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Mammalian Phenotype Browser
Term Detail
MP term:abnormal immature B cell morphology
Synonym: immature B cell abnormalities
Synonym: immature B-cell abnormalities
Synonym: immature B lymphocyte abnormalities
MP id: MP:0005022
Definition: any structural anomaly of the cells of the B lymphocyte lineage that have undergone VDJ rearrangement of the heavy chain and V-J rearrangement of the light chain; these cells express IgM on the cell surface but have not yet been selected for self-reactivity
Number of paths to term: 8

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal blood cell morphology/development
                                is-aabnormal hematopoiesis
                                        is-aabnormal leukocyte morphology
                                                is-aabnormal mononuclear cell morphology
                                                        is-aabnormal lymphocyte morphology
                                                                is-aabnormal B cell morphology
                                                                        is-aabnormal B cell differentiation
                                                                                is-aabnormal B cell activation +
                                                                                is-aabnormal B cell receptor editing
                                                                                is-aabnormal B cell selection +
                                                                                is-aabnormal class switch recombination
                                                                                is-aabnormal immature B cell morphology [MP:0005022] (415 genotypes, 589 annotations)
                                                                                        is-aabnormal pre-B cell morphology +
                                                                                        is-aabnormal transitional stage B cell morphology +
                                                                                        is-adecreased immature B cell number +
                                                                                        is-aincreased immature B cell number +
                                                                                is-aabnormal immunoglobulin V(D)J recombination +
                                                                                is-aabnormal memory B cell differentiation
                                                                                is-aabnormal plasma cell differentiation
                                                                                is-aabnormal pro-B cell morphology +
                                                                                is-aabnormal somatic hypermutation frequency
                                                                                is-aarrested B cell differentiation


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal blood cell morphology/development
                                is-aabnormal hematopoiesis
                                        is-aabnormal leukocyte morphology
                                                is-aabnormal mononuclear cell morphology
                                                        is-aabnormal lymphocyte morphology
                                                                is-aabnormal B cell morphology
                                                                        is-aabnormal B cell differentiation +
                                                                        is-aabnormal B cell number +
                                                                        is-aabnormal immature B cell morphology [MP:0005022] (415 genotypes, 589 annotations)
                                                                                is-aabnormal pre-B cell morphology +
                                                                                is-aabnormal transitional stage B cell morphology +
                                                                                is-adecreased immature B cell number +
                                                                                is-aincreased immature B cell number +
                                                                        is-aabnormal mature B cell morphology +
                                                                        is-aabnormal plasma cell morphology +


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal blood cell morphology/development
                                is-aabnormal hematopoiesis
                                        is-aabnormal leukocyte morphology
                                                is-aabnormal mononuclear cell morphology
                                                        is-aabnormal lymphocyte morphology
                                                                is-aabnormal lymphopoiesis
                                                                        is-aabnormal B cell differentiation
                                                                                is-aabnormal B cell activation +
                                                                                is-aabnormal B cell receptor editing
                                                                                is-aabnormal B cell selection +
                                                                                is-aabnormal class switch recombination
                                                                                is-aabnormal immature B cell morphology [MP:0005022] (415 genotypes, 589 annotations)
                                                                                        is-aabnormal pre-B cell morphology +
                                                                                        is-aabnormal transitional stage B cell morphology +
                                                                                        is-adecreased immature B cell number +
                                                                                        is-aincreased immature B cell number +
                                                                                is-aabnormal immunoglobulin V(D)J recombination +
                                                                                is-aabnormal memory B cell differentiation
                                                                                is-aabnormal plasma cell differentiation
                                                                                is-aabnormal pro-B cell morphology +
                                                                                is-aabnormal somatic hypermutation frequency
                                                                                is-aarrested B cell differentiation


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal blood cell morphology/development
                                is-aabnormal hematopoiesis
                                        is-aabnormal leukopoiesis
                                                is-aabnormal lymphopoiesis
                                                        is-aabnormal B cell differentiation
                                                                is-aabnormal B cell activation +
                                                                is-aabnormal B cell receptor editing
                                                                is-aabnormal B cell selection +
                                                                is-aabnormal class switch recombination
                                                                is-aabnormal immature B cell morphology [MP:0005022] (415 genotypes, 589 annotations)
                                                                        is-aabnormal pre-B cell morphology +
                                                                        is-aabnormal transitional stage B cell morphology +
                                                                        is-adecreased immature B cell number +
                                                                        is-aincreased immature B cell number +
                                                                is-aabnormal immunoglobulin V(D)J recombination +
                                                                is-aabnormal memory B cell differentiation
                                                                is-aabnormal plasma cell differentiation
                                                                is-aabnormal pro-B cell morphology +
                                                                is-aabnormal somatic hypermutation frequency
                                                                is-aarrested B cell differentiation


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal mononuclear cell morphology
                                                is-aabnormal lymphocyte morphology
                                                        is-aabnormal B cell morphology
                                                                is-aabnormal B cell differentiation
                                                                        is-aabnormal B cell activation +
                                                                        is-aabnormal B cell receptor editing
                                                                        is-aabnormal B cell selection +
                                                                        is-aabnormal class switch recombination
                                                                        is-aabnormal immature B cell morphology [MP:0005022] (415 genotypes, 589 annotations)
                                                                                is-aabnormal pre-B cell morphology +
                                                                                is-aabnormal transitional stage B cell morphology +
                                                                                is-adecreased immature B cell number +
                                                                                is-aincreased immature B cell number +
                                                                        is-aabnormal immunoglobulin V(D)J recombination +
                                                                        is-aabnormal memory B cell differentiation
                                                                        is-aabnormal plasma cell differentiation
                                                                        is-aabnormal pro-B cell morphology +
                                                                        is-aabnormal somatic hypermutation frequency
                                                                        is-aarrested B cell differentiation


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal mononuclear cell morphology
                                                is-aabnormal lymphocyte morphology
                                                        is-aabnormal B cell morphology
                                                                is-aabnormal B cell differentiation +
                                                                is-aabnormal B cell number +
                                                                is-aabnormal immature B cell morphology [MP:0005022] (415 genotypes, 589 annotations)
                                                                        is-aabnormal pre-B cell morphology +
                                                                        is-aabnormal transitional stage B cell morphology +
                                                                        is-adecreased immature B cell number +
                                                                        is-aincreased immature B cell number +
                                                                is-aabnormal mature B cell morphology +
                                                                is-aabnormal plasma cell morphology +


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal mononuclear cell morphology
                                                is-aabnormal lymphocyte morphology
                                                        is-aabnormal lymphopoiesis
                                                                is-aabnormal B cell differentiation
                                                                        is-aabnormal B cell activation +
                                                                        is-aabnormal B cell receptor editing
                                                                        is-aabnormal B cell selection +
                                                                        is-aabnormal class switch recombination
                                                                        is-aabnormal immature B cell morphology [MP:0005022] (415 genotypes, 589 annotations)
                                                                                is-aabnormal pre-B cell morphology +
                                                                                is-aabnormal transitional stage B cell morphology +
                                                                                is-adecreased immature B cell number +
                                                                                is-aincreased immature B cell number +
                                                                        is-aabnormal immunoglobulin V(D)J recombination +
                                                                        is-aabnormal memory B cell differentiation
                                                                        is-aabnormal plasma cell differentiation
                                                                        is-aabnormal pro-B cell morphology +
                                                                        is-aabnormal somatic hypermutation frequency
                                                                        is-aarrested B cell differentiation


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal leukopoiesis
                                        is-aabnormal lymphopoiesis
                                                is-aabnormal B cell differentiation
                                                        is-aabnormal B cell activation +
                                                        is-aabnormal B cell receptor editing
                                                        is-aabnormal B cell selection +
                                                        is-aabnormal class switch recombination
                                                        is-aabnormal immature B cell morphology [MP:0005022] (415 genotypes, 589 annotations)
                                                                is-aabnormal pre-B cell morphology +
                                                                is-aabnormal transitional stage B cell morphology +
                                                                is-adecreased immature B cell number +
                                                                is-aincreased immature B cell number +
                                                        is-aabnormal immunoglobulin V(D)J recombination +
                                                        is-aabnormal memory B cell differentiation
                                                        is-aabnormal plasma cell differentiation
                                                        is-aabnormal pro-B cell morphology +
                                                        is-aabnormal somatic hypermutation frequency
                                                        is-aarrested B cell differentiation

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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory