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Term Detail
MP term:abnormal level of surface class II molecules
MP id: MP:0005042
Definition: deviation from the normal concentration of major histocompatibility complex class II molecules expressed at the cell surface
Number of paths to term: 9

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system physiology
                        is-aabnormal blood cell physiology
                                is-aabnormal leukocyte physiology
                                        is-aabnormal lymphocyte physiology
                                                is-aabnormal B cell physiology
                                                        is-aabnormal B lymphocyte antigen presentation
                                                                is-aabnormal antigen presentation via MHC class II
                                                                        is-aabnormal level of surface class II molecules [MP:0005042] (38 genotypes, 41 annotations)
                                                                                is-aabnormal MHC II cell surface expression on macrophages
                                                                                is-adecreased level of surface class II molecules
                                                                                is-aincreased level of surface class II molecules
                                                                        is-adefective assembly of class II molecules


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system physiology
                        is-aabnormal adaptive immunity
                                is-aabnormal leukocyte physiology
                                        is-aabnormal lymphocyte physiology
                                                is-aabnormal B cell physiology
                                                        is-aabnormal B lymphocyte antigen presentation
                                                                is-aabnormal antigen presentation via MHC class II
                                                                        is-aabnormal level of surface class II molecules [MP:0005042] (38 genotypes, 41 annotations)
                                                                                is-aabnormal MHC II cell surface expression on macrophages
                                                                                is-adecreased level of surface class II molecules
                                                                                is-aincreased level of surface class II molecules
                                                                        is-adefective assembly of class II molecules


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system physiology
                        is-aabnormal adaptive immunity
                                is-aabnormal professional antigen presenting cell physiology
                                        is-aabnormal B cell physiology
                                                is-aabnormal B lymphocyte antigen presentation
                                                        is-aabnormal antigen presentation via MHC class II
                                                                is-aabnormal level of surface class II molecules [MP:0005042] (38 genotypes, 41 annotations)
                                                                        is-aabnormal MHC II cell surface expression on macrophages
                                                                        is-adecreased level of surface class II molecules
                                                                        is-aincreased level of surface class II molecules
                                                                is-adefective assembly of class II molecules


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system physiology
                        is-aabnormal antigen presentation
                                is-aabnormal antigen presentation via MHC class II
                                        is-aabnormal level of surface class II molecules [MP:0005042] (38 genotypes, 41 annotations)
                                                is-aabnormal MHC II cell surface expression on macrophages
                                                is-adecreased level of surface class II molecules
                                                is-aincreased level of surface class II molecules
                                        is-adefective assembly of class II molecules


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system physiology
                        is-aabnormal antigen presentation
                                is-aabnormal B lymphocyte antigen presentation
                                        is-aabnormal antigen presentation via MHC class II
                                                is-aabnormal level of surface class II molecules [MP:0005042] (38 genotypes, 41 annotations)
                                                        is-aabnormal MHC II cell surface expression on macrophages
                                                        is-adecreased level of surface class II molecules
                                                        is-aincreased level of surface class II molecules
                                                is-adefective assembly of class II molecules


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system physiology
                        is-aabnormal cell-mediated immunity
                                is-aabnormal leukocyte physiology
                                        is-aabnormal lymphocyte physiology
                                                is-aabnormal B cell physiology
                                                        is-aabnormal B lymphocyte antigen presentation
                                                                is-aabnormal antigen presentation via MHC class II
                                                                        is-aabnormal level of surface class II molecules [MP:0005042] (38 genotypes, 41 annotations)
                                                                                is-aabnormal MHC II cell surface expression on macrophages
                                                                                is-adecreased level of surface class II molecules
                                                                                is-aincreased level of surface class II molecules
                                                                        is-adefective assembly of class II molecules


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system physiology
                        is-aabnormal cell-mediated immunity
                                is-aabnormal professional antigen presenting cell physiology
                                        is-aabnormal B cell physiology
                                                is-aabnormal B lymphocyte antigen presentation
                                                        is-aabnormal antigen presentation via MHC class II
                                                                is-aabnormal level of surface class II molecules [MP:0005042] (38 genotypes, 41 annotations)
                                                                        is-aabnormal MHC II cell surface expression on macrophages
                                                                        is-adecreased level of surface class II molecules
                                                                        is-aincreased level of surface class II molecules
                                                                is-adefective assembly of class II molecules


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system physiology
                        is-aabnormal immune cell physiology
                                is-aabnormal leukocyte physiology
                                        is-aabnormal lymphocyte physiology
                                                is-aabnormal B cell physiology
                                                        is-aabnormal B lymphocyte antigen presentation
                                                                is-aabnormal antigen presentation via MHC class II
                                                                        is-aabnormal level of surface class II molecules [MP:0005042] (38 genotypes, 41 annotations)
                                                                                is-aabnormal MHC II cell surface expression on macrophages
                                                                                is-adecreased level of surface class II molecules
                                                                                is-aincreased level of surface class II molecules
                                                                        is-adefective assembly of class II molecules


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system physiology
                        is-aabnormal immune cell physiology
                                is-aabnormal professional antigen presenting cell physiology
                                        is-aabnormal B cell physiology
                                                is-aabnormal B lymphocyte antigen presentation
                                                        is-aabnormal antigen presentation via MHC class II
                                                                is-aabnormal level of surface class II molecules [MP:0005042] (38 genotypes, 41 annotations)
                                                                        is-aabnormal MHC II cell surface expression on macrophages
                                                                        is-adecreased level of surface class II molecules
                                                                        is-aincreased level of surface class II molecules
                                                                is-adefective assembly of class II molecules

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory