| MP term: | abnormal radial glial cell morphology |
| Synonym: | abnormal radial glia |
| MP id: | MP:0003648 |
| Definition: | any structural anomaly of the supporting cells of the developing central nervous system that guide neuronal migration during development and exchange metabolites with developing and migrating neurons; these cells differentiate into astrocytes and some neuronal types in the adult |
| Number of paths to term: | 4 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
cellular phenotypeabnormal cell physiologyabnormal cell differentiationabnormal neuron differentiationabnormal axon fasiculationabnormal axon guidanceabnormal axon outgrowth +abnormal axon pruningabnormal neuronal precursor cell number +abnormal Purkinje cell differentiationabnormal radial glial cell morphology [MP:0003648] (31 genotypes, 31 annotations)impaired neuron differentiationpremature neuronal precursor differentiationnervous system phenotypeabnormal nervous system morphologyabnormal glial cell morphologyabnormal CNS glial cell morphologyabnormal astrocyte morphology +abnormal microglial cell morphology +abnormal Muller cell morphologyabnormal oligodendrocyte morphology +abnormal radial glial cell morphology [MP:0003648] (31 genotypes, 31 annotations)ectopic Bergmann glia cellsnervous system phenotypeabnormal nervous system morphologyabnormal nervous system developmentabnormal neuron differentiationabnormal axon fasiculationabnormal axon guidanceabnormal axon outgrowth +abnormal axon pruningabnormal neuronal precursor cell number +abnormal Purkinje cell differentiationabnormal radial glial cell morphology [MP:0003648] (31 genotypes, 31 annotations)impaired neuron differentiationpremature neuronal precursor differentiationnervous system phenotypeabnormal nervous system morphologyabnormal neuron morphologyabnormal neuron differentiationabnormal axon fasiculationabnormal axon guidanceabnormal axon outgrowth +abnormal axon pruningabnormal neuronal precursor cell number +abnormal Purkinje cell differentiationabnormal radial glial cell morphology [MP:0003648] (31 genotypes, 31 annotations)impaired neuron differentiationpremature neuronal precursor differentiationMouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/08/2013 MGI 5.13 |
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