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Term Detail
MP term:abnormal cytotoxic T cell physiology
Synonym: CTL dysfunction
Synonym: cytotoxic T cell dysfunction
Synonym: cytotoxic T-cell dysfunction
Synonym: cytotoxic T lymphocyte dysfunction
MP id: MP:0005078
Definition: any functional anomaly of the subset of CD8-positive T lymphocytes capable of directly killing appropriately targeted cells
Number of paths to term: 3

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system physiology
                        is-aabnormal adaptive immunity
                                is-aabnormal leukocyte physiology
                                        is-aabnormal lymphocyte physiology
                                                is-aabnormal T cell physiology
                                                        is-aabnormal CD8-positive T cell physiology
                                                                is-aabnormal cytotoxic T cell physiology [MP:0005078] (133 genotypes, 143 annotations)
                                                                        is-adefective cytotoxic T cell cytolysis


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system physiology
                        is-aabnormal cell-mediated immunity
                                is-aabnormal leukocyte physiology
                                        is-aabnormal lymphocyte physiology
                                                is-aabnormal T cell physiology
                                                        is-aabnormal CD8-positive T cell physiology
                                                                is-aabnormal cytotoxic T cell physiology [MP:0005078] (133 genotypes, 143 annotations)
                                                                        is-adefective cytotoxic T cell cytolysis


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system physiology
                        is-aabnormal immune cell physiology
                                is-aabnormal leukocyte physiology
                                        is-aabnormal lymphocyte physiology
                                                is-aabnormal T cell physiology
                                                        is-aabnormal CD8-positive T cell physiology
                                                                is-aabnormal cytotoxic T cell physiology [MP:0005078] (133 genotypes, 143 annotations)
                                                                        is-adefective cytotoxic T cell cytolysis

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last database update
05/08/2013
MGI 5.13
The Jackson Laboratory