| MP term: | abnormal isthmic organizer morphology |
| MP id: | MP:0006174 |
| Definition: | any structural anomaly of the organizing signaling center that forms at the boundary between the midbrain and hindbrain and plays essential role in development of the midbrain and anterior hindbrain |
| Number of paths to term: | 2 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
nervous system phenotypeabnormal nervous system morphologyabnormal brain morphologyabnormal brain developmentabnormal cervical flexure morphologyabnormal embryonic neuroepithelial layer differentiationabnormal forebrain development +abnormal hindbrain development +abnormal isthmic organizer morphology [MP:0006174] (8 genotypes, 8 annotations)abnormal midbrain development +abnormal olfactory bulb development +abnormal primordial meninx morphologydecreased oligodendrocyte progenitor numberdelayed brain developmentexencephalyholoprosencephaly +hydroencephaly +increased oligodendrocyte progenitor numbernervous system phenotypeabnormal nervous system morphologyabnormal nervous system developmentabnormal brain developmentabnormal cervical flexure morphologyabnormal embryonic neuroepithelial layer differentiationabnormal forebrain development +abnormal hindbrain development +abnormal isthmic organizer morphology [MP:0006174] (8 genotypes, 8 annotations)abnormal midbrain development +abnormal olfactory bulb development +abnormal primordial meninx morphologydecreased oligodendrocyte progenitor numberdelayed brain developmentexencephalyholoprosencephaly +hydroencephaly +increased oligodendrocyte progenitor numberMouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/22/2013 MGI 5.13 |
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