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Mammalian Phenotype Browser
Term Detail
MP term:abnormal insulin secretion
MP id: MP:0003564
Definition: anomaly in the production or release of the hormone secreted by beta cells of the pancreas that promotes glucose utilization, protein synthesis, and the formation and storage of neutral lipids
Number of paths to term: 3

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-aendocrine/exocrine gland phenotype
                is-aabnormal gland physiology
                        is-aabnormal pancreas physiology
                                is-aabnormal endocrine pancreas physiology
                                        is-aabnormal pancreatic beta cell physiology
                                                is-aabnormal insulin secretion [MP:0003564] (248 genotypes, 259 annotations)
                                                        is-adecreased insulin secretion
                                                        is-aincreased insulin secretion
                                                is-aabnormal pancreatic beta cell proliferation +


mammalian phenotype
        is-aendocrine/exocrine gland phenotype
                is-aabnormal gland physiology
                        is-aabnormal pancreas physiology
                                is-aabnormal pancreas secretion
                                        is-aabnormal glucagon secretion +
                                        is-aabnormal insulin secretion [MP:0003564] (248 genotypes, 259 annotations)
                                                is-adecreased insulin secretion
                                                is-aincreased insulin secretion
                                        is-aabnormal pancreatic ghrelin secretion
                                        is-aabnormal pancreatic polypeptide secretion
                                        is-aabnormal pancreatic somatostatin secretion


mammalian phenotype
        is-ahomeostasis/metabolism phenotype
                is-aabnormal homeostasis
                        is-aabnormal glucose homeostasis
                                is-aabnormal circulating glucagon level +
                                is-aabnormal circulating glucose level +
                                is-aabnormal circulating insulin level +
                                is-aabnormal glucagon secretion +
                                is-aabnormal gluconeogenesis
                                is-aabnormal glucose tolerance +
                                is-aabnormal glycogen homeostasis +
                                is-aabnormal hepatic glucose production +
                                is-aabnormal insulin clearance
                                is-aabnormal insulin secretion [MP:0003564] (248 genotypes, 259 annotations)
                                        is-adecreased insulin secretion
                                        is-aincreased insulin secretion
                                is-aabnormal renal glucose reabsorption
                                is-aabnormal urine glucose level +
                                is-aincreased insulin sensitivity
                                is-ainsulin resistance

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last database update
09/16/2014
MGI 5.19
The Jackson Laboratory