| MP term: | abnormal Langerhans cell physiology |
| Synonym: | abnormal Langerhans cell function |
| MP id: | MP:0005362 |
| Definition: | atypical or failure of normal function of the stellate dendritic cell of myeloid origin, that appears clear on light microscopy and has a dark-staining, indented nucleus and characteristic inclusions (Birbeck granules) in the cytoplasm; Langerhans cells are found principally in the stratum spinosum of the epidermis, but they also occur in other stratified epithelia and have been identified in the lung, lymph nodes, spleen, and thymus |
| Number of paths to term: | 3 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
immune system phenotypeabnormal immune system physiologyabnormal adaptive immunityabnormal professional antigen presenting cell physiologyabnormal dendritic cell physiologyabnormal dendritic cell antigen presentation +abnormal dendritic cell chemotaxisabnormal Langerhans cell physiology [MP:0005362] (18 genotypes, 18 annotations)abnormal Langerhans cell antigen presentationabnormal plasmacytoid dendritic cell physiologyimmune system phenotypeabnormal immune system physiologyabnormal cell-mediated immunityabnormal professional antigen presenting cell physiologyabnormal dendritic cell physiologyabnormal dendritic cell antigen presentation +abnormal dendritic cell chemotaxisabnormal Langerhans cell physiology [MP:0005362] (18 genotypes, 18 annotations)abnormal Langerhans cell antigen presentationabnormal plasmacytoid dendritic cell physiologyimmune system phenotypeabnormal immune system physiologyabnormal immune cell physiologyabnormal professional antigen presenting cell physiologyabnormal dendritic cell physiologyabnormal dendritic cell antigen presentation +abnormal dendritic cell chemotaxisabnormal Langerhans cell physiology [MP:0005362] (18 genotypes, 18 annotations)abnormal Langerhans cell antigen presentationabnormal plasmacytoid dendritic cell physiologyMouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/08/2013 MGI 5.13 |
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