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Term Detail
MP term:abnormal radial glial cell morphology
Synonym: abnormal radial glia
MP id: MP:0003648
Definition: any structural anomaly of the supporting cells of the developing central nervous system that guide neuronal migration during development and exchange metabolites with developing and migrating neurons; these cells differentiate into astrocytes and some neuronal types in the adult
Number of paths to term: 4

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-acellular phenotype
                is-aabnormal cell physiology
                        is-aabnormal cell differentiation
                                is-aabnormal neuron differentiation
                                        is-aabnormal axon extension +
                                        is-aabnormal axon fasciculation
                                        is-aabnormal axon guidance
                                        is-aabnormal axon pruning
                                        is-aabnormal neuronal precursor cell number +
                                        is-aabnormal Purkinje cell differentiation
                                        is-aabnormal radial glial cell morphology [MP:0003648] (32 genotypes, 32 annotations)
                                        is-aimpaired neuron differentiation
                                        is-apremature neuronal precursor differentiation


mammalian phenotype
        is-anervous system phenotype
                is-aabnormal nervous system morphology
                        is-aabnormal glial cell morphology
                                is-aabnormal CNS glial cell morphology
                                        is-aabnormal astrocyte morphology +
                                        is-aabnormal microglial cell morphology +
                                        is-aabnormal Muller cell morphology
                                        is-aabnormal oligodendrocyte morphology +
                                        is-aabnormal radial glial cell morphology [MP:0003648] (32 genotypes, 32 annotations)
                                        is-aectopic Bergmann glia cells


mammalian phenotype
        is-anervous system phenotype
                is-aabnormal nervous system morphology
                        is-aabnormal nervous system development
                                is-aabnormal neuron differentiation
                                        is-aabnormal axon extension +
                                        is-aabnormal axon fasciculation
                                        is-aabnormal axon guidance
                                        is-aabnormal axon pruning
                                        is-aabnormal neuronal precursor cell number +
                                        is-aabnormal Purkinje cell differentiation
                                        is-aabnormal radial glial cell morphology [MP:0003648] (32 genotypes, 32 annotations)
                                        is-aimpaired neuron differentiation
                                        is-apremature neuronal precursor differentiation


mammalian phenotype
        is-anervous system phenotype
                is-aabnormal nervous system morphology
                        is-aabnormal neuron morphology
                                is-aabnormal neuron differentiation
                                        is-aabnormal axon extension +
                                        is-aabnormal axon fasciculation
                                        is-aabnormal axon guidance
                                        is-aabnormal axon pruning
                                        is-aabnormal neuronal precursor cell number +
                                        is-aabnormal Purkinje cell differentiation
                                        is-aabnormal radial glial cell morphology [MP:0003648] (32 genotypes, 32 annotations)
                                        is-aimpaired neuron differentiation
                                        is-apremature neuronal precursor differentiation

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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory