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Mammalian Phenotype Browser
Term Detail
MP term:decreased double-positive T cell number
Synonym: decreased CD4+CD8+ T cell count
Synonym: decreased CD4+CD8+ T cell numbers
Synonym: decreased double-positive T cell count
Synonym: decreased double positive T cell number
Synonym: decreased double-positive T cell numbers
Synonym: decreased double-positive T-cell numbers
Synonym: reduced CD4+CD8+ T cell count
Synonym: reduced CD4+CD8+ T cell numbers
Synonym: reduced double-positive T cell count
Synonym: reduced double positive T cell number
Synonym: reduced double-positive T cell numbers
Synonym: reduced double-positive T-cell numbers
MP id: MP:0005092
Definition: less than the expected number of the subset of T cells found in the thymus that express both CD4 and CD8
Number of paths to term: 22

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal blood cell morphology/development
                                is-aabnormal hematopoiesis
                                        is-aabnormal hematopoietic cell number
                                                is-aabnormal leukocyte cell number
                                                        is-aabnormal lymphocyte cell number
                                                                is-aabnormal T cell number
                                                                        is-adecreased T cell number
                                                                                is-aabsent T cells +
                                                                                is-adecreased activated T cell number
                                                                                is-adecreased alpha-beta T cell number +
                                                                                is-adecreased double-negative T cell number +
                                                                                is-adecreased double-positive T cell number [MP:0005092] (317 genotypes, 317 annotations)
                                                                                is-adecreased gamma-delta T cell number +
                                                                                is-adecreased memory T cell number +
                                                                                is-adecreased NK T cell number +
                                                                                is-adecreased regulatory T cell number +
                                                                                is-adecreased single-positive T cell number
                                                                                is-adecreased thymocyte number +


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal blood cell morphology/development
                                is-aabnormal hematopoiesis
                                        is-aabnormal hematopoietic cell number
                                                is-aabnormal leukocyte cell number
                                                        is-aabnormal lymphocyte cell number
                                                                is-adecreased lymphocyte cell number
                                                                        is-adecreased T cell number
                                                                                is-aabsent T cells +
                                                                                is-adecreased activated T cell number
                                                                                is-adecreased alpha-beta T cell number +
                                                                                is-adecreased double-negative T cell number +
                                                                                is-adecreased double-positive T cell number [MP:0005092] (317 genotypes, 317 annotations)
                                                                                is-adecreased gamma-delta T cell number +
                                                                                is-adecreased memory T cell number +
                                                                                is-adecreased NK T cell number +
                                                                                is-adecreased regulatory T cell number +
                                                                                is-adecreased single-positive T cell number
                                                                                is-adecreased thymocyte number +


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal blood cell morphology/development
                                is-aabnormal hematopoiesis
                                        is-aabnormal hematopoietic cell number
                                                is-aabnormal leukocyte cell number
                                                        is-adecreased leukocyte cell number
                                                                is-adecreased lymphocyte cell number
                                                                        is-adecreased T cell number
                                                                                is-aabsent T cells +
                                                                                is-adecreased activated T cell number
                                                                                is-adecreased alpha-beta T cell number +
                                                                                is-adecreased double-negative T cell number +
                                                                                is-adecreased double-positive T cell number [MP:0005092] (317 genotypes, 317 annotations)
                                                                                is-adecreased gamma-delta T cell number +
                                                                                is-adecreased memory T cell number +
                                                                                is-adecreased NK T cell number +
                                                                                is-adecreased regulatory T cell number +
                                                                                is-adecreased single-positive T cell number
                                                                                is-adecreased thymocyte number +


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal blood cell morphology/development
                                is-aabnormal hematopoiesis
                                        is-aabnormal hematopoietic cell number
                                                is-adecreased hematopoietic cell number
                                                        is-adecreased leukocyte cell number
                                                                is-adecreased lymphocyte cell number
                                                                        is-adecreased T cell number
                                                                                is-aabsent T cells +
                                                                                is-adecreased activated T cell number
                                                                                is-adecreased alpha-beta T cell number +
                                                                                is-adecreased double-negative T cell number +
                                                                                is-adecreased double-positive T cell number [MP:0005092] (317 genotypes, 317 annotations)
                                                                                is-adecreased gamma-delta T cell number +
                                                                                is-adecreased memory T cell number +
                                                                                is-adecreased NK T cell number +
                                                                                is-adecreased regulatory T cell number +
                                                                                is-adecreased single-positive T cell number
                                                                                is-adecreased thymocyte number +


