| MP term: | abnormal insulin secretion |
| MP id: | MP:0003564 |
| Definition: | anomaly in the production or release of the hormone secreted by beta cells of the pancreas that promotes glucose utilization, protein synthesis, and the formation and storage of neutral lipids |
| Number of paths to term: | 3 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
endocrine/exocrine gland phenotypeabnormal gland physiologyabnormal pancreas physiologyabnormal endocrine pancreas physiologyabnormal pancreatic beta cell physiologyabnormal insulin secretion [MP:0003564] (217 genotypes, 226 annotations)decreased insulin secretionincreased insulin secretionabnormal pancreatic beta cell proliferation +endocrine/exocrine gland phenotypeabnormal gland physiologyabnormal pancreas physiologyabnormal pancreas secretionabnormal glucagon secretion +abnormal insulin secretion [MP:0003564] (217 genotypes, 226 annotations)decreased insulin secretionincreased insulin secretionabnormal pancreatic ghrelin secretionabnormal pancreatic polypeptide secretionabnormal pancreatic somatostatin secretionhomeostasis/metabolism phenotypeabnormal homeostasisabnormal glucose homeostasisabnormal circulating glucagon level +abnormal circulating glucose level +abnormal circulating insulin level +abnormal glucagon secretion +abnormal gluconeogenesisabnormal glucose tolerance +abnormal glycogen homeostasis +abnormal insulin clearanceabnormal insulin secretion [MP:0003564] (217 genotypes, 226 annotations)decreased insulin secretionincreased insulin secretionabnormal renal glucose reabsorptionabnormal urine glucose level +increased insulin sensitivityinsulin resistanceMouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 06/05/2013 MGI 5.13 |
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