| MP term: | impaired natural killer cell mediated cytotoxicity |
| Synonym: | defective natural killer cell cytolysis |
| Synonym: | defective NK cell cytolysis |
| Synonym: | impaired killer activity |
| Synonym: | impaired natural killer cell mediated cell death |
| Synonym: | impaired natural killer cell mediated cell killing |
| Synonym: | impaired natural killer cell mediated cytolysis |
| Synonym: | impaired natural killer-cell mediated cytolysis |
| Synonym: | impaired NK cell cytolysis |
| Synonym: | impaired NK cell mediated cell death |
| Synonym: | impaired NK cell mediated cell killing |
| Synonym: | impaired NK cell mediated cytolysis |
| Synonym: | impaired NK cell mediated cytotoxicity |
| MP id: | MP:0005070 |
| Definition: | impaired ability of directed killing of a target cell by a natural killer cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors |
| Number of paths to term: | 4 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
immune system phenotypeabnormal immune system physiologyabnormal adaptive immunityabnormal leukocyte physiologyabnormal lymphocyte physiologyabnormal NK cell physiologyabnormal natural killer cell mediated cytotoxicityabnormal NK cell degranulation +impaired natural killer cell mediated cytotoxicity [MP:0005070] (91 genotypes, 91 annotations)increased natural killer cell mediated cytotoxicityimmune system phenotypeabnormal immune system physiologyabnormal cell-mediated immunityabnormal leukocyte physiologyabnormal lymphocyte physiologyabnormal NK cell physiologyabnormal natural killer cell mediated cytotoxicityabnormal NK cell degranulation +impaired natural killer cell mediated cytotoxicity [MP:0005070] (91 genotypes, 91 annotations)increased natural killer cell mediated cytotoxicityimmune system phenotypeabnormal immune system physiologyabnormal immune cell physiologyabnormal leukocyte physiologyabnormal lymphocyte physiologyabnormal NK cell physiologyabnormal natural killer cell mediated cytotoxicityabnormal NK cell degranulation +impaired natural killer cell mediated cytotoxicity [MP:0005070] (91 genotypes, 91 annotations)increased natural killer cell mediated cytotoxicityimmune system phenotypeabnormal immune system physiologyabnormal innate immunityabnormal NK cell physiologyabnormal natural killer cell mediated cytotoxicityabnormal NK cell degranulation +impaired natural killer cell mediated cytotoxicity [MP:0005070] (91 genotypes, 91 annotations)increased natural killer cell mediated cytotoxicityMouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/22/2013 MGI 5.13 |
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