| MP term: | abnormal strial intermediate cell morphology |
| Synonym: | abnormal cochlear melanocytes |
| Synonym: | abnormal otic melanocytes |
| Synonym: | abnormal strial intermediate cells |
| Synonym: | abnormal strial melanocytes |
| Synonym: | abnormal stria vascularis intermediate cells |
| Synonym: | abnormal stria vascularis melanocytes |
| MP id: | MP:0004367 |
| Definition: | any structural anomaly in the melanocytes known to migrate from the neural crest during ontogeny to become located between the epithelial marginal cell layer and the mesodermal basal cell layer within the intrastrial space; the predominant cellular component of the electrogenic machinery that generates an endocochlear potential (80-100 mV) |
| Number of paths to term: | 4 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
hearing/vestibular/ear phenotypeabnormal ear morphologyabnormal inner ear morphologyabnormal cochlea morphologyabnormal scala media morphologyabnormal stria vascularis morphologyabnormal stria vascularis vasculature morphologyabnormal strial basal cell morphology +abnormal strial intermediate cell morphology [MP:0004367] (9 genotypes, 9 annotations)absent strial intermediate cellsabnormal strial marginal cell morphology +stria vascularis degenerationthin stria vascularishearing/vestibular/ear phenotypeabnormal ear morphologyabnormal inner ear morphologyabnormal membranous labyrinth morphologyabnormal cochlear labyrinth morphologyabnormal scala media morphologyabnormal stria vascularis morphologyabnormal stria vascularis vasculature morphologyabnormal strial basal cell morphology +abnormal strial intermediate cell morphology [MP:0004367] (9 genotypes, 9 annotations)absent strial intermediate cellsabnormal strial marginal cell morphology +stria vascularis degenerationthin stria vascularispigmentation phenotypeabnormal extracutaneous pigmentationabnormal otic pigmentationabnormal strial intermediate cell morphology [MP:0004367] (9 genotypes, 9 annotations)absent strial intermediate cellspigmentation phenotypeabnormal melanocyte morphologyabnormal choroid melanocyte morphology +abnormal dermal melanocyte morphologyabnormal epidermal melanocyte morphologyabnormal hair follicle melanocyte morphology +abnormal melanosome morphology +abnormal retinal melanocyte morphology +abnormal strial intermediate cell morphology [MP:0004367] (9 genotypes, 9 annotations)absent strial intermediate cellsectopic melanocytesMouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/22/2013 MGI 5.13 |
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