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Mammalian Phenotype Browser
Term Detail
MP term:impaired natural killer cell mediated cytotoxicity
Synonym: defective natural killer cell cytolysis
Synonym: defective NK cell cytolysis
Synonym: impaired killer activity
Synonym: impaired natural killer cell mediated cell death
Synonym: impaired natural killer cell mediated cell killing
Synonym: impaired natural killer cell mediated cytolysis
Synonym: impaired natural killer-cell mediated cytolysis
Synonym: impaired NK cell cytolysis
Synonym: impaired NK cell mediated cell death
Synonym: impaired NK cell mediated cell killing
Synonym: impaired NK cell mediated cytolysis
Synonym: impaired NK cell mediated cytotoxicity
MP id: MP:0005070
Definition: impaired ability of directed killing of a target cell by a natural killer cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors
Number of paths to term: 5

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system physiology
                        is-aabnormal blood cell physiology
                                is-aabnormal leukocyte physiology
                                        is-aabnormal lymphocyte physiology
                                                is-aabnormal NK cell physiology
                                                        is-aabnormal natural killer cell mediated cytotoxicity
                                                                is-aabnormal NK cell degranulation +
                                                                is-aimpaired natural killer cell mediated cytotoxicity [MP:0005070] (97 genotypes, 97 annotations)
                                                                is-aincreased natural killer cell mediated cytotoxicity


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system physiology
                        is-aabnormal adaptive immunity
                                is-aabnormal leukocyte physiology
                                        is-aabnormal lymphocyte physiology
                                                is-aabnormal NK cell physiology
                                                        is-aabnormal natural killer cell mediated cytotoxicity
                                                                is-aabnormal NK cell degranulation +
                                                                is-aimpaired natural killer cell mediated cytotoxicity [MP:0005070] (97 genotypes, 97 annotations)
                                                                is-aincreased natural killer cell mediated cytotoxicity


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system physiology
                        is-aabnormal cell-mediated immunity
                                is-aabnormal leukocyte physiology
                                        is-aabnormal lymphocyte physiology
                                                is-aabnormal NK cell physiology
                                                        is-aabnormal natural killer cell mediated cytotoxicity
                                                                is-aabnormal NK cell degranulation +
                                                                is-aimpaired natural killer cell mediated cytotoxicity [MP:0005070] (97 genotypes, 97 annotations)
                                                                is-aincreased natural killer cell mediated cytotoxicity


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system physiology
                        is-aabnormal immune cell physiology
                                is-aabnormal leukocyte physiology
                                        is-aabnormal lymphocyte physiology
                                                is-aabnormal NK cell physiology
                                                        is-aabnormal natural killer cell mediated cytotoxicity
                                                                is-aabnormal NK cell degranulation +
                                                                is-aimpaired natural killer cell mediated cytotoxicity [MP:0005070] (97 genotypes, 97 annotations)
                                                                is-aincreased natural killer cell mediated cytotoxicity


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system physiology
                        is-aabnormal innate immunity
                                is-aabnormal NK cell physiology
                                        is-aabnormal natural killer cell mediated cytotoxicity
                                                is-aabnormal NK cell degranulation +
                                                is-aimpaired natural killer cell mediated cytotoxicity [MP:0005070] (97 genotypes, 97 annotations)
                                                is-aincreased natural killer cell mediated cytotoxicity

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last database update
08/26/2014
MGI 5.19
The Jackson Laboratory