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal blood cell morphology/development
                                is-aabnormal hematopoiesis
                                        is-aabnormal leukocyte morphology
                                                is-aabnormal leukocyte cell number
                                                        is-aabnormal lymphocyte cell number
                                                                is-aabnormal T cell number
                                                                        is-adecreased T cell number
                                                                                is-aabsent T cells +
                                                                                is-adecreased activated T cell number
                                                                                is-adecreased alpha-beta T cell number +
                                                                                is-adecreased double-negative T cell number +
                                                                                is-adecreased double-positive T cell number [MP:0005092] (317 genotypes, 317 annotations)
                                                                                is-adecreased gamma-delta T cell number +
                                                                                is-adecreased memory T cell number +
                                                                                is-adecreased NK T cell number +
                                                                                is-adecreased regulatory T cell number +
                                                                                is-adecreased single-positive T cell number
                                                                                is-adecreased thymocyte number +


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal blood cell morphology/development
                                is-aabnormal hematopoiesis
                                        is-aabnormal leukocyte morphology
                                                is-aabnormal leukocyte cell number
                                                        is-aabnormal lymphocyte cell number
                                                                is-adecreased lymphocyte cell number
                                                                        is-adecreased T cell number
                                                                                is-aabsent T cells +
                                                                                is-adecreased activated T cell number
                                                                                is-adecreased alpha-beta T cell number +
                                                                                is-adecreased double-negative T cell number +
                                                                                is-adecreased double-positive T cell number [MP:0005092] (317 genotypes, 317 annotations)
                                                                                is-adecreased gamma-delta T cell number +
                                                                                is-adecreased memory T cell number +
                                                                                is-adecreased NK T cell number +
                                                                                is-adecreased regulatory T cell number +
                                                                                is-adecreased single-positive T cell number
                                                                                is-adecreased thymocyte number +


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal blood cell morphology/development
                                is-aabnormal hematopoiesis
                                        is-aabnormal leukocyte morphology
                                                is-aabnormal leukocyte cell number
                                                        is-adecreased leukocyte cell number
                                                                is-adecreased lymphocyte cell number
                                                                        is-adecreased T cell number
                                                                                is-aabsent T cells +
                                                                                is-adecreased activated T cell number
                                                                                is-adecreased alpha-beta T cell number +
                                                                                is-adecreased double-negative T cell number +
                                                                                is-adecreased double-positive T cell number [MP:0005092] (317 genotypes, 317 annotations)
                                                                                is-adecreased gamma-delta T cell number +
                                                                                is-adecreased memory T cell number +
                                                                                is-adecreased NK T cell number +
                                                                                is-adecreased regulatory T cell number +
                                                                                is-adecreased single-positive T cell number
                                                                                is-adecreased thymocyte number +


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal blood cell morphology/development
                                is-aabnormal hematopoiesis
                                        is-aabnormal leukocyte morphology
                                                is-aabnormal mononuclear cell morphology
                                                        is-aabnormal lymphocyte morphology
                                                                is-aabnormal lymphocyte cell number
                                                                        is-aabnormal T cell number
                                                                                is-adecreased T cell number
                                                                                        is-aabsent T cells +
                                                                                        is-adecreased activated T cell number
                                                                                        is-adecreased alpha-beta T cell number +
                                                                                        is-adecreased double-negative T cell number +
                                                                                        is-adecreased double-positive T cell number [MP:0005092] (317 genotypes, 317 annotations)
                                                                                        is-adecreased gamma-delta T cell number +
                                                                                        is-adecreased memory T cell number +
                                                                                        is-adecreased NK T cell number +
                                                                                        is-adecreased regulatory T cell number +
                                                                                        is-adecreased single-positive T cell number
                                                                                        is-adecreased thymocyte number +


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal blood cell morphology/development
                                is-aabnormal hematopoiesis
                                        is-aabnormal leukocyte morphology
                                                is-aabnormal mononuclear cell morphology
                                                        is-aabnormal lymphocyte morphology
                                                                is-aabnormal lymphocyte cell number
                                                                        is-adecreased lymphocyte cell number
                                                                                is-adecreased T cell number
                                                                                        is-aabsent T cells +
                                                                                        is-adecreased activated T cell number
                                                                                        is-adecreased alpha-beta T cell number +
                                                                                        is-adecreased double-negative T cell number +
                                                                                        is-adecreased double-positive T cell number [MP:0005092] (317 genotypes, 317 annotations)
                                                                                        is-adecreased gamma-delta T cell number +
                                                                                        is-adecreased memory T cell number +
                                                                                        is-adecreased NK T cell number +
                                                                                        is-adecreased regulatory T cell number +
                                                                                        is-adecreased single-positive T cell number
                                                                                        is-adecreased thymocyte number +


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal blood cell morphology/development
                                is-aabnormal hematopoiesis
                                        is-aabnormal leukocyte morphology
                                                is-aabnormal mononuclear cell morphology
                                                        is-aabnormal lymphocyte morphology
                                                                is-aabnormal lymphopoiesis
                                                                        is-aabnormal T cell differentiation
                                                                                is-aabnormal double-positive T cell morphology
                                                                                        is-adecreased double-positive T cell number [MP:0005092] (317 genotypes, 317 annotations)
                                                                                        is-aincreased double-positive T cell number


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal blood cell morphology/development
                                is-aabnormal hematopoiesis
                                        is-aabnormal leukocyte morphology
                                                is-aabnormal mononuclear cell morphology
                                                        is-aabnormal lymphocyte morphology
                                                                is-aabnormal T cell morphology
                                                                        is-aabnormal T cell differentiation
                                                                                is-aabnormal double-positive T cell morphology
                                                                                        is-adecreased double-positive T cell number [MP:0005092] (317 genotypes, 317 annotations)
                                                                                        is-aincreased double-positive T cell number


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal blood cell morphology/development
                                is-aabnormal hematopoiesis
                                        is-aabnormal leukocyte morphology
                                                is-aabnormal mononuclear cell morphology
                                                        is-aabnormal lymphocyte morphology
                                                                is-aabnormal T cell morphology
                                                                        is-aabnormal T cell number
                                                                                is-adecreased T cell number
                                                                                        is-aabsent T cells +
                                                                                        is-adecreased activated T cell number
                                                                                        is-adecreased alpha-beta T cell number +
                                                                                        is-adecreased double-negative T cell number +
                                                                                        is-adecreased double-positive T cell number [MP:0005092] (317 genotypes, 317 annotations)
                                                                                        is-adecreased gamma-delta T cell number +
                                                                                        is-adecreased memory T cell number +
                                                                                        is-adecreased NK T cell number +
                                                                                        is-adecreased regulatory T cell number +
                                                                                        is-adecreased single-positive T cell number
                                                                                        is-adecreased thymocyte number +


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal blood cell morphology/development
                                is-aabnormal hematopoiesis
                                        is-aabnormal leukopoiesis
                                                is-aabnormal lymphopoiesis
                                                        is-aabnormal T cell differentiation
                                                                is-aabnormal double-positive T cell morphology
                                                                        is-adecreased double-positive T cell number [MP:0005092] (317 genotypes, 317 annotations)
                                                                        is-aincreased double-positive T cell number


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal leukocyte cell number
                                                is-aabnormal lymphocyte cell number
                                                        is-aabnormal T cell number
                                                                is-adecreased T cell number
                                                                        is-aabsent T cells +
                                                                        is-adecreased activated T cell number
                                                                        is-adecreased alpha-beta T cell number +
                                                                        is-adecreased double-negative T cell number +
                                                                        is-adecreased double-positive T cell number [MP:0005092] (317 genotypes, 317 annotations)
                                                                        is-adecreased gamma-delta T cell number +
                                                                        is-adecreased memory T cell number +
                                                                        is-adecreased NK T cell number +
                                                                        is-adecreased regulatory T cell number +
                                                                        is-adecreased single-positive T cell number
                                                                        is-adecreased thymocyte number +


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal leukocyte cell number
                                                is-aabnormal lymphocyte cell number
                                                        is-adecreased lymphocyte cell number
                                                                is-adecreased T cell number
                                                                        is-aabsent T cells +
                                                                        is-adecreased activated T cell number
                                                                        is-adecreased alpha-beta T cell number +
                                                                        is-adecreased double-negative T cell number +
                                                                        is-adecreased double-positive T cell number [MP:0005092] (317 genotypes, 317 annotations)
                                                                        is-adecreased gamma-delta T cell number +
                                                                        is-adecreased memory T cell number +
                                                                        is-adecreased NK T cell number +
                                                                        is-adecreased regulatory T cell number +
                                                                        is-adecreased single-positive T cell number
                                                                        is-adecreased thymocyte number +


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal leukocyte cell number
                                                is-adecreased leukocyte cell number
                                                        is-adecreased lymphocyte cell number
                                                                is-adecreased T cell number
                                                                        is-aabsent T cells +
                                                                        is-adecreased activated T cell number
                                                                        is-adecreased alpha-beta T cell number +
                                                                        is-adecreased double-negative T cell number +
                                                                        is-adecreased double-positive T cell number [MP:0005092] (317 genotypes, 317 annotations)
                                                                        is-adecreased gamma-delta T cell number +
                                                                        is-adecreased memory T cell number +
                                                                        is-adecreased NK T cell number +
                                                                        is-adecreased regulatory T cell number +
                                                                        is-adecreased single-positive T cell number
                                                                        is-adecreased thymocyte number +


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal mononuclear cell morphology
                                                is-aabnormal lymphocyte morphology
                                                        is-aabnormal lymphocyte cell number
                                                                is-aabnormal T cell number
                                                                        is-adecreased T cell number
                                                                                is-aabsent T cells +
                                                                                is-adecreased activated T cell number
                                                                                is-adecreased alpha-beta T cell number +
                                                                                is-adecreased double-negative T cell number +
                                                                                is-adecreased double-positive T cell number [MP:0005092] (317 genotypes, 317 annotations)
                                                                                is-adecreased gamma-delta T cell number +
                                                                                is-adecreased memory T cell number +
                                                                                is-adecreased NK T cell number +
                                                                                is-adecreased regulatory T cell number +
                                                                                is-adecreased single-positive T cell number
                                                                                is-adecreased thymocyte number +


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal mononuclear cell morphology
                                                is-aabnormal lymphocyte morphology
                                                        is-aabnormal lymphocyte cell number
                                                                is-adecreased lymphocyte cell number
                                                                        is-adecreased T cell number
                                                                                is-aabsent T cells +
                                                                                is-adecreased activated T cell number
                                                                                is-adecreased alpha-beta T cell number +
                                                                                is-adecreased double-negative T cell number +
                                                                                is-adecreased double-positive T cell number [MP:0005092] (317 genotypes, 317 annotations)
                                                                                is-adecreased gamma-delta T cell number +
                                                                                is-adecreased memory T cell number +
                                                                                is-adecreased NK T cell number +
                                                                                is-adecreased regulatory T cell number +
                                                                                is-adecreased single-positive T cell number
                                                                                is-adecreased thymocyte number +


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal mononuclear cell morphology
                                                is-aabnormal lymphocyte morphology
                                                        is-aabnormal lymphopoiesis
                                                                is-aabnormal T cell differentiation
                                                                        is-aabnormal double-positive T cell morphology
                                                                                is-adecreased double-positive T cell number [MP:0005092] (317 genotypes, 317 annotations)
                                                                                is-aincreased double-positive T cell number


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal mononuclear cell morphology
                                                is-aabnormal lymphocyte morphology
                                                        is-aabnormal T cell morphology
                                                                is-aabnormal T cell differentiation
                                                                        is-aabnormal double-positive T cell morphology
                                                                                is-adecreased double-positive T cell number [MP:0005092] (317 genotypes, 317 annotations)
                                                                                is-aincreased double-positive T cell number


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal mononuclear cell morphology
                                                is-aabnormal lymphocyte morphology
                                                        is-aabnormal T cell morphology
                                                                is-aabnormal T cell number
                                                                        is-adecreased T cell number
                                                                                is-aabsent T cells +
                                                                                is-adecreased activated T cell number
                                                                                is-adecreased alpha-beta T cell number +
                                                                                is-adecreased double-negative T cell number +
                                                                                is-adecreased double-positive T cell number [MP:0005092] (317 genotypes, 317 annotations)
                                                                                is-adecreased gamma-delta T cell number +
                                                                                is-adecreased memory T cell number +
                                                                                is-adecreased NK T cell number +
                                                                                is-adecreased regulatory T cell number +
                                                                                is-adecreased single-positive T cell number
                                                                                is-adecreased thymocyte number +


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal leukopoiesis
                                        is-aabnormal lymphopoiesis
                                                is-aabnormal T cell differentiation
                                                        is-aabnormal double-positive T cell morphology
                                                                is-adecreased double-positive T cell number [MP:0005092] (317 genotypes, 317 annotations)
                                                                is-aincreased double-positive T cell number

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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory