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Mammalian Phenotype Browser
Term Detail
MP term:defective cytotoxic T cell cytolysis
Synonym: defective CTL cytolysis
Synonym: defective cytotoxic T-cell cytolysis
Synonym: defective cytotoxic T lymphocyte cytolysis
MP id: MP:0005079
Definition: impaired ability of cytotoxic T cells to induce pathological breakdown of target cells by the destruction of their outer membrane
Number of paths to term: 4

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system physiology
                        is-aabnormal blood cell physiology
                                is-aabnormal leukocyte physiology
                                        is-aabnormal lymphocyte physiology
                                                is-aabnormal T cell physiology
                                                        is-aabnormal CD8-positive T cell physiology
                                                                is-aabnormal cytotoxic T cell physiology
                                                                        is-adecreased cytotoxic T cell apoptosis
                                                                        is-adefective cytotoxic T cell cytolysis [MP:0005079] (63 genotypes, 63 annotations)
                                                                        is-aincreased cytotoxic T cell apoptosis


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system physiology
                        is-aabnormal adaptive immunity
                                is-aabnormal leukocyte physiology
                                        is-aabnormal lymphocyte physiology
                                                is-aabnormal T cell physiology
                                                        is-aabnormal CD8-positive T cell physiology
                                                                is-aabnormal cytotoxic T cell physiology
                                                                        is-adecreased cytotoxic T cell apoptosis
                                                                        is-adefective cytotoxic T cell cytolysis [MP:0005079] (63 genotypes, 63 annotations)
                                                                        is-aincreased cytotoxic T cell apoptosis


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system physiology
                        is-aabnormal cell-mediated immunity
                                is-aabnormal leukocyte physiology
                                        is-aabnormal lymphocyte physiology
                                                is-aabnormal T cell physiology
                                                        is-aabnormal CD8-positive T cell physiology
                                                                is-aabnormal cytotoxic T cell physiology
                                                                        is-adecreased cytotoxic T cell apoptosis
                                                                        is-adefective cytotoxic T cell cytolysis [MP:0005079] (63 genotypes, 63 annotations)
                                                                        is-aincreased cytotoxic T cell apoptosis


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system physiology
                        is-aabnormal immune cell physiology
                                is-aabnormal leukocyte physiology
                                        is-aabnormal lymphocyte physiology
                                                is-aabnormal T cell physiology
                                                        is-aabnormal CD8-positive T cell physiology
                                                                is-aabnormal cytotoxic T cell physiology
                                                                        is-adecreased cytotoxic T cell apoptosis
                                                                        is-adefective cytotoxic T cell cytolysis [MP:0005079] (63 genotypes, 63 annotations)
                                                                        is-aincreased cytotoxic T cell apoptosis

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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory