system phenotype

abnormal immune system morphology

abnormal immune system cell morphology

abnormal leukocyte morphology

abnormal leukocyte cell number

abnormal lymphocyte cell number

abnormal NK cell number

decreased NK cell number [MP:0008045] (112 genotypes, 113 annotations)

absent NK cells +

increased NK cell number

mammalian phenotype

immune system phenotype

abnormal immune system morphology

abnormal immune system cell morphology

abnormal leukocyte morphology

abnormal leukocyte cell number

abnormal lymphocyte cell number

decreased lymphocyte cell number

absent lymphocyte +

decreased B cell number +

decreased NK cell number [MP:0008045] (112 genotypes, 113 annotations)

absent NK cells +

decreased T cell number +

mammalian phenotype

immune system phenotype

abnormal immune system morphology

abnormal immune system cell morphology

abnormal leukocyte morphology

abnormal leukocyte cell number

decreased leukocyte cell number

decreased lymphocyte cell number

absent lymphocyte +

decreased B cell number +

decreased NK cell number [MP:0008045] (112 genotypes, 113 annotations)

absent NK cells +

decreased T cell number +

mammalian phenotype

immune system phenotype

abnormal immune system morphology

abnormal immune system cell morphology

abnormal leukocyte morphology

abnormal mononuclear cell morphology

abnormal lymphocyte morphology

abnormal lymphocyte cell number

abnormal NK cell number

decreased NK cell number [MP:0008045] (112 genotypes, 113 annotations)

absent NK cells +

increased NK cell number

mammalian phenotype

immune system phenotype

abnormal immune system morphology

abnormal immune system cell morphology

abnormal leukocyte morphology

abnormal mononuclear cell morphology

abnormal lymphocyte morphology

abnormal lymphocyte cell number

decreased lymphocyte cell number

absent lymphocyte +

decreased B cell number +

decreased NK cell number [MP:0008045] (112 genotypes, 113 annotations)

absent NK cells +

decreased T cell number +

mammalian phenotype

immune system phenotype

abnormal immune system morphology

abnormal immune system cell morphology

abnormal leukocyte morphology

abnormal mononuclear cell morphology

abnormal lymphocyte morphology

abnormal NK cell morphology

abnormal NK cell number

decreased NK cell number [MP:0008045] (112 genotypes, 113 annotations)

absent NK cells +

increased NK cell number

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Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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