| MP term: | abnormal immature B cell morphology |
| Synonym: | immature B cell abnormalities |
| Synonym: | immature B-cell abnormalities |
| Synonym: | immature B lymphocyte abnormalities |
| MP id: | MP:0005022 |
| Definition: | any structural anomaly of the cells of the B lymphocyte lineage that have undergone VDJ rearrangement of the heavy chain and V-J rearrangement of the light chain; these cells express IgM on the cell surface but have not yet been selected for self-reactivity |
| Number of paths to term: | 15 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
cellular phenotypeabnormal cell physiologyabnormal cell differentiationabnormal mononuclear cell differentiationabnormal lymphopoiesisabnormal B cell differentiationabnormal B cell activation +abnormal B cell receptor editingabnormal B cell selection +abnormal class switch recombinationabnormal immature B cell morphology [MP:0005022] (387 genotypes, 552 annotations)abnormal pre-B cell morphology +abnormal transitional stage B cell morphology +absent immature B cells +decreased immature B cell number +increased immature B cell number +abnormal immunoglobulin V(D)J recombination +abnormal memory B cell differentiationabnormal plasma cell differentiationabnormal pro-B cell morphology +abnormal somatic hypermutation frequencyarrested B cell differentiationhematopoietic system phenotypeabnormal hematopoietic system morphology/developmentabnormal blood cell morphology/developmentabnormal hematopoiesisabnormal leukocyte morphologyabnormal mononuclear cell morphologyabnormal lymphocyte morphologyabnormal B cell morphologyabnormal B cell differentiationabnormal B cell activation +abnormal B cell receptor editingabnormal B cell selection +abnormal class switch recombinationabnormal immature B cell morphology [MP:0005022] (387 genotypes, 552 annotations)abnormal pre-B cell morphology +abnormal transitional stage B cell morphology +absent immature B cells +decreased immature B cell number +increased immature B cell number +abnormal immunoglobulin V(D)J recombination +abnormal memory B cell differentiationabnormal plasma cell differentiationabnormal pro-B cell morphology +abnormal somatic hypermutation frequencyarrested B cell differentiationhematopoietic system phenotypeabnormal hematopoietic system morphology/developmentabnormal blood cell morphology/developmentabnormal hematopoiesisabnormal leukocyte morphologyabnormal mononuclear cell morphologyabnormal lymphocyte morphologyabnormal B cell morphologyabnormal B cell differentiation +abnormal B cell number +abnormal immature B cell morphology [MP:0005022] (387 genotypes, 552 annotations)abnormal pre-B cell morphology +abnormal transitional stage B cell morphology +absent immature B cells +decreased immature B cell number +increased immature B cell number +abnormal mature B cell morphology +abnormal plasma cell morphology +hematopoietic system phenotypeabnormal hematopoietic system morphology/developmentabnormal blood cell morphology/developmentabnormal hematopoiesisabnormal leukocyte morphologyabnormal mononuclear cell morphologyabnormal lymphocyte morphologyabnormal lymphopoiesisabnormal B cell differentiationabnormal B cell activation +abnormal B cell receptor editingabnormal B cell selection +abnormal class switch recombinationabnormal immature B cell morphology [MP:0005022] (387 genotypes, 552 annotations)abnormal pre-B cell morphology +abnormal transitional stage B cell morphology +absent immature B cells +decreased immature B cell number +increased immature B cell number +abnormal immunoglobulin V(D)J recombination +abnormal memory B cell differentiationabnormal plasma cell differentiationabnormal pro-B cell morphology +abnormal somatic hypermutation frequencyarrested B cell differentiationhematopoietic system phenotypeabnormal hematopoietic system morphology/developmentabnormal blood cell morphology/developmentabnormal hematopoiesisabnormal leukopoiesisabnormal lymphopoiesisabnormal B cell differentiationabnormal B cell activation +abnormal B cell receptor editingabnormal B cell selection +abnormal class switch recombinationabnormal immature B cell morphology [MP:0005022] (387 genotypes, 552 annotations)abnormal pre-B cell morphology +abnormal transitional stage B cell morphology +absent immature B cells +decreased immature B cell number +increased immature B cell number +abnormal immunoglobulin V(D)J recombination +abnormal memory B cell differentiationabnormal plasma cell differentiationabnormal pro-B cell morphology +abnormal somatic hypermutation frequencyarrested B cell differentiationhematopoietic system phenotypeabnormal hematopoietic system morphology/developmentabnormal blood cell morphology/developmentabnormal hematopoiesisabnormal leukopoiesisabnormal mononuclear cell differentiationabnormal lymphopoiesisabnormal B cell differentiationabnormal B cell activation +abnormal B cell receptor editingabnormal B cell selection +abnormal class switch recombinationabnormal immature B cell morphology [MP:0005022] (387 genotypes, 552 annotations)abnormal pre-B cell morphology +abnormal transitional stage B cell morphology +absent immature B cells +decreased immature B cell number +increased immature B cell number +abnormal immunoglobulin V(D)J recombination +abnormal memory B cell differentiationabnormal plasma cell differentiationabnormal pro-B cell morphology +abnormal somatic hypermutation frequencyarrested B cell differentiationhematopoietic system phenotypeabnormal hematopoietic system morphology/developmentabnormal blood cell morphology/developmentabnormal leukocyte morphologyabnormal mononuclear cell morphologyabnormal lymphocyte morphologyabnormal B cell morphologyabnormal B cell differentiationabnormal B cell activation +abnormal B cell receptor editingabnormal B cell selection +abnormal class switch recombinationabnormal immature B cell morphology [MP:0005022] (387 genotypes, 552 annotations)abnormal pre-B cell morphology +abnormal transitional stage B cell morphology +absent immature B cells +decreased immature B cell number +increased immature B cell number +abnormal immunoglobulin V(D)J recombination +abnormal memory B cell differentiationabnormal plasma cell differentiationabnormal pro-B cell morphology +abnormal somatic hypermutation frequencyarrested B cell differentiationhematopoietic system phenotypeabnormal hematopoietic system morphology/developmentabnormal blood cell morphology/developmentabnormal leukocyte morphologyabnormal mononuclear cell morphologyabnormal lymphocyte morphologyabnormal B cell morphologyabnormal B cell differentiation +abnormal B cell number +abnormal immature B cell morphology [MP:0005022] (387 genotypes, 552 annotations)abnormal pre-B cell morphology +abnormal transitional stage B cell morphology +absent immature B cells +decreased immature B cell number +increased immature B cell number +abnormal mature B cell morphology +abnormal plasma cell morphology +hematopoietic system phenotypeabnormal hematopoietic system morphology/developmentabnormal blood cell morphology/developmentabnormal leukocyte morphologyabnormal mononuclear cell morphologyabnormal lymphocyte morphologyabnormal lymphopoiesisabnormal B cell differentiationabnormal B cell activation +abnormal B cell receptor editingabnormal B cell selection +abnormal class switch recombinationabnormal immature B cell morphology [MP:0005022] (387 genotypes, 552 annotations)abnormal pre-B cell morphology +abnormal transitional stage B cell morphology +absent immature B cells +decreased immature B cell number +increased immature B cell number +abnormal immunoglobulin V(D)J recombination +abnormal memory B cell differentiationabnormal plasma cell differentiationabnormal pro-B cell morphology +abnormal somatic hypermutation frequencyarrested B cell differentiationhematopoietic system phenotypeabnormal hematopoietic system morphology/developmentabnormal bone marrow cell morphology/developmentabnormal myeloblast morphology/developmentabnormal mononuclear cell differentiationabnormal lymphopoiesisabnormal B cell differentiationabnormal B cell activation +abnormal B cell receptor editingabnormal B cell selection +abnormal class switch recombinationabnormal immature B cell morphology [MP:0005022] (387 genotypes, 552 annotations)abnormal pre-B cell morphology +abnormal transitional stage B cell morphology +absent immature B cells +decreased immature B cell number +increased immature B cell number +abnormal immunoglobulin V(D)J recombination +abnormal memory B cell differentiationabnormal plasma cell differentiationabnormal pro-B cell morphology +abnormal somatic hypermutation frequencyarrested B cell differentiationimmune system phenotypeabnormal immune system morphologyabnormal immune system cell morphologyabnormal leukocyte morphologyabnormal mononuclear cell morphologyabnormal lymphocyte morphologyabnormal B cell morphologyabnormal B cell differentiationabnormal B cell activation +abnormal B cell receptor editingabnormal B cell selection +abnormal class switch recombinationabnormal immature B cell morphology [MP:0005022] (387 genotypes, 552 annotations)abnormal pre-B cell morphology +abnormal transitional stage B cell morphology +absent immature B cells +decreased immature B cell number +increased immature B cell number +abnormal immunoglobulin V(D)J recombination +abnormal memory B cell differentiationabnormal plasma cell differentiationabnormal pro-B cell morphology +abnormal somatic hypermutation frequencyarrested B cell differentiationimmune system phenotypeabnormal immune system morphologyabnormal immune system cell morphologyabnormal leukocyte morphologyabnormal mononuclear cell morphologyabnormal lymphocyte morphologyabnormal B cell morphologyabnormal B cell differentiation +abnormal B cell number +abnormal immature B cell morphology [MP:0005022] (387 genotypes, 552 annotations)abnormal pre-B cell morphology +abnormal transitional stage B cell morphology +absent immature B cells +decreased immature B cell number +increased immature B cell number +abnormal mature B cell morphology +abnormal plasma cell morphology +immune system phenotypeabnormal immune system morphologyabnormal immune system cell morphologyabnormal leukocyte morphologyabnormal mononuclear cell morphologyabnormal lymphocyte morphologyabnormal lymphopoiesisabnormal B cell differentiationabnormal B cell activation +abnormal B cell receptor editingabnormal B cell selection +abnormal class switch recombinationabnormal immature B cell morphology [MP:0005022] (387 genotypes, 552 annotations)abnormal pre-B cell morphology +abnormal transitional stage B cell morphology +absent immature B cells +decreased immature B cell number +increased immature B cell number +abnormal immunoglobulin V(D)J recombination +abnormal memory B cell differentiationabnormal plasma cell differentiationabnormal pro-B cell morphology +abnormal somatic hypermutation frequencyarrested B cell differentiationimmune system phenotypeabnormal immune system morphologyabnormal immune system cell morphologyabnormal leukopoiesisabnormal lymphopoiesisabnormal B cell differentiationabnormal B cell activation +abnormal B cell receptor editingabnormal B cell selection +abnormal class switch recombinationabnormal immature B cell morphology [MP:0005022] (387 genotypes, 552 annotations)abnormal pre-B cell morphology +abnormal transitional stage B cell morphology +absent immature B cells +decreased immature B cell number +increased immature B cell number +abnormal immunoglobulin V(D)J recombination +abnormal memory B cell differentiationabnormal plasma cell differentiationabnormal pro-B cell morphology +abnormal somatic hypermutation frequencyarrested B cell differentiationimmune system phenotypeabnormal immune system morphologyabnormal immune system cell morphologyabnormal leukopoiesisabnormal mononuclear cell differentiationabnormal lymphopoiesisabnormal B cell differentiationabnormal B cell activation +abnormal B cell receptor editingabnormal B cell selection +abnormal class switch recombinationabnormal immature B cell morphology [MP:0005022] (387 genotypes, 552 annotations)abnormal pre-B cell morphology +abnormal transitional stage B cell morphology +absent immature B cells +decreased immature B cell number +increased immature B cell number +abnormal immunoglobulin V(D)J recombination +abnormal memory B cell differentiationabnormal plasma cell differentiationabnormal pro-B cell morphology +abnormal somatic hypermutation frequencyarrested B cell differentiationMouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/08/2013 MGI 5.13 |
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