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Mammalian Phenotype Browser
Term Detail
MP term:abnormal cochlear outer hair cell morphology
Synonym: abnormal auditory outer hair cell morphology
Synonym: abnormal cochlear OHCs
Synonym: abnormal cochlear outer hair cells
MP id: MP:0004399
Definition: any structural anomaly in the sensory cells of the organ of Corti which are in synaptic contact with sensory as well as efferent fibers of the auditory nerve; there are three rows of columnar outer hair cells largely surrounded by cortilymph and supporting phalangeal cells; the apical end of each cell is anchored to the cuticular plate and about 100 stereocilia arranged in a V-shaped pattern extend from the cell's surface through the cuticular plate into the tectorial membrane
Number of paths to term: 6

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-ahearing/vestibular/ear phenotype
                is-aabnormal ear morphology
                        is-aabnormal inner ear morphology
                                is-aabnormal cochlea morphology
                                        is-aabnormal cochlear sensory epithelium morphology
                                                is-aabnormal cochlear hair cell morphology
                                                        is-aabnormal cochlear hair cell development
                                                        is-aabnormal cochlear hair cell number +
                                                        is-aabnormal cochlear hair cell stereociliary bundle morphology +
                                                        is-aabnormal cochlear inner hair cell morphology +
                                                        is-aabnormal cochlear outer hair cell morphology [MP:0004399] (259 genotypes, 396 annotations)
                                                                is-aabnormal cochlear OHC afferent innervation pattern
                                                                is-aabnormal cochlear OHC efferent innervation pattern
                                                                is-aabnormal cochlear outer hair cell number +
                                                                is-aabnormal outer hair cell stereociliary bundle morphology +
                                                                is-acochlear outer hair cell degeneration
                                                                is-ashort cochlear outer hair cells
                                                        is-acochlear hair cell degeneration +


mammalian phenotype
        is-ahearing/vestibular/ear phenotype
                is-aabnormal ear morphology
                        is-aabnormal inner ear morphology
                                is-aabnormal cochlea morphology
                                        is-aabnormal scala media morphology
                                                is-aabnormal organ of Corti morphology
                                                        is-aabnormal cochlear hair cell morphology
                                                                is-aabnormal cochlear hair cell development
                                                                is-aabnormal cochlear hair cell number +
                                                                is-aabnormal cochlear hair cell stereociliary bundle morphology +
                                                                is-aabnormal cochlear inner hair cell morphology +
                                                                is-aabnormal cochlear outer hair cell morphology [MP:0004399] (259 genotypes, 396 annotations)
                                                                        is-aabnormal cochlear OHC afferent innervation pattern
                                                                        is-aabnormal cochlear OHC efferent innervation pattern
                                                                        is-aabnormal cochlear outer hair cell number +
                                                                        is-aabnormal outer hair cell stereociliary bundle morphology +
                                                                        is-acochlear outer hair cell degeneration
                                                                        is-ashort cochlear outer hair cells
                                                                is-acochlear hair cell degeneration +


mammalian phenotype
        is-ahearing/vestibular/ear phenotype
                is-aabnormal ear morphology
                        is-aabnormal inner ear morphology
                                is-aabnormal hair cell morphology
                                        is-aabnormal cochlear hair cell morphology
                                                is-aabnormal cochlear hair cell development
                                                is-aabnormal cochlear hair cell number +
                                                is-aabnormal cochlear hair cell stereociliary bundle morphology +
                                                is-aabnormal cochlear inner hair cell morphology +
                                                is-aabnormal cochlear outer hair cell morphology [MP:0004399] (259 genotypes, 396 annotations)
                                                        is-aabnormal cochlear OHC afferent innervation pattern
                                                        is-aabnormal cochlear OHC efferent innervation pattern
                                                        is-aabnormal cochlear outer hair cell number +
                                                        is-aabnormal outer hair cell stereociliary bundle morphology +
                                                        is-acochlear outer hair cell degeneration
                                                        is-ashort cochlear outer hair cells
                                                is-acochlear hair cell degeneration +


mammalian phenotype
        is-ahearing/vestibular/ear phenotype
                is-aabnormal ear morphology
                        is-aabnormal inner ear morphology
                                is-aabnormal membranous labyrinth morphology
                                        is-aabnormal cochlear labyrinth morphology
                                                is-aabnormal scala media morphology
                                                        is-aabnormal organ of Corti morphology
                                                                is-aabnormal cochlear hair cell morphology
                                                                        is-aabnormal cochlear hair cell development
                                                                        is-aabnormal cochlear hair cell number +
                                                                        is-aabnormal cochlear hair cell stereociliary bundle morphology +
                                                                        is-aabnormal cochlear inner hair cell morphology +
                                                                        is-aabnormal cochlear outer hair cell morphology [MP:0004399] (259 genotypes, 396 annotations)
                                                                                is-aabnormal cochlear OHC afferent innervation pattern
                                                                                is-aabnormal cochlear OHC efferent innervation pattern
                                                                                is-aabnormal cochlear outer hair cell number +
                                                                                is-aabnormal outer hair cell stereociliary bundle morphology +
                                                                                is-acochlear outer hair cell degeneration
                                                                                is-ashort cochlear outer hair cells
                                                                        is-acochlear hair cell degeneration +


mammalian phenotype
        is-anervous system phenotype
                is-aabnormal nervous system morphology
                        is-aabnormal neuron morphology
                                is-aabnormal sensory neuron morphology
                                        is-aabnormal mechanoreceptor morphology
                                                is-aabnormal hair cell morphology
                                                        is-aabnormal cochlear hair cell morphology
                                                                is-aabnormal cochlear hair cell development
                                                                is-aabnormal cochlear hair cell number +
                                                                is-aabnormal cochlear hair cell stereociliary bundle morphology +
                                                                is-aabnormal cochlear inner hair cell morphology +
                                                                is-aabnormal cochlear outer hair cell morphology [MP:0004399] (259 genotypes, 396 annotations)
                                                                        is-aabnormal cochlear OHC afferent innervation pattern
                                                                        is-aabnormal cochlear OHC efferent innervation pattern
                                                                        is-aabnormal cochlear outer hair cell number +
                                                                        is-aabnormal outer hair cell stereociliary bundle morphology +
                                                                        is-acochlear outer hair cell degeneration
                                                                        is-ashort cochlear outer hair cells
                                                                is-acochlear hair cell degeneration +


mammalian phenotype
        is-anervous system phenotype
                is-aabnormal nervous system morphology
                        is-aabnormal somatic nervous system morphology
                                is-aabnormal somatic sensory system morphology
                                        is-aabnormal sensory neuron morphology
                                                is-aabnormal mechanoreceptor morphology
                                                        is-aabnormal hair cell morphology
                                                                is-aabnormal cochlear hair cell morphology
                                                                        is-aabnormal cochlear hair cell development
                                                                        is-aabnormal cochlear hair cell number +
                                                                        is-aabnormal cochlear hair cell stereociliary bundle morphology +
                                                                        is-aabnormal cochlear inner hair cell morphology +
                                                                        is-aabnormal cochlear outer hair cell morphology [MP:0004399] (259 genotypes, 396 annotations)
                                                                                is-aabnormal cochlear OHC afferent innervation pattern
                                                                                is-aabnormal cochlear OHC efferent innervation pattern
                                                                                is-aabnormal cochlear outer hair cell number +
                                                                                is-aabnormal outer hair cell stereociliary bundle morphology +
                                                                                is-acochlear outer hair cell degeneration
                                                                                is-ashort cochlear outer hair cells
                                                                        is-acochlear hair cell degeneration +

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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory