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Mammalian Phenotype Browser
Term Detail
MP term:increased NK cell number
Synonym: increased natural killer cell number
MP id: MP:0008044
Definition: greater number of lymphocytes that can spontaneously kill a variety of target cells without prior antigenic activation via germline encoded activation receptors, and also regulate immune responses via cytokine release and direct contact with other cells
Number of paths to term: 16

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal hematopoietic cell morphology
                                is-aabnormal hematopoietic cell number
                                        is-aabnormal leukocyte cell number
                                                is-aabnormal lymphocyte cell number
                                                        is-aabnormal NK cell number
                                                                is-aabnormal immature NK cell number +
                                                                is-aabnormal KLRG1-positive NK cell number +
                                                                is-aabnormal mature NK cell number +
                                                                is-aabnormal memory-marker NK cell number +
                                                                is-adecreased NK cell number +
                                                                is-aincreased NK cell number [MP:0008044] (52 genotypes, 53 annotations)
                                                                        is-aincreased immature NK cell number +
                                                                        is-aincreased KLRG1-positive NK cell number
                                                                        is-aincreased mature NK cell number +
                                                                        is-aincreased memory-marker NK cell number
                                                                        is-aincreased uterine NK cell number


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal hematopoietic cell morphology
                                is-aabnormal hematopoietic cell number
                                        is-aabnormal leukocyte cell number
                                                is-aabnormal lymphocyte cell number
                                                        is-aincreased lymphocyte cell number
                                                                is-aincreased B cell number +
                                                                is-aincreased large unstained cell number
                                                                is-aincreased NK cell number [MP:0008044] (52 genotypes, 53 annotations)
                                                                        is-aincreased immature NK cell number +
                                                                        is-aincreased KLRG1-positive NK cell number
                                                                        is-aincreased mature NK cell number +
                                                                        is-aincreased memory-marker NK cell number
                                                                        is-aincreased uterine NK cell number
                                                                is-aincreased T cell number +


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal hematopoietic cell morphology
                                is-aabnormal hematopoietic cell number
                                        is-aabnormal leukocyte cell number
                                                is-aincreased leukocyte cell number
                                                        is-aincreased lymphocyte cell number
                                                                is-aincreased B cell number +
                                                                is-aincreased large unstained cell number
                                                                is-aincreased NK cell number [MP:0008044] (52 genotypes, 53 annotations)
                                                                        is-aincreased immature NK cell number +
                                                                        is-aincreased KLRG1-positive NK cell number
                                                                        is-aincreased mature NK cell number +
                                                                        is-aincreased memory-marker NK cell number
                                                                        is-aincreased uterine NK cell number
                                                                is-aincreased T cell number +


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal hematopoietic cell morphology
                                is-aabnormal hematopoietic cell number
                                        is-aincreased hematopoietic cell number
                                                is-aincreased leukocyte cell number
                                                        is-aincreased lymphocyte cell number
                                                                is-aincreased B cell number +
                                                                is-aincreased large unstained cell number
                                                                is-aincreased NK cell number [MP:0008044] (52 genotypes, 53 annotations)
                                                                        is-aincreased immature NK cell number +
                                                                        is-aincreased KLRG1-positive NK cell number
                                                                        is-aincreased mature NK cell number +
                                                                        is-aincreased memory-marker NK cell number
                                                                        is-aincreased uterine NK cell number
                                                                is-aincreased T cell number +


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal hematopoietic cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal leukocyte cell number
                                                is-aabnormal lymphocyte cell number
                                                        is-aabnormal NK cell number
                                                                is-aabnormal immature NK cell number +
                                                                is-aabnormal KLRG1-positive NK cell number +
                                                                is-aabnormal mature NK cell number +
                                                                is-aabnormal memory-marker NK cell number +
                                                                is-adecreased NK cell number +
                                                                is-aincreased NK cell number [MP:0008044] (52 genotypes, 53 annotations)
                                                                        is-aincreased immature NK cell number +
                                                                        is-aincreased KLRG1-positive NK cell number
                                                                        is-aincreased mature NK cell number +
                                                                        is-aincreased memory-marker NK cell number
                                                                        is-aincreased uterine NK cell number


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal hematopoietic cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal leukocyte cell number
                                                is-aabnormal lymphocyte cell number
                                                        is-aincreased lymphocyte cell number
                                                                is-aincreased B cell number +
                                                                is-aincreased large unstained cell number
                                                                is-aincreased NK cell number [MP:0008044] (52 genotypes, 53 annotations)
                                                                        is-aincreased immature NK cell number +
                                                                        is-aincreased KLRG1-positive NK cell number
                                                                        is-aincreased mature NK cell number +
                                                                        is-aincreased memory-marker NK cell number
                                                                        is-aincreased uterine NK cell number
                                                                is-aincreased T cell number +


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal hematopoietic cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal leukocyte cell number
                                                is-aincreased leukocyte cell number
                                                        is-aincreased lymphocyte cell number
                                                                is-aincreased B cell number +
                                                                is-aincreased large unstained cell number
                                                                is-aincreased NK cell number [MP:0008044] (52 genotypes, 53 annotations)
                                                                        is-aincreased immature NK cell number +
                                                                        is-aincreased KLRG1-positive NK cell number
                                                                        is-aincreased mature NK cell number +
                                                                        is-aincreased memory-marker NK cell number
                                                                        is-aincreased uterine NK cell number
                                                                is-aincreased T cell number +


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal hematopoietic cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal mononuclear cell morphology
                                                is-aabnormal lymphocyte morphology
                                                        is-aabnormal lymphocyte cell number
                                                                is-aabnormal NK cell number
                                                                        is-aabnormal immature NK cell number +
                                                                        is-aabnormal KLRG1-positive NK cell number +
                                                                        is-aabnormal mature NK cell number +
                                                                        is-aabnormal memory-marker NK cell number +
                                                                        is-adecreased NK cell number +
                                                                        is-aincreased NK cell number [MP:0008044] (52 genotypes, 53 annotations)
                                                                                is-aincreased immature NK cell number +
                                                                                is-aincreased KLRG1-positive NK cell number
                                                                                is-aincreased mature NK cell number +
                                                                                is-aincreased memory-marker NK cell number
                                                                                is-aincreased uterine NK cell number


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal hematopoietic cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal mononuclear cell morphology
                                                is-aabnormal lymphocyte morphology
                                                        is-aabnormal lymphocyte cell number
                                                                is-aincreased lymphocyte cell number
                                                                        is-aincreased B cell number +
                                                                        is-aincreased large unstained cell number
                                                                        is-aincreased NK cell number [MP:0008044] (52 genotypes, 53 annotations)
                                                                                is-aincreased immature NK cell number +
                                                                                is-aincreased KLRG1-positive NK cell number
                                                                                is-aincreased mature NK cell number +
                                                                                is-aincreased memory-marker NK cell number
                                                                                is-aincreased uterine NK cell number
                                                                        is-aincreased T cell number +


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal hematopoietic cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal mononuclear cell morphology
                                                is-aabnormal lymphocyte morphology
                                                        is-aabnormal NK cell morphology
                                                                is-aabnormal NK cell number
                                                                        is-aabnormal immature NK cell number +
                                                                        is-aabnormal KLRG1-positive NK cell number +
                                                                        is-aabnormal mature NK cell number +
                                                                        is-aabnormal memory-marker NK cell number +
                                                                        is-adecreased NK cell number +
                                                                        is-aincreased NK cell number [MP:0008044] (52 genotypes, 53 annotations)
                                                                                is-aincreased immature NK cell number +
                                                                                is-aincreased KLRG1-positive NK cell number
                                                                                is-aincreased mature NK cell number +
                                                                                is-aincreased memory-marker NK cell number
                                                                                is-aincreased uterine NK cell number


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal leukocyte cell number
                                                is-aabnormal lymphocyte cell number
                                                        is-aabnormal NK cell number
                                                                is-aabnormal immature NK cell number +
                                                                is-aabnormal KLRG1-positive NK cell number +
                                                                is-aabnormal mature NK cell number +
                                                                is-aabnormal memory-marker NK cell number +
                                                                is-adecreased NK cell number +
                                                                is-aincreased NK cell number [MP:0008044] (52 genotypes, 53 annotations)
                                                                        is-aincreased immature NK cell number +
                                                                        is-aincreased KLRG1-positive NK cell number
                                                                        is-aincreased mature NK cell number +
                                                                        is-aincreased memory-marker NK cell number
                                                                        is-aincreased uterine NK cell number


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal leukocyte cell number
                                                is-aabnormal lymphocyte cell number
                                                        is-aincreased lymphocyte cell number
                                                                is-aincreased B cell number +
                                                                is-aincreased large unstained cell number
                                                                is-aincreased NK cell number [MP:0008044] (52 genotypes, 53 annotations)
                                                                        is-aincreased immature NK cell number +
                                                                        is-aincreased KLRG1-positive NK cell number
                                                                        is-aincreased mature NK cell number +
                                                                        is-aincreased memory-marker NK cell number
                                                                        is-aincreased uterine NK cell number
                                                                is-aincreased T cell number +


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal leukocyte cell number
                                                is-aincreased leukocyte cell number
                                                        is-aincreased lymphocyte cell number
                                                                is-aincreased B cell number +
                                                                is-aincreased large unstained cell number
                                                                is-aincreased NK cell number [MP:0008044] (52 genotypes, 53 annotations)
                                                                        is-aincreased immature NK cell number +
                                                                        is-aincreased KLRG1-positive NK cell number
                                                                        is-aincreased mature NK cell number +
                                                                        is-aincreased memory-marker NK cell number
                                                                        is-aincreased uterine NK cell number
                                                                is-aincreased T cell number +


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal mononuclear cell morphology
                                                is-aabnormal lymphocyte morphology
                                                        is-aabnormal lymphocyte cell number
                                                                is-aabnormal NK cell number
                                                                        is-aabnormal immature NK cell number +
                                                                        is-aabnormal KLRG1-positive NK cell number +
                                                                        is-aabnormal mature NK cell number +
                                                                        is-aabnormal memory-marker NK cell number +
                                                                        is-adecreased NK cell number +
                                                                        is-aincreased NK cell number [MP:0008044] (52 genotypes, 53 annotations)
                                                                                is-aincreased immature NK cell number +
                                                                                is-aincreased KLRG1-positive NK cell number
                                                                                is-aincreased mature NK cell number +
                                                                                is-aincreased memory-marker NK cell number
                                                                                is-aincreased uterine NK cell number


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal mononuclear cell morphology
                                                is-aabnormal lymphocyte morphology
                                                        is-aabnormal lymphocyte cell number
                                                                is-aincreased lymphocyte cell number
                                                                        is-aincreased B cell number +
                                                                        is-aincreased large unstained cell number
                                                                        is-aincreased NK cell number [MP:0008044] (52 genotypes, 53 annotations)
                                                                                is-aincreased immature NK cell number +
                                                                                is-aincreased KLRG1-positive NK cell number
                                                                                is-aincreased mature NK cell number +
                                                                                is-aincreased memory-marker NK cell number
                                                                                is-aincreased uterine NK cell number
                                                                        is-aincreased T cell number +


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal mononuclear cell morphology
                                                is-aabnormal lymphocyte morphology
                                                        is-aabnormal NK cell morphology
                                                                is-aabnormal NK cell number
                                                                        is-aabnormal immature NK cell number +
                                                                        is-aabnormal KLRG1-positive NK cell number +
                                                                        is-aabnormal mature NK cell number +
                                                                        is-aabnormal memory-marker NK cell number +
                                                                        is-adecreased NK cell number +
                                                                        is-aincreased NK cell number [MP:0008044] (52 genotypes, 53 annotations)
                                                                                is-aincreased immature NK cell number +
                                                                                is-aincreased KLRG1-positive NK cell number
                                                                                is-aincreased mature NK cell number +
                                                                                is-aincreased memory-marker NK cell number
                                                                                is-aincreased uterine NK cell number

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last database update
08/18/2015
MGI 6.0
The Jackson Laboratory