About   Help   FAQ
Mammalian Phenotype Browser
Term Detail
MP term:abnormal cytotoxic T cell physiology
Synonym: CTL dysfunction
Synonym: cytotoxic T cell dysfunction
Synonym: cytotoxic T-cell dysfunction
Synonym: cytotoxic T lymphocyte dysfunction
MP id: MP:0005078
Definition: any functional anomaly of the subset of CD8-positive T lymphocytes capable of directly killing appropriately targeted cells
Number of paths to term: 4

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system physiology
                        is-aabnormal blood cell physiology
                                is-aabnormal leukocyte physiology
                                        is-aabnormal lymphocyte physiology
                                                is-aabnormal T cell physiology
                                                        is-aabnormal CD8-positive, alpha-beta T cell physiology
                                                                is-aabnormal cytotoxic T cell physiology [MP:0005078] (135 genotypes, 145 annotations)
                                                                        is-aabnormal cytotoxic T cell cytolysis +
                                                                        is-adecreased cytotoxic T cell apoptosis
                                                                        is-aincreased cytotoxic T cell apoptosis


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system physiology
                        is-aabnormal adaptive immunity
                                is-aabnormal leukocyte physiology
                                        is-aabnormal lymphocyte physiology
                                                is-aabnormal T cell physiology
                                                        is-aabnormal CD8-positive, alpha-beta T cell physiology
                                                                is-aabnormal cytotoxic T cell physiology [MP:0005078] (135 genotypes, 145 annotations)
                                                                        is-aabnormal cytotoxic T cell cytolysis +
                                                                        is-adecreased cytotoxic T cell apoptosis
                                                                        is-aincreased cytotoxic T cell apoptosis


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system physiology
                        is-aabnormal cell-mediated immunity
                                is-aabnormal leukocyte physiology
                                        is-aabnormal lymphocyte physiology
                                                is-aabnormal T cell physiology
                                                        is-aabnormal CD8-positive, alpha-beta T cell physiology
                                                                is-aabnormal cytotoxic T cell physiology [MP:0005078] (135 genotypes, 145 annotations)
                                                                        is-aabnormal cytotoxic T cell cytolysis +
                                                                        is-adecreased cytotoxic T cell apoptosis
                                                                        is-aincreased cytotoxic T cell apoptosis


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system physiology
                        is-aabnormal immune cell physiology
                                is-aabnormal leukocyte physiology
                                        is-aabnormal lymphocyte physiology
                                                is-aabnormal T cell physiology
                                                        is-aabnormal CD8-positive, alpha-beta T cell physiology
                                                                is-aabnormal cytotoxic T cell physiology [MP:0005078] (135 genotypes, 145 annotations)
                                                                        is-aabnormal cytotoxic T cell cytolysis +
                                                                        is-adecreased cytotoxic T cell apoptosis
                                                                        is-aincreased cytotoxic T cell apoptosis

Back to entry page

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
09/09/2014
MGI 5.19
The Jackson Laboratory