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Mammalian Phenotype Browser
Term Detail
MP term:decreased NK cell number
Synonym: decreased natural killer cell number
Synonym: reduced natural killer cell number
Synonym: reduced NK cell number
MP id: MP:0008045
Definition: reduction in the number of lymphocytes that can spontaneously kill a variety of target cells without prior antigenic activation via germline encoded activation receptors, and also regulate immune responses via cytokine release and direct contact with other cells
Number of paths to term: 16

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal blood cell morphology/development
                                is-aabnormal hematopoiesis
                                        is-aabnormal hematopoietic cell number
                                                is-aabnormal leukocyte cell number
                                                        is-aabnormal lymphocyte cell number
                                                                is-aabnormal NK cell number
                                                                        is-aabnormal KLRG1-positive NK cell number +
                                                                        is-adecreased NK cell number [MP:0008045] (120 genotypes, 121 annotations)
                                                                                is-aabsent NK cells +
                                                                                is-adecreased KLRG1-positive NK cell number
                                                                        is-aincreased NK cell number +


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal blood cell morphology/development
                                is-aabnormal hematopoiesis
                                        is-aabnormal hematopoietic cell number
                                                is-aabnormal leukocyte cell number
                                                        is-aabnormal lymphocyte cell number
                                                                is-adecreased lymphocyte cell number
                                                                        is-aabsent lymphocyte +
                                                                        is-adecreased B cell number +
                                                                        is-adecreased large unstained cell number
                                                                        is-adecreased NK cell number [MP:0008045] (120 genotypes, 121 annotations)
                                                                                is-aabsent NK cells +
                                                                                is-adecreased KLRG1-positive NK cell number
                                                                        is-adecreased T cell number +


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal blood cell morphology/development
                                is-aabnormal hematopoiesis
                                        is-aabnormal hematopoietic cell number
                                                is-aabnormal leukocyte cell number
                                                        is-adecreased leukocyte cell number
                                                                is-adecreased lymphocyte cell number
                                                                        is-aabsent lymphocyte +
                                                                        is-adecreased B cell number +
                                                                        is-adecreased large unstained cell number
                                                                        is-adecreased NK cell number [MP:0008045] (120 genotypes, 121 annotations)
                                                                                is-aabsent NK cells +
                                                                                is-adecreased KLRG1-positive NK cell number
                                                                        is-adecreased T cell number +


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal blood cell morphology/development
                                is-aabnormal hematopoiesis
                                        is-aabnormal hematopoietic cell number
                                                is-adecreased hematopoietic cell number
                                                        is-adecreased leukocyte cell number
                                                                is-adecreased lymphocyte cell number
                                                                        is-aabsent lymphocyte +
                                                                        is-adecreased B cell number +
                                                                        is-adecreased large unstained cell number
                                                                        is-adecreased NK cell number [MP:0008045] (120 genotypes, 121 annotations)
                                                                                is-aabsent NK cells +
                                                                                is-adecreased KLRG1-positive NK cell number
                                                                        is-adecreased T cell number +


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal blood cell morphology/development
                                is-aabnormal hematopoiesis
                                        is-aabnormal leukocyte morphology
                                                is-aabnormal leukocyte cell number
                                                        is-aabnormal lymphocyte cell number
                                                                is-aabnormal NK cell number
                                                                        is-aabnormal KLRG1-positive NK cell number +
                                                                        is-adecreased NK cell number [MP:0008045] (120 genotypes, 121 annotations)
                                                                                is-aabsent NK cells +
                                                                                is-adecreased KLRG1-positive NK cell number
                                                                        is-aincreased NK cell number +


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal blood cell morphology/development
                                is-aabnormal hematopoiesis
                                        is-aabnormal leukocyte morphology
                                                is-aabnormal leukocyte cell number
                                                        is-aabnormal lymphocyte cell number
                                                                is-adecreased lymphocyte cell number
                                                                        is-aabsent lymphocyte +
                                                                        is-adecreased B cell number +
                                                                        is-adecreased large unstained cell number
                                                                        is-adecreased NK cell number [MP:0008045] (120 genotypes, 121 annotations)
                                                                                is-aabsent NK cells +
                                                                                is-adecreased KLRG1-positive NK cell number
                                                                        is-adecreased T cell number +


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal blood cell morphology/development
                                is-aabnormal hematopoiesis
                                        is-aabnormal leukocyte morphology
                                                is-aabnormal leukocyte cell number
                                                        is-adecreased leukocyte cell number
                                                                is-adecreased lymphocyte cell number
                                                                        is-aabsent lymphocyte +
                                                                        is-adecreased B cell number +
                                                                        is-adecreased large unstained cell number
                                                                        is-adecreased NK cell number [MP:0008045] (120 genotypes, 121 annotations)
                                                                                is-aabsent NK cells +
                                                                                is-adecreased KLRG1-positive NK cell number
                                                                        is-adecreased T cell number +


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal blood cell morphology/development
                                is-aabnormal hematopoiesis
                                        is-aabnormal leukocyte morphology
                                                is-aabnormal mononuclear cell morphology
                                                        is-aabnormal lymphocyte morphology
                                                                is-aabnormal lymphocyte cell number
                                                                        is-aabnormal NK cell number
                                                                                is-aabnormal KLRG1-positive NK cell number +
                                                                                is-adecreased NK cell number [MP:0008045] (120 genotypes, 121 annotations)
                                                                                        is-aabsent NK cells +
                                                                                        is-adecreased KLRG1-positive NK cell number
                                                                                is-aincreased NK cell number +


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal blood cell morphology/development
                                is-aabnormal hematopoiesis
                                        is-aabnormal leukocyte morphology
                                                is-aabnormal mononuclear cell morphology
                                                        is-aabnormal lymphocyte morphology
                                                                is-aabnormal lymphocyte cell number
                                                                        is-adecreased lymphocyte cell number
                                                                                is-aabsent lymphocyte +
                                                                                is-adecreased B cell number +
                                                                                is-adecreased large unstained cell number
                                                                                is-adecreased NK cell number [MP:0008045] (120 genotypes, 121 annotations)
                                                                                        is-aabsent NK cells +
                                                                                        is-adecreased KLRG1-positive NK cell number
                                                                                is-adecreased T cell number +


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal blood cell morphology/development
                                is-aabnormal hematopoiesis
                                        is-aabnormal leukocyte morphology
                                                is-aabnormal mononuclear cell morphology
                                                        is-aabnormal lymphocyte morphology
                                                                is-aabnormal NK cell morphology
                                                                        is-aabnormal NK cell number
                                                                                is-aabnormal KLRG1-positive NK cell number +
                                                                                is-adecreased NK cell number [MP:0008045] (120 genotypes, 121 annotations)
                                                                                        is-aabsent NK cells +
                                                                                        is-adecreased KLRG1-positive NK cell number
                                                                                is-aincreased NK cell number +


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal leukocyte cell number
                                                is-aabnormal lymphocyte cell number
                                                        is-aabnormal NK cell number
                                                                is-aabnormal KLRG1-positive NK cell number +
                                                                is-adecreased NK cell number [MP:0008045] (120 genotypes, 121 annotations)
                                                                        is-aabsent NK cells +
                                                                        is-adecreased KLRG1-positive NK cell number
                                                                is-aincreased NK cell number +


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal leukocyte cell number
                                                is-aabnormal lymphocyte cell number
                                                        is-adecreased lymphocyte cell number
                                                                is-aabsent lymphocyte +
                                                                is-adecreased B cell number +
                                                                is-adecreased large unstained cell number
                                                                is-adecreased NK cell number [MP:0008045] (120 genotypes, 121 annotations)
                                                                        is-aabsent NK cells +
                                                                        is-adecreased KLRG1-positive NK cell number
                                                                is-adecreased T cell number +


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal leukocyte cell number
                                                is-adecreased leukocyte cell number
                                                        is-adecreased lymphocyte cell number
                                                                is-aabsent lymphocyte +
                                                                is-adecreased B cell number +
                                                                is-adecreased large unstained cell number
                                                                is-adecreased NK cell number [MP:0008045] (120 genotypes, 121 annotations)
                                                                        is-aabsent NK cells +
                                                                        is-adecreased KLRG1-positive NK cell number
                                                                is-adecreased T cell number +


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal mononuclear cell morphology
                                                is-aabnormal lymphocyte morphology
                                                        is-aabnormal lymphocyte cell number
                                                                is-aabnormal NK cell number
                                                                        is-aabnormal KLRG1-positive NK cell number +
                                                                        is-adecreased NK cell number [MP:0008045] (120 genotypes, 121 annotations)
                                                                                is-aabsent NK cells +
                                                                                is-adecreased KLRG1-positive NK cell number
                                                                        is-aincreased NK cell number +


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal mononuclear cell morphology
                                                is-aabnormal lymphocyte morphology
                                                        is-aabnormal lymphocyte cell number
                                                                is-adecreased lymphocyte cell number
                                                                        is-aabsent lymphocyte +
                                                                        is-adecreased B cell number +
                                                                        is-adecreased large unstained cell number
                                                                        is-adecreased NK cell number [MP:0008045] (120 genotypes, 121 annotations)
                                                                                is-aabsent NK cells +
                                                                                is-adecreased KLRG1-positive NK cell number
                                                                        is-adecreased T cell number +


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal mononuclear cell morphology
                                                is-aabnormal lymphocyte morphology
                                                        is-aabnormal NK cell morphology
                                                                is-aabnormal NK cell number
                                                                        is-aabnormal KLRG1-positive NK cell number +
                                                                        is-adecreased NK cell number [MP:0008045] (120 genotypes, 121 annotations)
                                                                                is-aabsent NK cells +
                                                                                is-adecreased KLRG1-positive NK cell number
                                                                        is-aincreased NK cell number +

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last database update
08/26/2014
MGI 5.19
The Jackson Laboratory