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Mammalian Phenotype Browser
Term Detail
MP term:decreased NK cell number
Synonym: decreased natural killer cell number
Synonym: reduced natural killer cell number
Synonym: reduced NK cell number
MP id: MP:0008045
Definition: reduction in the number of lymphocytes that can spontaneously kill a variety of target cells without prior antigenic activation via germline encoded activation receptors, and also regulate immune responses via cytokine release and direct contact with other cells
Number of paths to term: 16

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal hematopoietic cell morphology
                                is-aabnormal hematopoietic cell number
                                        is-aabnormal leukocyte cell number
                                                is-aabnormal lymphocyte cell number
                                                        is-aabnormal NK cell number
                                                                is-aabnormal immature NK cell number +
                                                                is-aabnormal KLRG1-positive NK cell number +
                                                                is-aabnormal mature NK cell number +
                                                                is-aabnormal memory-marker NK cell number +
                                                                is-adecreased NK cell number [MP:0008045] (129 genotypes, 131 annotations)
                                                                        is-aabsent NK cells +
                                                                        is-adecreased immature NK cell number +
                                                                        is-adecreased KLRG1-positive NK cell number
                                                                        is-adecreased mature NK cell number +
                                                                        is-adecreased memory-marker NK cell number
                                                                        is-adecreased uterine NK cell number +
                                                                is-aincreased NK cell number +


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal hematopoietic cell morphology
                                is-aabnormal hematopoietic cell number
                                        is-aabnormal leukocyte cell number
                                                is-aabnormal lymphocyte cell number
                                                        is-adecreased lymphocyte cell number
                                                                is-aabsent lymphocyte +
                                                                is-adecreased B cell number +
                                                                is-adecreased large unstained cell number
                                                                is-adecreased NK cell number [MP:0008045] (129 genotypes, 131 annotations)
                                                                        is-aabsent NK cells +
                                                                        is-adecreased immature NK cell number +
                                                                        is-adecreased KLRG1-positive NK cell number
                                                                        is-adecreased mature NK cell number +
                                                                        is-adecreased memory-marker NK cell number
                                                                        is-adecreased uterine NK cell number +
                                                                is-adecreased T cell number +


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal hematopoietic cell morphology
                                is-aabnormal hematopoietic cell number
                                        is-aabnormal leukocyte cell number
                                                is-adecreased leukocyte cell number
                                                        is-adecreased lymphocyte cell number
                                                                is-aabsent lymphocyte +
                                                                is-adecreased B cell number +
                                                                is-adecreased large unstained cell number
                                                                is-adecreased NK cell number [MP:0008045] (129 genotypes, 131 annotations)
                                                                        is-aabsent NK cells +
                                                                        is-adecreased immature NK cell number +
                                                                        is-adecreased KLRG1-positive NK cell number
                                                                        is-adecreased mature NK cell number +
                                                                        is-adecreased memory-marker NK cell number
                                                                        is-adecreased uterine NK cell number +
                                                                is-adecreased T cell number +


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal hematopoietic cell morphology
                                is-aabnormal hematopoietic cell number
                                        is-adecreased hematopoietic cell number
                                                is-adecreased leukocyte cell number
                                                        is-adecreased lymphocyte cell number
                                                                is-aabsent lymphocyte +
                                                                is-adecreased B cell number +
                                                                is-adecreased large unstained cell number
                                                                is-adecreased NK cell number [MP:0008045] (129 genotypes, 131 annotations)
                                                                        is-aabsent NK cells +
                                                                        is-adecreased immature NK cell number +
                                                                        is-adecreased KLRG1-positive NK cell number
                                                                        is-adecreased mature NK cell number +
                                                                        is-adecreased memory-marker NK cell number
                                                                        is-adecreased uterine NK cell number +
                                                                is-adecreased T cell number +


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal hematopoietic cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal leukocyte cell number
                                                is-aabnormal lymphocyte cell number
                                                        is-aabnormal NK cell number
                                                                is-aabnormal immature NK cell number +
                                                                is-aabnormal KLRG1-positive NK cell number +
                                                                is-aabnormal mature NK cell number +
                                                                is-aabnormal memory-marker NK cell number +
                                                                is-adecreased NK cell number [MP:0008045] (129 genotypes, 131 annotations)
                                                                        is-aabsent NK cells +
                                                                        is-adecreased immature NK cell number +
                                                                        is-adecreased KLRG1-positive NK cell number
                                                                        is-adecreased mature NK cell number +
                                                                        is-adecreased memory-marker NK cell number
                                                                        is-adecreased uterine NK cell number +
                                                                is-aincreased NK cell number +


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal hematopoietic cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal leukocyte cell number
                                                is-aabnormal lymphocyte cell number
                                                        is-adecreased lymphocyte cell number
                                                                is-aabsent lymphocyte +
                                                                is-adecreased B cell number +
                                                                is-adecreased large unstained cell number
                                                                is-adecreased NK cell number [MP:0008045] (129 genotypes, 131 annotations)
                                                                        is-aabsent NK cells +
                                                                        is-adecreased immature NK cell number +
                                                                        is-adecreased KLRG1-positive NK cell number
                                                                        is-adecreased mature NK cell number +
                                                                        is-adecreased memory-marker NK cell number
                                                                        is-adecreased uterine NK cell number +
                                                                is-adecreased T cell number +


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal hematopoietic cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal leukocyte cell number
                                                is-adecreased leukocyte cell number
                                                        is-adecreased lymphocyte cell number
                                                                is-aabsent lymphocyte +
                                                                is-adecreased B cell number +
                                                                is-adecreased large unstained cell number
                                                                is-adecreased NK cell number [MP:0008045] (129 genotypes, 131 annotations)
                                                                        is-aabsent NK cells +
                                                                        is-adecreased immature NK cell number +
                                                                        is-adecreased KLRG1-positive NK cell number
                                                                        is-adecreased mature NK cell number +
                                                                        is-adecreased memory-marker NK cell number
                                                                        is-adecreased uterine NK cell number +
                                                                is-adecreased T cell number +


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal hematopoietic cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal mononuclear cell morphology
                                                is-aabnormal lymphocyte morphology
                                                        is-aabnormal lymphocyte cell number
                                                                is-aabnormal NK cell number
                                                                        is-aabnormal immature NK cell number +
                                                                        is-aabnormal KLRG1-positive NK cell number +
                                                                        is-aabnormal mature NK cell number +
                                                                        is-aabnormal memory-marker NK cell number +
                                                                        is-adecreased NK cell number [MP:0008045] (129 genotypes, 131 annotations)
                                                                                is-aabsent NK cells +
                                                                                is-adecreased immature NK cell number +
                                                                                is-adecreased KLRG1-positive NK cell number
                                                                                is-adecreased mature NK cell number +
                                                                                is-adecreased memory-marker NK cell number
                                                                                is-adecreased uterine NK cell number +
                                                                        is-aincreased NK cell number +


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal hematopoietic cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal mononuclear cell morphology
                                                is-aabnormal lymphocyte morphology
                                                        is-aabnormal lymphocyte cell number
                                                                is-adecreased lymphocyte cell number
                                                                        is-aabsent lymphocyte +
                                                                        is-adecreased B cell number +
                                                                        is-adecreased large unstained cell number
                                                                        is-adecreased NK cell number [MP:0008045] (129 genotypes, 131 annotations)
                                                                                is-aabsent NK cells +
                                                                                is-adecreased immature NK cell number +
                                                                                is-adecreased KLRG1-positive NK cell number
                                                                                is-adecreased mature NK cell number +
                                                                                is-adecreased memory-marker NK cell number
                                                                                is-adecreased uterine NK cell number +
                                                                        is-adecreased T cell number +


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal hematopoietic cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal mononuclear cell morphology
                                                is-aabnormal lymphocyte morphology
                                                        is-aabnormal NK cell morphology
                                                                is-aabnormal NK cell number
                                                                        is-aabnormal immature NK cell number +
                                                                        is-aabnormal KLRG1-positive NK cell number +
                                                                        is-aabnormal mature NK cell number +
                                                                        is-aabnormal memory-marker NK cell number +
                                                                        is-adecreased NK cell number [MP:0008045] (129 genotypes, 131 annotations)
                                                                                is-aabsent NK cells +
                                                                                is-adecreased immature NK cell number +
                                                                                is-adecreased KLRG1-positive NK cell number
                                                                                is-adecreased mature NK cell number +
                                                                                is-adecreased memory-marker NK cell number
                                                                                is-adecreased uterine NK cell number +
                                                                        is-aincreased NK cell number +


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal leukocyte cell number
                                                is-aabnormal lymphocyte cell number
                                                        is-aabnormal NK cell number
                                                                is-aabnormal immature NK cell number +
                                                                is-aabnormal KLRG1-positive NK cell number +
                                                                is-aabnormal mature NK cell number +
                                                                is-aabnormal memory-marker NK cell number +
                                                                is-adecreased NK cell number [MP:0008045] (129 genotypes, 131 annotations)
                                                                        is-aabsent NK cells +
                                                                        is-adecreased immature NK cell number +
                                                                        is-adecreased KLRG1-positive NK cell number
                                                                        is-adecreased mature NK cell number +
                                                                        is-adecreased memory-marker NK cell number
                                                                        is-adecreased uterine NK cell number +
                                                                is-aincreased NK cell number +


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal leukocyte cell number
                                                is-aabnormal lymphocyte cell number
                                                        is-adecreased lymphocyte cell number
                                                                is-aabsent lymphocyte +
                                                                is-adecreased B cell number +
                                                                is-adecreased large unstained cell number
                                                                is-adecreased NK cell number [MP:0008045] (129 genotypes, 131 annotations)
                                                                        is-aabsent NK cells +
                                                                        is-adecreased immature NK cell number +
                                                                        is-adecreased KLRG1-positive NK cell number
                                                                        is-adecreased mature NK cell number +
                                                                        is-adecreased memory-marker NK cell number
                                                                        is-adecreased uterine NK cell number +
                                                                is-adecreased T cell number +


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal leukocyte cell number
                                                is-adecreased leukocyte cell number
                                                        is-adecreased lymphocyte cell number
                                                                is-aabsent lymphocyte +
                                                                is-adecreased B cell number +
                                                                is-adecreased large unstained cell number
                                                                is-adecreased NK cell number [MP:0008045] (129 genotypes, 131 annotations)
                                                                        is-aabsent NK cells +
                                                                        is-adecreased immature NK cell number +
                                                                        is-adecreased KLRG1-positive NK cell number
                                                                        is-adecreased mature NK cell number +
                                                                        is-adecreased memory-marker NK cell number
                                                                        is-adecreased uterine NK cell number +
                                                                is-adecreased T cell number +


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal mononuclear cell morphology
                                                is-aabnormal lymphocyte morphology
                                                        is-aabnormal lymphocyte cell number
                                                                is-aabnormal NK cell number
                                                                        is-aabnormal immature NK cell number +
                                                                        is-aabnormal KLRG1-positive NK cell number +
                                                                        is-aabnormal mature NK cell number +
                                                                        is-aabnormal memory-marker NK cell number +
                                                                        is-adecreased NK cell number [MP:0008045] (129 genotypes, 131 annotations)
                                                                                is-aabsent NK cells +
                                                                                is-adecreased immature NK cell number +
                                                                                is-adecreased KLRG1-positive NK cell number
                                                                                is-adecreased mature NK cell number +
                                                                                is-adecreased memory-marker NK cell number
                                                                                is-adecreased uterine NK cell number +
                                                                        is-aincreased NK cell number +


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal mononuclear cell morphology
                                                is-aabnormal lymphocyte morphology
                                                        is-aabnormal lymphocyte cell number
                                                                is-adecreased lymphocyte cell number
                                                                        is-aabsent lymphocyte +
                                                                        is-adecreased B cell number +
                                                                        is-adecreased large unstained cell number
                                                                        is-adecreased NK cell number [MP:0008045] (129 genotypes, 131 annotations)
                                                                                is-aabsent NK cells +
                                                                                is-adecreased immature NK cell number +
                                                                                is-adecreased KLRG1-positive NK cell number
                                                                                is-adecreased mature NK cell number +
                                                                                is-adecreased memory-marker NK cell number
                                                                                is-adecreased uterine NK cell number +
                                                                        is-adecreased T cell number +


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal mononuclear cell morphology
                                                is-aabnormal lymphocyte morphology
                                                        is-aabnormal NK cell morphology
                                                                is-aabnormal NK cell number
                                                                        is-aabnormal immature NK cell number +
                                                                        is-aabnormal KLRG1-positive NK cell number +
                                                                        is-aabnormal mature NK cell number +
                                                                        is-aabnormal memory-marker NK cell number +
                                                                        is-adecreased NK cell number [MP:0008045] (129 genotypes, 131 annotations)
                                                                                is-aabsent NK cells +
                                                                                is-adecreased immature NK cell number +
                                                                                is-adecreased KLRG1-positive NK cell number
                                                                                is-adecreased mature NK cell number +
                                                                                is-adecreased memory-marker NK cell number
                                                                                is-adecreased uterine NK cell number +
                                                                        is-aincreased NK cell number +

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last database update
08/18/2015
MGI 6.0
The Jackson Laboratory