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Mammalian Phenotype Browser
Term Detail
MP term:impaired granulosa cell differentiation
MP id: MP:0003357
Definition: atypical production of or inability to produce the supporting cells for the developing female gamete in the ovary of mammals; granulosa cells form a single layer around the mammalian oocyte in the primordial ovarian follicle and advance to form a multilayered cumulus oophorus surrounding the ovum in the Graafian follicle
Number of paths to term: 4

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-acellular phenotype
                is-aabnormal cell physiology
                        is-aabnormal cell differentiation
                                is-aabnormal airway basal cell differentiation
                                is-aabnormal Bergmann glial cell differentiation
                                is-aabnormal dendritic cell differentiation +
                                is-aabnormal enterocyte differentiation
                                is-aabnormal fat cell differentiation +
                                is-aabnormal granulocyte differentiation +
                                is-aabnormal keratinocyte differentiation +
                                is-aabnormal megakaryocyte differentiation
                                is-aabnormal mesenchymal cell differentiation involved in lung development
                                is-aabnormal mononuclear cell differentiation +
                                is-aabnormal myoblast differentiation
                                is-aabnormal myofibroblast differentiation +
                                is-aabnormal neuron differentiation +
                                is-aabnormal organ of Corti supporting cell differentiation +
                                is-aabnormal osteoblast differentiation +
                                is-aabnormal osteoclast differentiation
                                is-aabnormal pancreatic alpha cell differentiation
                                is-aabnormal pancreatic beta cell differentiation
                                is-aabnormal pancreatic delta cell differentiation
                                is-aabnormal pancreatic epsilon cell differentiation
                                is-aabnormal PP cell differentiation
                                is-aabnormal vascular endothelial cell differentiation
                                is-aimpaired granulosa cell differentiation [MP:0003357] (16 genotypes, 16 annotations)
                                        is-aabnormal cumulus oophorus
                                is-aimpaired luteal cell differentiation
                                is-aimpaired neural crest cell differentiation +


mammalian phenotype
        is-aendocrine/exocrine gland phenotype
                is-aabnormal gland morphology
                        is-aabnormal sex gland morphology
                                is-aabnormal ovary morphology
                                        is-aabnormal ovarian follicle morphology
                                                is-aabnormal granulosa cell morphology
                                                        is-aimpaired granulosa cell differentiation [MP:0003357] (16 genotypes, 16 annotations)
                                                                is-aabnormal cumulus oophorus


mammalian phenotype
        is-areproductive system phenotype
                is-aabnormal reproductive system morphology
                        is-aabnormal female reproductive system morphology
                                is-aabnormal female genitalia morphology
                                        is-aabnormal internal female genitalia morphology
                                                is-aabnormal ovary morphology
                                                        is-aabnormal ovarian follicle morphology
                                                                is-aabnormal granulosa cell morphology
                                                                        is-aimpaired granulosa cell differentiation [MP:0003357] (16 genotypes, 16 annotations)
                                                                                is-aabnormal cumulus oophorus


mammalian phenotype
        is-areproductive system phenotype
                is-aabnormal reproductive system morphology
                        is-aabnormal sex gland morphology
                                is-aabnormal ovary morphology
                                        is-aabnormal ovarian follicle morphology
                                                is-aabnormal granulosa cell morphology
                                                        is-aimpaired granulosa cell differentiation [MP:0003357] (16 genotypes, 16 annotations)
                                                                is-aabnormal cumulus oophorus

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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory