| MP term: | abnormal regulatory T cell physiology |
| MP id: | MP:0004946 |
| Definition: | any functional anomaly of the specialized subpopulation of T cells that act to suppress activation of the immune system and thus maintain immune system homeostasis and prevent pathological self-reactivity; these may include T cells that express the CD8 transmembrane glycoprotein (CD8-positive T cells), those that express CD4 and CD25 (CD4-positive, CD25-positive regulatory T cells or Tregs) and other T cell types that have suppressor function |
| Number of paths to term: | 3 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
immune system phenotypeabnormal immune system physiologyabnormal adaptive immunityabnormal leukocyte physiologyabnormal lymphocyte physiologyabnormal T cell physiologyabnormal CD4-positive T cell physiology +abnormal CD8-positive T cell physiology +abnormal memory T cell physiology +abnormal NK T cell physiologyabnormal regulatory T cell physiology [MP:0004946] (40 genotypes, 40 annotations)abnormal T cell activation +abnormal T cell apoptosis +immune system phenotypeabnormal immune system physiologyabnormal cell-mediated immunityabnormal leukocyte physiologyabnormal lymphocyte physiologyabnormal T cell physiologyabnormal CD4-positive T cell physiology +abnormal CD8-positive T cell physiology +abnormal memory T cell physiology +abnormal NK T cell physiologyabnormal regulatory T cell physiology [MP:0004946] (40 genotypes, 40 annotations)abnormal T cell activation +abnormal T cell apoptosis +immune system phenotypeabnormal immune system physiologyabnormal immune cell physiologyabnormal leukocyte physiologyabnormal lymphocyte physiologyabnormal T cell physiologyabnormal CD4-positive T cell physiology +abnormal CD8-positive T cell physiology +abnormal memory T cell physiology +abnormal NK T cell physiologyabnormal regulatory T cell physiology [MP:0004946] (40 genotypes, 40 annotations)abnormal T cell activation +abnormal T cell apoptosis +Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
||
|
Citing These Resources Funding Information Warranty Disclaimer & Copyright Notice Send questions and comments to User Support. |
last database update 05/08/2013 MGI 5.13 |
|
|
|
||
Analysis Tools